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INSIG2 gene polymorphism is associated with increased subcutaneous fat in women and poor response to resistance training in men
| Title: | INSIG2 gene polymorphism is associated with increased subcutaneous fat in women and poor response to resistance training in men. |
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| Name(s): |
Orkunoglu-Suer, Funda E., creator Gordish-Dressman, Heather, creator Clarkson, Priscilla M., creator Thompson, Paul D., creator Angelopoulos, Theodore J., creator Gordon, Paul M., creator Moyna, Niall M., creator Pescatello, Linda S., creator Visich, Paul S., creator Zoeller, Robert F., creator Harmon, Brennan, creator Seip, Richard L., creator Hoffman, Eric P., creator Devaney, Joseph M., creator |
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| Type of Resource: | text | |
| Date Issued: | 2008-12-23 | |
| Physical Description: | text/pdf[9p.] | |
| Language(s): | English | |
| Identifier: | 3327172 (digitool), FADT3327172 (IID), fau:1944 (fedora), 10.1186/1471‐2350‐9‐117 (doi) | |
| Note(s): | Background: A common SNP upstream of the INSIG2 gene, rs7566605 (g.-10,1025G>C,Chr2:118,552,255, NT_022135.15), was reported to be associated with obesity (Body Mass Index,[BMI]) in a genome-wide association scan using the Framingham Heart Study but has not been reproduced in other cohorts. As BMI is a relatively insensitive measure of adiposity that is subject to many confounding variables, we sought to determine the relationship between the INSIG2 SNPand subcutaneous fat volumes measured by MRI in a young adult population. | |
| Subject(s): |
Adiposity --genetics Alleles Gene Frequency Intracellular Signaling Peptides and Proteins Resistance Training Subcutaneous Fat INSIG2 protein Obesity Genotype Membrane Proteins Membrane Proteins --Genetics |
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| Persistent Link to This Record: | http://purl.flvc.org/fcla/dt/3327172 | |
| Host Institution: | FAU |
