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The effect of choline supplementation on maze running ability in hypothyroid rats

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Date Issued:
1998
Summary:
The effects of perinatal hypothyroidism and perinatal choline supplementation on radial arm maze performance were assessed. Animals were made hypothyroid by the administration of propylthiouracil (PTU) to the mash of dams from prenatal day 15 until postnatal day 15. Choline chloride was administered prenatally in drinking water and postnatally through injections to the pups until day 24. Hypothyroid animals made significantly more reference and working memory errors than did euthyroid animals. Perinatal choline supplementation reduced the number of working memory errors, but not reference memory errors, in both euthyroid and hypothyroid animals.
Title: The effect of choline supplementation on maze running ability in hypothyroid rats.
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Name(s): Ramer, Jessica
Florida Atlantic University, Degree Grantor
Charles E. Schmidt College of Science
Department of Psychology
Type of Resource: text
Genre: Electronic Thesis Or Dissertation
Issuance: monographic
Date Issued: 1998
Publisher: Florida Atlantic University
Place of Publication: Boca Raton, Fla.
Physical Form: application/pdf
Extent: 62 p.
Language(s): English
Summary: The effects of perinatal hypothyroidism and perinatal choline supplementation on radial arm maze performance were assessed. Animals were made hypothyroid by the administration of propylthiouracil (PTU) to the mash of dams from prenatal day 15 until postnatal day 15. Choline chloride was administered prenatally in drinking water and postnatally through injections to the pups until day 24. Hypothyroid animals made significantly more reference and working memory errors than did euthyroid animals. Perinatal choline supplementation reduced the number of working memory errors, but not reference memory errors, in both euthyroid and hypothyroid animals.
Identifier: 9780591929997 (isbn), 15582 (digitool), FADT15582 (IID), fau:12342 (fedora)
Note(s): Thesis (M.A.)--Florida Atlantic University, 1998.
Charles E. Schmidt College of Science
Subject(s): Rats as laboratory animals
Hypothyroidism
Held by: Florida Atlantic University Libraries
Persistent Link to This Record: http://purl.flvc.org/fcla/dt/15582
Sublocation: Digital Library
Use and Reproduction: Copyright © is held by the author with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
Use and Reproduction: http://rightsstatements.org/vocab/InC/1.0/
Host Institution: FAU
Is Part of Series: Florida Atlantic University Digital Library Collections.