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Title: Biomass offsets little or none of permafrost carbon release from soils, streams, and wildfire: an expert assessment.
Creator: Abbott, Benjamin W., Jones, Jeremy B., Schuur, Edward A. G., Chapin III, F. Stuart, Bowden, William B., Bret-Harte, M. Syndonia, Epstein, Howard E., Flannigan, Michael D., Harms, Tamara K., Hollingsworth, Teresa N., Mack, Michelle C., McGuire, A. David, Natali, Susan M., Rocha, Adrian V., Tank, Suzanne E., Turetsky, Merritt R., Vonk, Jorien E., Wickland, Kimberly P., Aiken, George R., Alexander, Heather D., Amon, Rainer M. W., Benscoter, Brian, Bergeron, Yves, Bishop, Kevin, Blarquez, Olivier, Bond-Lamberty, Ben, Breen, Amy L., Buffam, Ishi, Cai, Yihua, Carcaillet, Christopher, Carey, Sean K., Chen, Jing M., Chen, Han Y. H., Christensen, Torben R., Cooper, Lee W., Cornelissen, J. Hans C., de Groot, William J., DeLuca, Thomas H., Dorrepaal, Ellen, Fetcher, Ned, Finlay, Jacques C., Forbes, Bruce C., French, Nancy H. F., Gauthier, Sylvie, Girardin, Martin P., Goetz, Scott J., Goldammer, Johann G., Gough, Laura, Grogan, Paul, Guo, Laodong, Higuera, Philip E., Hinzman, Larry, Hu, Feng Sheng, Hugelius, Gustaf, Jafarov, Elchin E., Jandt, Randi, Johnstone, Jill F., Jan Karlsson, Kasischke, Eric S., Kattner, Gerhard, Kelly, Ryan, Keuper, Frida, Kling, George W., Kortelainen, Pirkko, Kouki, Jari, Kuhry, Peter, Laudon, Hjalmar, Laurion, Isabelle, Macdonald, Robie W., Mann, Paul J., Martikainen, Pertti J., McClelland, James W., Molau, Ulf, Oberbauer, Steven F., Olefeldt, David, Paré, David, Parisien, Marc-André, Payette, Serge, Peng, Changhui, Pokrovsky, Oleg S., Rastetter, Edward B., Raymond, Peter A., Raynolds, Martha K., Rein, Guillermo, Reynolds, James F., Robards, Martin, Rogers, Brendan M., Schädel, Christina, Schaefer, Kevin, Schmidt, Inger K., Shvidenko, Anatoly, Sky, Jasper, Spencer, Robert G. M., Starr, Gregory, Striegl, Robert G., Teisserenc, Roman, Tranvik, Lars J., Virtanen, Tarmo, Welker, Jeffrey M., Zimov, Sergei
Date Issued: 2016-03-07
PURL: http://purl.flvc.org/fau/fd/FAUIR000121
Format: Citation

Title: An Exploration of Indexed and Non-Indexed Open Access Journals: Identifying Metadata Coding Variations.
Creator: Allen, Ethan J., Weber, Roberta K.
Date Issued: 2015-07-03
PURL: http://purl.flvc.org/fau/fd/FAUIR000116
Format: Citation

Title: Preparing Pre-service Teachers to Implement Genocide Studies in Florida’s Elementary Schools: A mixed methods study to ascertain effectiveness of a Genocide Studies Unit.
Creator: Allgood, Ilene, Shah, Rachayita
Date Issued: 2016
PURL: http://purl.flvc.org/fau/fd/FAUIR000238
Format: Citation

Title: The brain decade in debate: VII. Neurobiology of sleep and dreams.
Creator: Aloe, F., Amzica, F., Hening, W., Menna-Barreto, L., Pinto Jr., L.R., Velluti, R., Vertes, Robert P., Timo-Iaria, C.
Date Issued: 2001-12
PURL: http://purl.flvc.org/fau/fd/FAUIR000196
Format: Citation

Title: Language and Visual Perception Associations: Meta-Analytic Connectivity Modeling of Brodmann Area 37.
Creator: Ardila, Alfredo, Bernal, Byron, Rosselli, Monica
Date Issued: 2015
PURL: http://purl.flvc.org/fau/fd/FAUIR000181
Format: Citation

Title: Glial Hsp70 Protects K+ Homeostasis in the Drosophila Brain during Repetitive Anoxic Depolarization.
Creator: Armstrong, Gary A. B., Xiao, Chengfeng, Krill, Jennifer L., Seroude, Laurent, Dawson-Scully, Ken, Robertson, R. Meldrum, Roman, Gregg
Abstract/Description: Neural tissue is particularly vulnerable to metabolic stress and loss of ion homeostasis. Repetitive stress generally leads to more permanent dysfunction but the mechanisms underlying this progression are poorly understood. We investigated the effects of energetic compromise in Drosophila by targeting the Na+/K+-ATPase. Acute ouabain treatment of intact flies resulted in subsequent repetitive comas that led to death and were associated with transient loss of K+ homeostasis in the brain. Heat...
Show moreNeural tissue is particularly vulnerable to metabolic stress and loss of ion homeostasis. Repetitive stress generally leads to more permanent dysfunction but the mechanisms underlying this progression are poorly understood. We investigated the effects of energetic compromise in Drosophila by targeting the Na+/K+-ATPase. Acute ouabain treatment of intact flies resulted in subsequent repetitive comas that led to death and were associated with transient loss of K+ homeostasis in the brain. Heat shock pre-conditioned flies were resistant to ouabain treatment. To control the timing of repeated loss of ion homeostasis we subjected flies to repetitive anoxia while recording extracellular [K+] in the brain. We show that targeted expression of the chaperone protein Hsp70 in glial cells delays a permanent loss of ion homeostasis associated with repetitive anoxic stress and suggest that this is a useful model for investigating molecular mechanisms of neuroprotection.
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Date Issued: 2011-12-12
PURL: http://purl.flvc.org/fau/fd/FAUIR000078
Format: Citation

Title: Dorsal anterior cingulate cortex modulates supplementary motor area in coordinated unimanual motor behavior.
Creator: Asemi, Avisa, Ramaseshan, Karthik, Burgess, Ashley, Diwadkar, Vaibhav A., Bressler, Steven L.
Date Issued: 2015-06-04
PURL: http://purl.flvc.org/fau/fd/FAUIR000126
Format: Citation

Title: Engineering cancer microenvironments for in vitro 3-D tumor models.
Creator: Asghar, Waseem, El Assal, Rami, Shafiee, Hadi, Pitteri, Sharon, Paulmurugan, Ramasamy, Demirci, Utkan
Abstract/Description: The natural microenvironment of tumors is composed of extracellular matrix (ECM), blood vasculature, and supporting stromal cells. The physical characteristics of ECM as well as the cellular components play a vital role in controlling cancer cell proliferation, apoptosis, metabolism, and differentiation. To mimic the tumor microenvironment outside the human body for drug testing, two-dimensional (2-D) and murine tumor models are routinely used. Although these conventional approaches are...
Show moreThe natural microenvironment of tumors is composed of extracellular matrix (ECM), blood vasculature, and supporting stromal cells. The physical characteristics of ECM as well as the cellular components play a vital role in controlling cancer cell proliferation, apoptosis, metabolism, and differentiation. To mimic the tumor microenvironment outside the human body for drug testing, two-dimensional (2-D) and murine tumor models are routinely used. Although these conventional approaches are employed in preclinical studies, they still present challenges. For example, murine tumor models are expensive and difficult to adopt for routine drug screening. On the other hand, 2-D in vitro models are simple to perform, but they do not recapitulate natural tumor microenvironment, because they do not capture important three-dimensional (3-D) cell–cell, cell–matrix signaling pathways, and multi-cellular heterogeneous components of the tumor microenvironment such as stromal and immune cells. The three-dimensional (3-D) in vitro tumor models aim to closely mimic cancer microenvironments and have emerged as an alternative to routinely used methods for drug screening. Herein, we review recent advances in 3-D tumor model generation and highlight directions for future applications in drug testing.
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Date Issued: 2015-12
PURL: http://purl.flvc.org/fau/fd/FAUIR000000
Format: Citation

Title: Engineering long shelf life multi-layer biologically active surfaces on microfluidic devices for point of care applications.
Creator: Asghar, Waseem, Yuksekkaya, Mehmet, Shafiee, Hadi, Zhang, Michael, Ozen, Mehmet O., Inci, Fatih, Kocakulak, Mustafa, Demirci, Utkan
Date Issued: 2016-08-17
PURL: http://purl.flvc.org/fau/fd/FAUIR000118
Format: Citation

Title: Glucocorticoid Receptor (NR3C1) Variants Associate with the Muscle Strength and Size Response to Resistance Training.
Creator: Ash, Garrett I., Kostek, Matthew A., Lee, Harold, Angelopoulos, Theodore J., Clarkson, Priscilla M., Gordon, Paul M., Moyna, Niall M., Visich, Paul S., Zoeller, Robert F., Price, Thomas B., Devaney, Joseph M., Gordish-Dressman, Heather, Thompson, Paul D., Hoffman, Eric P., Pescatello, Linda S., Fine, Michael L
Abstract/Description: Glucocorticoid receptor (NR3C1) polymorphisms associate with obesity, muscle strength, and cortisol sensitivity. We examined associations among four NR3C1 polymorphisms and the muscle response to resistance training (RT). European-American adults (n = 602, 23.8±0.4yr) completed a 12 week unilateral arm RT program. Maximum voluntary contraction (MVC) assessed isometric strength (kg) and MRI assessed biceps size (cm^2) preand post-resistance training. Subjects were genotyped for NR3C1 -2722G>A,...
Show moreGlucocorticoid receptor (NR3C1) polymorphisms associate with obesity, muscle strength, and cortisol sensitivity. We examined associations among four NR3C1 polymorphisms and the muscle response to resistance training (RT). European-American adults (n = 602, 23.8±0.4yr) completed a 12 week unilateral arm RT program. Maximum voluntary contraction (MVC) assessed isometric strength (kg) and MRI assessed biceps size (cm^2) preand post-resistance training. Subjects were genotyped for NR3C1 -2722G>A, -1887G>A, -1017T>C, and +363A>G. Men carrying the -2722G allele gained less relative MVC (17.3 ±1.2vs33.5±6.1%) (p = 0.010) than AA homozygotes; men with -1887GG gained greater relative MVC than A allele carriers (19.6±1.4vs13.2±2.3%) (p = 0.016). Women carrying the -1017T allele gained greater relative size (18.7±0.5vs16.1±0.9%) (p = 0.016) than CC homozygotes.We found sex-specific NR3C1 associations with the muscle strength and size response to RT. Future studies should investigate whether these associations are partially explained by cortisol’s actions in muscle tissue as they interact with sex differences in cortisol production.
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Date Issued: 2016-01-28
PURL: http://purl.flvc.org/fau/fd/FAUIR000062
Format: Citation

Title: Tissue inhibitor of metalloproteinases-1 protects human neurons from staurosporine and HIV-1-induced apoptosis: mechanisms and relevance to HIV-1-associated dementia.
Creator: Ashutosh, Chao, C, Borgmann, K, Brew, Keith, Ghorpade, A
Date Issued: 2012-06
PURL: http://purl.flvc.org/fau/fd/FAUIR000129
Format: Citation

Title: Combination of Sulindac and Dichloroacetate Kills Cancer Cells via Oxidative Damage.
Creator: Ayyanathan, Kasirajan, Kesaraju, Shailaja, Dawson-Scully, Ken, Weissbach, Herbert, Bauer, Joseph Alan
Date Issued: 2012-07-17
PURL: http://purl.flvc.org/fau/fd/FAUIR000091
Format: Citation

Title: Stem cell harvesting protocol research in autologous transplantation setting: Large volume vs. conventional cytapheresis.
Creator: Balint, Bela, Ljubenov, Marika, Stamatovic, Dragana, Todorovic, Milena, Pavlovic, Mirjana, Ostojic, Gordana, Jocic, Miodrag, Trkuljic, Miroljub
Abstract/Description: Background/Aim. The use of peripheral blood as a source of hematopoietic stem cells (SCs) is progressively increasing and has nearly supplanted bone marrow transplantation. Interpatient variability in the degree and kinetics of SC mobilization into peripheral blood is an expected event after conventional chemotherapy–based treatment, followed by sequential administration of recombinant granulocyte–colony– stimulating factor (rHu–CSF). In this study, specific factors associated with the...
Show moreBackground/Aim. The use of peripheral blood as a source of hematopoietic stem cells (SCs) is progressively increasing and has nearly supplanted bone marrow transplantation. Interpatient variability in the degree and kinetics of SC mobilization into peripheral blood is an expected event after conventional chemotherapy–based treatment, followed by sequential administration of recombinant granulocyte–colony– stimulating factor (rHu–CSF). In this study, specific factors associated with the application of two different SC–harvesting approaches, including the use of large volume leukapheresis (LVL) vs. repetitive conventional apheresis (RCA), were analyzed. The basic goal of the study was to evaluate the influence of apheresis protocol (collection timing, processed blood volume and cell yield) upon the clinical outcome of transplantation. Methods. Results obtained by LVL (76 pts) and RCA (20 pts – control group) were compared. The SC mobilizing regimen used was cyclophosphamide (4–7 g/m^2) or polychemotherapy and rHuG–CSF 10–16 μg/kg of body mess (bm) per day. Cell harvesting was performed using COBE-Spectra (Caridian–BCT, USA). The volume of processed blood in LVL setting was ≥ 3.5 – fold of the patient's circulating blood quantity (ranged from 12.7 to 37.8 l). All patients tolerated well the use of intensive treatment, without any side or adverse effects. Our original controlled–rate cryopreservation was carried out with 10% dimethyl sulfoxide (DMSO) using Planer R203/200R or Planer 560–16 equipments (Planer Products Ltd, UK). Total nucleated cell (NC) and mononuclear cell (MNC) counts were examined by flow cytometry (Advia–2120 Bayer, Germany; Technicon H–3 System, USA). The CD34+ cell surface antigen was investigated by the EPICS XL–MCL device (Coulter, Germany). Results. Performing LVL–apheresis, high–level MNC and CD34+ cell yields (7.6±4.6 × 10^8/kg bm and 11.8±6.5 × 10^6/kg bm, respectively) were obtained. As a result, rapid hematopoietic reconstitution ("graft–healing") – on the 9.4th and 12.4th day for granulocytes and platelets, respectively was achieved. Using repetitive conventional apheresis (2–3 procedures), the total MNC count was high (8.2±7.0 × 10^8/kg bm), but the total CD34+ yield was lower 10.8±9.9 due to inferior CD34+ vs. MNC ratio. Conclusion. The results obtained suggest that well–timed LVL–apheresis increased SC–yield in cell harvest, resulting in faster bone marrow repopulation and hematological reconstitution, as well as better overall clinical outcome of transplantation. These results necessitate additional examinations of CD34+ subsets ratio in cell harvest.
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Date Issued: 2008
PURL: http://purl.flvc.org/fau/fd/FAUIR000042
Format: Citation

Title: Convexities move because they contain matter.
Creator: Barenholtz, Elan
Date Issued: 2010-09-22
PURL: http://purl.flvc.org/fau/fd/FAUIR000120
Format: Citation

Title: Figure-ground assignment to a translating contour: A preference for advancing vs. receding motion.
Creator: Barenholtz, Elan, Tarr, M. J.
Date Issued: 2009-05-01
PURL: http://purl.flvc.org/fau/fd/FAUIR000119
Format: Citation

Title: Intrinsic and contextual features in object recognition.
Creator: Schlangen, Derrick, Barenholtz, Elan
Date Issued: 2015-01-28
PURL: http://purl.flvc.org/fau/fd/FAUIR000188
Format: Citation

Title: Measurement of the Doppler shift in forward-scattered waves caused by moderate sea surface motion in shallow waters.
Creator: Beaujean, Pierre-Philippe, Strutt, Guenael T.
Abstract/Description: A study of the impulse response of the acoustic channel in shallow waters is presented with respect to space, time, and frequency shift over a time window of two hours. A broadband chirp (42–54 kHz) and a narrow band sine wave (58 kHz) are transmitted from a static source located at 51 and 166 m from a vertical line receiver array. In 20 m of water with 0.4 m of wave height, an average Doppler shift of 20 Hz is measured at 51 m range, and 10 Hz at 166 m range, due to the sea-surface motion.
Date Issued: 2005-10
PURL: http://purl.flvc.org/fau/fd/FAUIR000001
Format: Citation

Title: Determining habitat quality for species that demonstrate dynamic habitat selection.
Creator: Beerens, James M., Frederick, Peter C., Noonburg, Erik G., Gawlik, Dale E.
Date Issued: 2015-11-19
PURL: http://purl.flvc.org/fau/fd/FAUIR000141
Format: Citation

Title: Linking Dynamic Habitat Selection with Wading Bird Foraging Distributions across Resource Gradients.
Creator: Beerens, James M., Noonburg, Erik G., Gawlik, Dale E., Gao, Chang-Qing
Date Issued: 2015-06-24
PURL: http://purl.flvc.org/fau/fd/FAUIR000142
Format: Citation

Title: Pushing the limit: Examining factors that affect anoxia tolerance in a single genotype of adult D. melanogaster.
Creator: Benasayag Meszaros, Raquel, Risley, Monica G., Hernandez, Priscilla, Fendrich, Margo, Dawson-Scully, Ken
Abstract/Description: Drosophila melanogaster is a promiscuous species that inhabits a large range of harsh environments including flooded habitats and varying temperature changes. To survive these environments, fruit flies have adapted mechanisms of tolerance that allow them to thrive. During exposure to anoxic stress, fruit flies and other poikilotherms enter into a reversible, protective coma. This coma can be manipulated based on controlled environmental conditions inside the laboratory. Here we utilize a...
Show moreDrosophila melanogaster is a promiscuous species that inhabits a large range of harsh environments including flooded habitats and varying temperature changes. To survive these environments, fruit flies have adapted mechanisms of tolerance that allow them to thrive. During exposure to anoxic stress, fruit flies and other poikilotherms enter into a reversible, protective coma. This coma can be manipulated based on controlled environmental conditions inside the laboratory. Here we utilize a common laboratory raised strain of D. melanogaster to characterize adaptation abilities to better understand coma recovery and survival limitations. Our goal is to mimic the fly’s natural environments (wet anoxia) and relate findings to a typical gas induced environment (dry anoxia) that is commonly used in a laboratory. Despite the abundance of research regarding acute and chronic anoxic exposure and cold stress, the literature is lacking evidence linking anoxic stress with variable environmental conditions such as animal age and stress duration. We present novel ways to assess coma recovery and survival using readily available laboratory tools. Our findings suggest that younger age, exposure to colder temperatures and wet environments increase resistance to anoxic stress.
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Date Issued: 2015-08-17
PURL: http://purl.flvc.org/fau/fd/FAUIR000065
Format: Citation

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