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Diterpene biosynthesis in early ontogenetic stages of Pseudopterogorgia elisabethae and Pseudopterogorgia bipinnata
- Date Issued:
- 2005
- Summary:
- There is growing evidence that secondary metabolites isolated from some marine invertebrates may actually be produced by a symbiont. The capacity of early ontogenetic stages of Pseudopterogorgia elisabethae and Pseudopterogorgia bipinnata to biosynthesize biologically active and pharmaceutically important diterpenes was examined. These early life stages lack the algal symbionts found in adult colonies of the species, thus removing one level of complexity. The larvae and polyps of these two species produced high concentrations of the diterpenoid secondary metabolites, one of which proved to significantly deter fish-feeding in in situ feeding assays. Additionally, a novel cembrenoid diterpene was isolated from P. bipinnata. The structure of this compound, bipinnatolide L (40) was solved using 1D and 2D NMR experiments.
Title: | Diterpene biosynthesis in early ontogenetic stages of Pseudopterogorgia elisabethae and Pseudopterogorgia bipinnata. |
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Name(s): |
Mukherjee, Maia Stapleton Florida Atlantic University, Degree Grantor Charles E. Schmidt College of Science Department of Chemistry and Biochemistry |
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Type of Resource: | text | |
Genre: | Electronic Thesis Or Dissertation | |
Issuance: | monographic | |
Date Issued: | 2005 | |
Publisher: | Florida Atlantic University | |
Place of Publication: | Boca Raton, Fla. | |
Physical Form: | application/pdf | |
Extent: | 97 p. | |
Language(s): | English | |
Summary: | There is growing evidence that secondary metabolites isolated from some marine invertebrates may actually be produced by a symbiont. The capacity of early ontogenetic stages of Pseudopterogorgia elisabethae and Pseudopterogorgia bipinnata to biosynthesize biologically active and pharmaceutically important diterpenes was examined. These early life stages lack the algal symbionts found in adult colonies of the species, thus removing one level of complexity. The larvae and polyps of these two species produced high concentrations of the diterpenoid secondary metabolites, one of which proved to significantly deter fish-feeding in in situ feeding assays. Additionally, a novel cembrenoid diterpene was isolated from P. bipinnata. The structure of this compound, bipinnatolide L (40) was solved using 1D and 2D NMR experiments. | |
Identifier: | 9780542407031 (isbn), 13297 (digitool), FADT13297 (IID), fau:10149 (fedora) | |
Collection: | FAU Electronic Thesis or Dissertation Collection | |
Note(s): |
Adviser: Russell Kerr. Thesis (M.S.)--Florida Atlantic University, 2005. |
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Subject(s): | Chemistry, Biochemistry | |
Held by: | Florida Atlantic University Libraries | |
Persistent Link to This Record: | http://purl.flvc.org/fcla/dt/13297 | |
Sublocation: | Digital Library | |
Use and Reproduction: | Copyright © is held by Maia Stapleton Mukherjee, the author, with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder. | |
Use and Reproduction: | http://rightsstatements.org/vocab/InC/1.0/ | |
Host Institution: | FAU | |
Is Part of Series: | FAU Digital Library Collections. |