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TRIIODOTHYRONEMIA - DISTINGUISHING THE HYPOTHYROID PATIENT FROM NON-THYROIDAL ILLNESS

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Date Issued:
1982
Summary:
Non-thyroidal illness (NTI) is frequently characterized by triiodothyronemia (low T3) and abnormal thyroid function tests. This could result in an incorrect diagnosis of hypothyroidism. The purpose of this study was to determine which thyroid function test or group of tests could be used to identify those euthyroid patients with NTI. A total of seventy patients with triiodothyronemia were clinically evaluated and tested for: total T4 , normalized T4, "free'' T4, total T3, reverse T3 , T3 uptake, free thyroxine index, and TSH. Commercially available radioassay kits were used in testing. The patients were separated into four groups: primary hypothyroid, secondary hypothyroid, hypothyroid with NTI, and euthyroid with NTI. The results correctly identified the primary and secondary hypothyroid patients and those hypothyroid patients with NTI. The normalized T4 test accurately identified those euthyroid patients with NTI and triiodothyronemia 94 percent of the time.
Title: TRIIODOTHYRONEMIA - DISTINGUISHING THE HYPOTHYROID PATIENT FROM NON-THYROIDAL ILLNESS.
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Name(s): Butler, Cynthia W.
Florida Atlantic University, Degree grantor
Clark, Samuel F., Thesis advisor
Type of Resource: text
Genre: Electronic Thesis Or Dissertation
Issuance: monographic
Date Issued: 1982
Publisher: Florida Atlantic University
Place of Publication: Boca Raton, Fla.
Physical Form: pdf
Extent: 47 p.
Language(s): English
Summary: Non-thyroidal illness (NTI) is frequently characterized by triiodothyronemia (low T3) and abnormal thyroid function tests. This could result in an incorrect diagnosis of hypothyroidism. The purpose of this study was to determine which thyroid function test or group of tests could be used to identify those euthyroid patients with NTI. A total of seventy patients with triiodothyronemia were clinically evaluated and tested for: total T4 , normalized T4, "free'' T4, total T3, reverse T3 , T3 uptake, free thyroxine index, and TSH. Commercially available radioassay kits were used in testing. The patients were separated into four groups: primary hypothyroid, secondary hypothyroid, hypothyroid with NTI, and euthyroid with NTI. The results correctly identified the primary and secondary hypothyroid patients and those hypothyroid patients with NTI. The normalized T4 test accurately identified those euthyroid patients with NTI and triiodothyronemia 94 percent of the time.
Identifier: 14105 (digitool), FADT14105 (IID), fau:10919 (fedora)
Collection: FAU Electronic Theses and Dissertations Collection
Note(s): Thesis (M.S.T.)--Florida Atlantic University, 1982.
Charles E. Schmidt College of Science
Subject(s): Thyroid gland--Diseases--Diagnosis
Thyroid gland function tests
Held by: Florida Atlantic University Libraries
Persistent Link to This Record: http://purl.flvc.org/fcla/dt/14105
Sublocation: Digital Library
Use and Reproduction: Copyright © is held by the author, with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
Use and Reproduction: http://rightsstatements.org/vocab/InC/1.0/
Host Institution: FAU
Is Part of Series: Florida Atlantic University Digital Library Collections.