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Employment of modern analytical methods for adsorption studies and pharmaceutical analysis

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Date Issued:
1997
Summary:
Ultraviolet spectrophotometry was employed to investigate the adsorption of phenylphosphonic acid onto the surface of alumina from aqueous solution. It was found that an initial chemisorption occurred with monolayer coverage, reaching a maximum at a solution pH of 3.0. The results were interpreted as indicating that this and related adsorptions are controlled by ligand exchange processes involving electrostatic attraction between oppositely-charged species. In a separate project, high performance liquid chromatography was employed for the quantitative analysis of aminophylline in commercial thigh cream formulations. The analysis required derivatization of the compound by dansylation under carefully-controlled conditions. This enhanced its detection and separation from other cream components.
Title: Employment of modern analytical methods for adsorption studies and pharmaceutical analysis.
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Name(s): Foss, Wendy Marie
Florida Atlantic University, Degree Grantor
Haky, Jerome E., Thesis Advisor
Type of Resource: text
Genre: Electronic Thesis Or Dissertation
Issuance: monographic
Date Issued: 1997
Publisher: Florida Atlantic University
Place of Publication: Boca Raton, Fla.
Physical Form: application/pdf
Extent: 77 p.
Language(s): English
Summary: Ultraviolet spectrophotometry was employed to investigate the adsorption of phenylphosphonic acid onto the surface of alumina from aqueous solution. It was found that an initial chemisorption occurred with monolayer coverage, reaching a maximum at a solution pH of 3.0. The results were interpreted as indicating that this and related adsorptions are controlled by ligand exchange processes involving electrostatic attraction between oppositely-charged species. In a separate project, high performance liquid chromatography was employed for the quantitative analysis of aminophylline in commercial thigh cream formulations. The analysis required derivatization of the compound by dansylation under carefully-controlled conditions. This enhanced its detection and separation from other cream components.
Identifier: 9780591333978 (isbn), 15404 (digitool), FADT15404 (IID), fau:12171 (fedora)
Note(s): Thesis (M.S.)--Florida Atlantic University, 1997.
Subject(s): Adsorption
Spectrophotometry
Chromatographic analysis
Solution (Chemistry)
Held by: Florida Atlantic University Libraries
Persistent Link to This Record: http://purl.flvc.org/fcla/dt/15404
Sublocation: Digital Library
Use and Reproduction: Copyright © is held by the author with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
Use and Reproduction: http://rightsstatements.org/vocab/InC/1.0/
Host Institution: FAU
Is Part of Series: Florida Atlantic University Digital Library Collections.