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New conopeptides from Conus jaspedius

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Date Issued:
2004
Summary:
Cone snails (genus conus) are marine gastropods of tropical waters. They capture their prey by envenomation and for this; they have evolved a highly efficient and diverse venom cocktail of proteins and peptides. This has elicited extreme interest in venom composition and their molecular targets. In this study, the venom of Conus jaspedius, a small Atlantic cone snail was extracted, venom components isolated and analyzed, by a combination of Size exclusion and High performance liquid chromatography, NMR, Mass spectrometry and Edman sequencing. Here, four novel conopeptide sequences are reported, namely; an alpha conotoxin, a member of the A and O superfamilies and a new family.
Title: New conopeptides from Conus jaspedius.
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Name(s): Williams, Orette St. Aubyn
Florida Atlantic University, Degree Grantor
Mari, Frank, Thesis Advisor
Type of Resource: text
Genre: Electronic Thesis Or Dissertation
Issuance: monographic
Date Issued: 2004
Publisher: Florida Atlantic University
Place of Publication: Boca Raton, Fla.
Physical Form: application/pdf
Extent: 62 p.
Language(s): English
Summary: Cone snails (genus conus) are marine gastropods of tropical waters. They capture their prey by envenomation and for this; they have evolved a highly efficient and diverse venom cocktail of proteins and peptides. This has elicited extreme interest in venom composition and their molecular targets. In this study, the venom of Conus jaspedius, a small Atlantic cone snail was extracted, venom components isolated and analyzed, by a combination of Size exclusion and High performance liquid chromatography, NMR, Mass spectrometry and Edman sequencing. Here, four novel conopeptide sequences are reported, namely; an alpha conotoxin, a member of the A and O superfamilies and a new family.
Identifier: 9780542444852 (isbn), 13303 (digitool), FADT13303 (IID), fau:10155 (fedora)
Note(s): Thesis (M.S.)--Florida Atlantic University, 2004.
Subject(s): Venom
Gastropoda--Venom
Poisonous animals
Peptides--Structure
Held by: Florida Atlantic University Libraries
Persistent Link to This Record: http://purl.flvc.org/fcla/dt/13303
Sublocation: Digital Library
Use and Reproduction: Copyright © is held by the author with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
Use and Reproduction: http://rightsstatements.org/vocab/InC/1.0/
Host Institution: FAU
Is Part of Series: Florida Atlantic University Digital Library Collections.