You are here

biosynthetic production of pseudopterosin C: An anti-inflammatory agent from a marine soft coral

Download pdf | Full Screen View

Date Issued:
1998
Summary:
Pseudopterosin C is a novel diterpene glycoside isolated from the Caribbean gorgonian coral, Pseudopterogorgia elisabethae. Pseudopterosin C is non-steroidal and has been shown to exhibit promising anti-inflammatory and analgesic properties. The in vitro production of pseudopterosin C through biosynthetic methods has been examined. A cell-free system as well as an enzyme precipitate capable of transforming terpene precursors to the product has been developed. The parameters toward optimizing the enzymatic production through cofactor requirements, differing terpene precursors and sugars were investigated.
Title: The biosynthetic production of pseudopterosin C: An anti-inflammatory agent from a marine soft coral.
113 views
34 downloads
Name(s): Mydlarz, Laura D.
Florida Atlantic University, Degree Grantor
Kerr, Russell G., Thesis Advisor
Binninger, David, Thesis Advisor
Type of Resource: text
Genre: Electronic Thesis Or Dissertation
Issuance: monographic
Date Issued: 1998
Publisher: Florida Atlantic University
Place of Publication: Boca Raton, Fla.
Physical Form: application/pdf
Extent: 75 p.
Language(s): English
Summary: Pseudopterosin C is a novel diterpene glycoside isolated from the Caribbean gorgonian coral, Pseudopterogorgia elisabethae. Pseudopterosin C is non-steroidal and has been shown to exhibit promising anti-inflammatory and analgesic properties. The in vitro production of pseudopterosin C through biosynthetic methods has been examined. A cell-free system as well as an enzyme precipitate capable of transforming terpene precursors to the product has been developed. The parameters toward optimizing the enzymatic production through cofactor requirements, differing terpene precursors and sugars were investigated.
Identifier: 9780599009189 (isbn), 15588 (digitool), FADT15588 (IID), fau:12348 (fedora)
Note(s): Thesis (M.S.)--Florida Atlantic University, 1998.
Subject(s): Anti-inflammatory agents
Alcyonacea
Synthetic drugs
Held by: Florida Atlantic University Libraries
Persistent Link to This Record: http://purl.flvc.org/fcla/dt/15588
Sublocation: Digital Library
Use and Reproduction: Copyright © is held by the author with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
Use and Reproduction: http://rightsstatements.org/vocab/InC/1.0/
Host Institution: FAU
Is Part of Series: Florida Atlantic University Digital Library Collections.