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Indications ofrelationships between poriferan classes using full-length 18S rRNA gene sequences
Title
Indications ofrelationships between poriferan classes using full-length 18S rRNA gene sequences.
Creator
Adams, Christi L., McInerney, James O., Kelly-Borges, M., Harbor Branch Oceanographic Institute
Date Issued
1999
PURL
http://purl.flvc.org/fau/fd/FA00007272
Subject Headings
Sponges, RNA, Ribosomal, 18S, Demospongiae, Phylogeny--Molecular aspects, Calcarea, Hexactinellida
Format
Document (PDF)
Influence of sponges on invertebrate recruitment: a field test of allelopathy
Title
Influence of sponges on invertebrate recruitment: a field test of allelopathy.
Creator
Bingham, Brian L., Young, Craig M., Harbor Branch Oceanographic Institute
Date Issued
1991
PURL
http://purl.flvc.org/FCLA/DT/3333176
Subject Headings
Allelopathy, Sponges, Invertebrates
Format
Document (PDF)
Isobatzellines A, B, C, and D. Cytotoxic and antifungal pyrroloquinoline alkaloids from the marine sponge Batzella sp.
Title
Isobatzellines A, B, C, and D. Cytotoxic and antifungal pyrroloquinoline alkaloids from the marine sponge Batzella sp.
Creator
Sun, H. H., Sakemi, S., Burres, N. S., McCarthy, Peter J.
Date Issued
1990
PURL
http://purl.flvc.org/FCLA/DT/3332970
Subject Headings
Sponges, Alkaloids, Pyrroles, Quinolines, Poecilosclerida
Format
Document (PDF)
Isolation and characterization of niphatevirin, a human-immunodeficiency-virus-inhibitory glycoprotein from the marine sponge Niphates erecta.
Title
Isolation and characterization of niphatevirin, a human-immunodeficiency-virus-inhibitory glycoprotein from the marine sponge Niphates erecta.
Creator
O'Keefe, Barry R., Beutler, John A., Cardellina, John H., II, Gulakowski, Robert J., Krepps, Benjamin L., McMahon, James B., Sowder, Raymond C., II, Henderson, Louis E., Pannell, Lewis K., Pomponi, Shirley A., Boyd, Michael R.
Date Issued
1997
PURL
http://purl.flvc.org/FCLA/DT/3174088
Subject Headings
Sponges, Sponges--Anatomy
Format
Document (PDF)
Isolation and structure elucidation of 34-sulfatobastadin 13, an inhibitor of the endothelin A receptor, from a marine sponge of the genus Ianthella
Title
Isolation and structure elucidation of 34-sulfatobastadin 13, an inhibitor of the endothelin A receptor, from a marine sponge of the genus Ianthella.
Creator
Gulavita, N. K., Wright, Amy E., McCarthy, Peter J., Pomponi, Shirley A., Kelly-Borges, M., Chin, M., Sills, Matthew A.
Date Issued
1993
PURL
http://purl.flvc.org/FCLA/DT/3333007
Subject Headings
Sponges, Receptor, Endothelin A, Marine natural products, Anti-Infective Agents
Format
Document (PDF)
Isolation and structure elucidation of novel compounds from marine cyanobacteria
Title
Isolation and structure elucidation of novel compounds from marine cyanobacteria.
Creator
Meickle, Theresa, Charles E. Schmidt College of Science, Department of Chemistry and Biochemistry
Abstract/Description
The work of this dissertation examined the secondary metabolites of several blooms of the marine cyanobacterium Lyngbya collected in Guam and Florida with an emphasis on the isolation and structure elucidation of novel biologically active compounds. The introduction in Chapter One provides a brief history of marine natural products, a description of cyanobacteria and a summary of peptides isolated from Lyngbya collected in the Caribbean. In Chapter Two, a bioassay-guided fractionation of a...
Show moreThe work of this dissertation examined the secondary metabolites of several blooms of the marine cyanobacterium Lyngbya collected in Guam and Florida with an emphasis on the isolation and structure elucidation of novel biologically active compounds. The introduction in Chapter One provides a brief history of marine natural products, a description of cyanobacteria and a summary of peptides isolated from Lyngbya collected in the Caribbean. In Chapter Two, a bioassay-guided fractionation of a Floridian collection of Lyngbya polychroa led to the isolation and structural determination of the cytotoxin desacetylmicrocolin B and the known compounds microcolins A and B. The structures were established by nuclear magnetic resonance (NMR) spectroscopic analysis. All three compounds inhibited the growth of cancer cell lines HT-29 and IMR-32 at nanomolar concentrations. Microcolins A and B were found to have little activity in the ecological assay against the marine fungus Dendryphiella salina. Chapter Three describes the isolation and structure elucidation of the glycosidic, acyl proline derivative tumonoic acid J from a sample Lyngbya sp. collected in Guam. The planar structure was determined by 1D and 2D NMR spectroscopy in conjunction with high resolution-mass spectrometry (HR-MS) data. Tumonoic acid J showed moderate activity in the ecological assay against the marine fungus D. salina. In Chapter Four, NMR-guided fractionation of a Floridian sample of Lyngbya majuscula led to the isolation of two novel cyclic peptides porpoisamides A and B. The planar structures were determined by 1D and 2D NMR spectroscopy with HR-MS data. The absolute configurations of these two compounds were defined through chiral chromatographic methods and derivatization techniques., The porpoisamides showed only moderate activity in cytotoxicity assays against cancer cell lines HCT-116 and U2OS. Finally, Chapter Five examines a potential ecological role of compounds isolated from marine cyanobacte ria. These secondary metabolites may function as chemical defenses against competing microorganisms within marine environments. Compounds isolated from cyanobacteria were tested for anti-fungal activity against the saprophytic marine fungus D. salina. Three of the six compounds tested produced inhibitory activity at or below their natural concentration.
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Date Issued
2010
PURL
http://purl.flvc.org/FAU/2978991
Subject Headings
Sponges, Ecology, Cyanobacteria, Biological control, Aquatic ecology
Format
Document (PDF)
Isolation and structure elucidation of onnamide a, a new bioactive metabolite of a marine sponge, Theonella sp.
Title
Isolation and structure elucidation of onnamide a, a new bioactive metabolite of a marine sponge, Theonella sp.
Creator
Sakemi, S., Ichiba, T., Kohmoto, S., Saucy, G., Higa, T., Harbor Branch Oceanographic Institute
Date Issued
1988
PURL
http://purl.flvc.org/FCLA/DT/3332945
Subject Headings
Sponges, Bioactive compounds, Marine metabolites, Marine Toxins
Format
Document (PDF)
Isolation and structure elucidation of Perthamide B, a novel peptide from the sponge Theonella sp.
Title
Isolation and structure elucidation of Perthamide B, a novel peptide from the sponge Theonella sp.
Creator
Gulavita, N. K., Pomponi, Shirley A., Wright, Amy E., Yarwood, Donna, Sills, Matthew A.
Date Issued
1994
PURL
http://purl.flvc.org/FCLA/DT/3331880
Subject Headings
Sponges, Cyclic peptides, Peptides--Structure, Spectroscopic techniques
Format
Document (PDF)
Isolation of Latrunculin A, 6,7-Epoxylatrunculin A, Fijianolide A, and Euryfuran from a new genus of the family Thorectidae
Title
Isolation of Latrunculin A, 6,7-Epoxylatrunculin A, Fijianolide A, and Euryfuran from a new genus of the family Thorectidae.
Creator
Gulavita, N. K., Gunasekera, Sarath P., Pomponi, Shirley A.
Date Issued
1992
PURL
http://purl.flvc.org/FCLA/DT/3332996
Subject Headings
Sponges, Marine toxins, Marine metabolites
Format
Document (PDF)
Isometachromin, a new cytotoxic sesquiterpenoid from a deep water sponge of the family Spongiidae
Title
Isometachromin, a new cytotoxic sesquiterpenoid from a deep water sponge of the family Spongiidae.
Creator
McConnell, O. J., Longley, Ross E., Gunasekera, M., Harbor Branch Oceanographic Institute
Date Issued
1992
PURL
http://purl.flvc.org/fau/fd/FA00007220
Subject Headings
Sponges, Sesquiterpenes, Cytotoxins, Porifera
Format
Document (PDF)
Kauluamine: an unprecedented manzamine dimer from an Indonesian marine sponge, Prianos sp
Title
Kauluamine: an unprecedented manzamine dimer from an Indonesian marine sponge, Prianos sp.
Creator
Ohtani, I. I., Ichiba, T., Isobe, M., Kelly-Borges, M., Scheuer, P. J., Harbor Branch Oceanographic Institute
Date Issued
1995
PURL
http://purl.flvc.org/FCLA/DT/3319093
Subject Headings
Sponges, Sponges --Research, Marine natural products, Alkaloids
Format
Document (PDF)
Kumusine, a chloroadenine riboside from a sponge, Theonella sp.
Title
Kumusine, a chloroadenine riboside from a sponge, Theonella sp.
Creator
Ichiba, T., Nakao, Y., Scheuer, P. J., Noriko, U. S., Kelly-Borges, M., Harbor Branch Oceanographic Institute
Date Issued
1995
PURL
http://purl.flvc.org/FCLA/DT/3331896
Subject Headings
Sponges, Nucleosides
Format
Document (PDF)
Lasonolides C—G, Five New Lasonolide Compounds from the Sponge Forcepia sp.
Title
Lasonolides C—G, Five New Lasonolide Compounds from the Sponge Forcepia sp.
Creator
Wright, Amy E., Chen, Ying, Winder, Priscilla L., Pitts, Tara P., Pomponi, Shirley A., Longley, Ross E.
Date Issued
2004
PURL
http://purl.flvc.org/FCLA/DT/3164109
Subject Headings
Macrolide antibiotics, Natural products, Mass spectrometry, Sponges, Stereochemistry
Format
Document (PDF)
Leiodermatolide, a potent antimitotic macrolide from the marine sponge Leiodermatium sp.
Title
Leiodermatolide, a potent antimitotic macrolide from the marine sponge Leiodermatium sp.
Creator
Paterson, Ian, Dalby, S. M., Roberts, J. C., Naylor, G. J., Guzman, Esther A., Isbrucker, Richard A., Pitts, Tara P., Linley, P. A., Divlianska, D. B., Reed, John K., Wright, Amy E.
Date Issued
2011
PURL
http://purl.flvc.org/fau/fd/FA00007465
Subject Headings
Antimitotic Agents, Macrolides, Sponges, Molecular structure, Nuclear Magnetic Resonance, Biomolecular, Cell lines
Format
Document (PDF)
Limits on the bathymetric distribution ofkeratose sponges: a field test in deep water.
Title
Limits on the bathymetric distribution ofkeratose sponges: a field test in deep water.
Creator
Maldonado, Manuel, Young, Craig M., Harbor Branch Oceanographic Institute
Date Issued
1998
PURL
http://purl.flvc.org/fau/fd/FA00007237
Subject Headings
Sponges, Sponges--Ecology, Symbiosis, Demospongiae
Format
Document (PDF)
Makaluvamine G, a cytotoxic pigment from an Indonesian sponge Histodermella sp.
Title
Makaluvamine G, a cytotoxic pigment from an Indonesian sponge Histodermella sp.
Creator
Carney, J. R., Scheuer, P. J., Kelly-Borges, M., Harbor Branch Oceanographic Institute
Date Issued
1993
PURL
http://purl.flvc.org/FCLA/DT/3331874
Subject Headings
Sponges, Cytotoxin, Tryptamine--Derivatives--Synthesis, Tyramine, Antineoplastic agents
Format
Document (PDF)
Manzamine A, a novel antitumor alkaloid from a sponge
Title
Manzamine A, a novel antitumor alkaloid from a sponge.
Creator
Sakai, R., Higa, T., Jefford, C. W., Bernardinelli, G., Harbor Branch Oceanographic Institute
Date Issued
1986
PURL
http://purl.flvc.org/FCLA/DT/3332936
Subject Headings
Alkaloids, Antineoplastic agents, Carbazoles, Sponges
Format
Document (PDF)
Manzamine B and C, two novel alkaloids from the sponge Haliciona sp
Title
Manzamine B and C, two novel alkaloids from the sponge Haliciona sp.
Creator
Sakai, R., Kohmoto, S., Higa, T., Jefford, C. W., Bernardinelli, G., Harbor Branch Oceanographic Institute
Date Issued
1987
PURL
http://purl.flvc.org/FCLA/DT/3353812
Subject Headings
Indole Alkaloids, Sponges, Carbolines
Format
Document (PDF)
Marine sponge Bis(Indole) alkaloids that displace ligand binding to α1 adrenergic receptors
Title
Marine sponge Bis(Indole) alkaloids that displace ligand binding to α1 adrenergic receptors.
Creator
Phife, D. W., Ramos, R. A., Feng, M., King, I., Gunasekera, Sarath P., Wright, Amy E., Patel, Mahesh, Pachter, J. A., Coval, S. J.
Date Issued
1996
PURL
http://purl.flvc.org/FCLA/DT/3331919
Subject Headings
Sponges, Indole alkaloids, Adrenergic alpha blockers, Alpha adrenoceptors, Ligand binding (Biochemistry)
Format
Document (PDF)
Microxine, a New cdc2 Kinase Inhibitor from the Australian MarinE Sponge Microxina Species
Title
Microxine, a New cdc2 Kinase Inhibitor from the Australian MarinE Sponge Microxina Species.
Creator
Killday, K. B., Yarwood, Donna, Sills, Matthew A., Murphy, Peter T., Hooper, J. N. A., Wright, Amy E.
Date Issued
2001
PURL
http://purl.flvc.org/FCLA/DT/3164092
Subject Headings
Sponges, Chromatographic analysis, Spectrum analysis, Phosphoprotein Phosphatase --analysis, Nucleosides
Format
Document (PDF)

Pages