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Effects of power line (60 Hz) electromagnetic fields on protein phosphorylation in the yeast Saccharomyces cerevisiae

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Date Issued:
1995
Summary:
Epidemiological studies have suggested that 60 Hz AC electromagnetic fields (EMF) generated by power lines might play a role in the increased incidence of certain human cancers, especially in children. Previous studies with human cells indicate that one molecular mechanism may involve differential effects on protein phosphorylation. The aim of this thesis was to determine whether 60 HZ EMF also affect phosphorylation in the yeast Saccharomyces cerevisiae which has been developed into a paradigm for molecular biologists. The data presented in this thesis show that protein phosphorylation is indeed altered in yeast in response to 60 Hz EMF. This work validates yeast as an experimental model for more in depth investigation of the molecular and genetic basis of this response. Insight gained from these studies should shed light on the interaction of power line EMF with human cells and its possible role in development of human cancers.
Title: Effects of power line (60 Hz) electromagnetic fields on protein phosphorylation in the yeast Saccharomyces cerevisiae.
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Name(s): Ross, Mary Alice
Florida Atlantic University, Degree grantor
Binninger, David, Thesis advisor
Type of Resource: text
Genre: Electronic Thesis Or Dissertation
Issuance: monographic
Date Issued: 1995
Publisher: Florida Atlantic University
Place of Publication: Boca Raton, Fla.
Physical Form: application/pdf
Extent: 66 p.
Language(s): English
Summary: Epidemiological studies have suggested that 60 Hz AC electromagnetic fields (EMF) generated by power lines might play a role in the increased incidence of certain human cancers, especially in children. Previous studies with human cells indicate that one molecular mechanism may involve differential effects on protein phosphorylation. The aim of this thesis was to determine whether 60 HZ EMF also affect phosphorylation in the yeast Saccharomyces cerevisiae which has been developed into a paradigm for molecular biologists. The data presented in this thesis show that protein phosphorylation is indeed altered in yeast in response to 60 Hz EMF. This work validates yeast as an experimental model for more in depth investigation of the molecular and genetic basis of this response. Insight gained from these studies should shed light on the interaction of power line EMF with human cells and its possible role in development of human cancers.
Identifier: 15145 (digitool), FADT15145 (IID), fau:11918 (fedora)
Collection: FAU Electronic Theses and Dissertations Collection
Note(s): Thesis (M.S.)--Florida Atlantic University, 1995.
Charles E. Schmidt College of Science
Subject(s): Electric lines--Health aspects
Electromagnetic fields--Health aspects
Saccharomyces cerevisiae
Held by: Florida Atlantic University Libraries
Persistent Link to This Record: http://purl.flvc.org/fcla/dt/15145
Sublocation: Digital Library
Use and Reproduction: Copyright © is held by the author with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
Use and Reproduction: http://rightsstatements.org/vocab/InC/1.0/
Host Institution: FAU
Is Part of Series: Florida Atlantic University Digital Library Collections.