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You’ve got to keep ‘em separated: characterizing lagging chromosome prevention in oral cancer cells
Title
You’ve got to keep ‘em separated: characterizing lagging chromosome prevention in oral cancer cells.
Creator
Beltran, Rosa Nathalie, Quintyne, Nicholas, Harriet L. Wilkes Honors College
Abstract/Description
Mitosis is the separation of duplicated chromosomes into two daughter cells in order to create viable offspring. There are many checks in mitosis to ensure the inherited chromosome number is correct. Sometimes, these checkpoints are overcome and daughter cells inherit defects which can lead to cancer. One defect is the appearance of lagging chromosomes, the result of inaccurate chromosomal separation which leads to incorrect chromosome number termed aneuploidy. Aneuploidy is one of the...
Show moreMitosis is the separation of duplicated chromosomes into two daughter cells in order to create viable offspring. There are many checks in mitosis to ensure the inherited chromosome number is correct. Sometimes, these checkpoints are overcome and daughter cells inherit defects which can lead to cancer. One defect is the appearance of lagging chromosomes, the result of inaccurate chromosomal separation which leads to incorrect chromosome number termed aneuploidy. Aneuploidy is one of the defining traits of cancerous cells. The potential mechanism of lagging chromosomes in the cancerous cell line UPCI:OSCC070 is investigated in this study. siRNA-induced knockdown of KIFC1, a protein that is involved in the centrosomal clustering to prevent multipolar spindles, was used in the cells. Examining both levels of knockdown and time of exposure, we saw that the loss of KIFC1 led to a significant increase in lagging chromosomes, indicating this protein is critical to proper mitotic progression.
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Date Issued
2013
PURL
http://purl.flvc.org/fau/fd/FA00003505
Format
Document (PDF)
You're too late!"
Title
" You're too late!": prenatal health seeking behaviors of Guatemalan Mayan women in Palm Beach County.
Creator
Supanich, Colleen., Dorothy F. Schmidt College of Arts and Letters, Department of Anthropology
Abstract/Description
In this thesis I explore the circumstances in which pregnant Guatemalan Mayan women in South Florida communities found themselves. A local non-profit organization, the Guatemalan Maya Center (GMC), offered assistance to pregnant Mayan women to secure biomedical prenatal care, yet many continued to underutilize these services. The decision to utilize this form of care largely depended on whether a woman received care from a traditional midwife in the community. Women receiving care from a...
Show moreIn this thesis I explore the circumstances in which pregnant Guatemalan Mayan women in South Florida communities found themselves. A local non-profit organization, the Guatemalan Maya Center (GMC), offered assistance to pregnant Mayan women to secure biomedical prenatal care, yet many continued to underutilize these services. The decision to utilize this form of care largely depended on whether a woman received care from a traditional midwife in the community. Women receiving care from a midwife generally did not seek biomedical care until late in their pregnancies. Women unable to locate a midwife often incorporated biomedical care once they suspected pregnancy. Due to the difficulties accessing the GMC's services prior to enrollment many of these women did not obtain "timely" care. A better understanding of the ways in which Guatemalan Mayan women incorporated biomedical prenatal care into their lives is the first step towards increasing their participation in these services.
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Date Issued
2009
PURL
http://purl.flvc.org/FAU/192990
Subject Headings
Maya women, Medical care, Prenatal care, Maternal health services, Midwifery, Social aspects, Migrant agricultural laborers, Medical care
Format
Document (PDF)
You should be ashamed of yourself
Title
You should be ashamed of yourself: a study of moral development and moral emotion.
Creator
Bright, Justin., Harriet L. Wilkes Honors College
Abstract/Description
Research on Kohlberg's theory of moral development has examined moral development by examining individuals' justice operations. However, how the moral emotions are related to moral development has been neglected. In a sample of mostly undergraduates (N=53), moral development (measured using an index of higher-level moral reasoning and one of reasoning consistency from the Defining Issues Test) and the moral emotions of guilt, shame, empathy, and self-esteem were measured. Shame was positively...
Show moreResearch on Kohlberg's theory of moral development has examined moral development by examining individuals' justice operations. However, how the moral emotions are related to moral development has been neglected. In a sample of mostly undergraduates (N=53), moral development (measured using an index of higher-level moral reasoning and one of reasoning consistency from the Defining Issues Test) and the moral emotions of guilt, shame, empathy, and self-esteem were measured. Shame was positively related to higher moral reasoning (r=.26, p<.10); guilt was not (r=-.02, ns). Empathy was also positively correlated with higher moral reasoning (r=.19). Moral consistency was positively related to shame (r=.31, p<.05) and guilt (r=.32, p<.05). Existential theory was used to explain the differentiation between shame and guilt in their correlations with higher moral reasoning. The correlations between moral consistency and guilt and between moral consistency and shame are discussed with respect to the inhibitive nature of shame and guilt.
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Date Issued
2008
PURL
http://purl.flvc.org/FAU/77659
Subject Headings
Moral development, Social ethics, Emotions, Moral and ethical aspects, Emotions and cognition
Format
Document (PDF)
You R Cute: The Influence Of Societal Perception On The Search For Online Romantic Partners
Title
You R Cute: The Influence Of Societal Perception On The Search For Online Romantic Partners.
Creator
DiPiero, Samantha, Lanning, Kevin, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description
While online dating is very convenient, it causes an evolutionary mismatch, our ancestors did not have websites to search for partners. However, there are some similarities that can be seen between current and ancestral times in relation to societal perception, especially in relation to parental investment theory. Using an OkCupid dataset of 2620 questions, 166 were selected in order to evaluate how much of an influence societal perception ( the influence of family and friends, substance use,...
Show moreWhile online dating is very convenient, it causes an evolutionary mismatch, our ancestors did not have websites to search for partners. However, there are some similarities that can be seen between current and ancestral times in relation to societal perception, especially in relation to parental investment theory. Using an OkCupid dataset of 2620 questions, 166 were selected in order to evaluate how much of an influence societal perception ( the influence of family and friends, substance use, education, stigma, religion, appearance, and morals) has on searching for a romantic partner. The data was evaluated in four separate stages: Initially just 100 cases were examined to reduce computational burden, then an additional 2000 were used to look at the structure of key variables. Of the remaining cases, 60% were used to develop a prediction model and 40% to test this model. It was found that women tended to be more selective on six of the seven scales that were measured, this selectiveness can be attributed to parental investment theory. significant influence in revolutionary politics through agricultural and industrial collectivization, communes, militia resistance, and participation in government. Many historians have explained anarchism through the lens of ideology, a doctrine based upon a structure of authority. This thesis, however, explains anarchist power and unity during the Spanish Civil War as a matter of identity, as a meaningful sense of self. Spanish anarchists defined themselves through the process of negation – the act of defining who you are by defining what you are not – by their opposition to authority, to religion, to feudalism, to capitalism and fascism, to communism, and to anarchism. The anarchists also affirmed who they were as individuals and as communities through three values: yearning for absolute freedom, the capacity for absolute fraternity removed from centralized authority, and absolute egalitarianism – the unreserved equality of all individuals.
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Date Issued
2018
PURL
http://purl.flvc.org/fau/fd/FAUHT00011
Format
Document (PDF)
You keep me hangin' on
Title
You keep me hangin' on: dynactin's p24 is essential for microtube anchoring.
Creator
Le, Ariel., Harriet L. Wilkes Honors College
Abstract/Description
Dynactin is a multisubunit protein complex that functions as a processivity cofactor to cytoplasmic dynein, assisting in vesicle transport and cell division. Independent of dynein,dynactin also serves to anchor microtubules to the centrosome. The functions of the majority of dynactin's subunits have been described to a certain degree ; however, the p24 subunit remains largely uncharacterized. Among the few things that are known about p24 are that it has a predicted molecular weight of about...
Show moreDynactin is a multisubunit protein complex that functions as a processivity cofactor to cytoplasmic dynein, assisting in vesicle transport and cell division. Independent of dynein,dynactin also serves to anchor microtubules to the centrosome. The functions of the majority of dynactin's subunits have been described to a certain degree ; however, the p24 subunit remains largely uncharacterized. Among the few things that are known about p24 are that it has a predicted molecular weight of about 20,822 Da, forms an a-helix, and binds directly to the p150[Glued] subunit. In order to explore its function further, we have performed shRNA-mediated knockdown, and fluorescent microscopy. We observe that microtubule disorganization is amplified due to the loss of p24. Our findings support the model that p24 serves as reinforcement to stabilize p150[Glued] at the centrosome.
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Date Issued
2012
PURL
http://purl.flvc.org/FAU/3355592
Subject Headings
Cytoskeletal proteins, Cell organellles, Formation, Microtubules, Molecular biology
Format
Document (PDF)
YOU CAN STILL FALL IN LOVE AT THE END OF THE WORLD
Title
YOU CAN STILL FALL IN LOVE AT THE END OF THE WORLD.
Creator
Buijk, Cherri, McKay, Becka, Florida Atlantic University, Department of English, Dorothy F. Schmidt College of Arts and Letters
Date Issued
2020
PURL
http://purl.flvc.org/fau/fd/FA00013464
Subject Headings
Creative writing, Fiction
Format
Document (PDF)
You Are Lost
Title
You Are Lost.
Abstract/Description
Cartoon depiction of man labelled North offering a pole with the US flag to a man fallen into water and about to be eaten by an alligator labelled Secession. Caption reads: I say old fellow just hold on to this ere flag or "YOU ARE LOST"
PURL
http://purl.flvc.org/fcla/dt/3171543
Subject Headings
Prints, American –19the century, United States --History –Civil War, 1861-1865 –Pictorial Works, Confederate States of America –History –Pictorial works, United States –History –Civil War, 1861-1865 –Art and the war, Caricatures and cartoons -- United States
Format
Image (JPEG2000)
Yosele
Title
Yosele.
Creator
Asch, Sholem 1880-1957
Date Issued
1921
PURL
http://purl.flvc.org/fau/2975648
Subject Headings
Children's literature, Yiddish
Format
Document (PDF)
Yosel and Schmendrik's Kalle
Title
Yosel and Schmendrik's Kalle.
Creator
Kammen, Jack, Kammen, Joseph, Gilrod, Louis
Abstract/Description
FAU Libraries Print Music Collection dates from circa 1890-present and includes original manuscripts from renowned, non-living Jewish composers, handwritten music from American and European-born cantors, and rare—if not sole-surviving—scores from major American Jewish publishing houses no longer in existence. It also houses one of the nation’s largest collections of American Yiddish theater music, comprised of piano-vocal scores spanning the years 1890-1960. This digital collection contains...
Show moreFAU Libraries Print Music Collection dates from circa 1890-present and includes original manuscripts from renowned, non-living Jewish composers, handwritten music from American and European-born cantors, and rare—if not sole-surviving—scores from major American Jewish publishing houses no longer in existence. It also houses one of the nation’s largest collections of American Yiddish theater music, comprised of piano-vocal scores spanning the years 1890-1960. This digital collection contains select pieces from the FAU Libraries Print Music Collection.
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PURL
http://purl.flvc.org/fau/fd/FA00003364
Subject Headings
Violin Part
Format
Document (PDF)
Yosef un zayne brider
Title
Yosef un zayne brider.
Creator
Moud, Z.
Date Issued
1918
PURL
http://purl.flvc.org/fau/2866576
Subject Headings
Children's literature, Yiddish
Format
Document (PDF)
Yokhim Ber
Title
Yokhim Ber.
Creator
Seton, Ernest Thompson 1860-1946, Kaplan, Pesaḥ 1870-1943, Rubinstein, M.
Date Issued
1921
PURL
http://purl.flvc.org/fau/2979372
Subject Headings
Children's literature, Yiddish, Baer, Joachim T.
Format
Document (PDF)
Yismechu
Title
Yismechu.
Creator
Ellstein, Abraham
Date Issued
1963
PURL
http://purl.flvc.org/fau/fd/FA00003381
Format
Document (PDF)
Yisgadal
Title
Yisgadal.
Creator
Rosenblatt, Yossele
PURL
http://purl.flvc.org/fcla/dt/3361894
Subject Headings
Piano, Voice, Solo, Secular genre
Format
Document (PDF)
Yiftah
Title
Yiftah.
Creator
Pat, Jacob
Date Issued
1920
PURL
http://purl.flvc.org/fau/fd/FA00000232
Format
Document (PDF)
Yidishkeit
Title
Yidishkeit.
Creator
Olshanetsky, Alexander, Jacobs, J.
Abstract/Description
FAU Libraries Print Music Collection dates from circa 1890-present and includes original manuscripts from renowned, non-living Jewish composers, handwritten music from American and European-born cantors, and rare—if not sole-surviving—scores from major American Jewish publishing houses no longer in existence. It also houses one of the nation’s largest collections of American Yiddish theater music, comprised of piano-vocal scores spanning the years 1890-1960. This digital collection contains...
Show moreFAU Libraries Print Music Collection dates from circa 1890-present and includes original manuscripts from renowned, non-living Jewish composers, handwritten music from American and European-born cantors, and rare—if not sole-surviving—scores from major American Jewish publishing houses no longer in existence. It also houses one of the nation’s largest collections of American Yiddish theater music, comprised of piano-vocal scores spanning the years 1890-1960. This digital collection contains select pieces from the FAU Libraries Print Music Collection.
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PURL
http://purl.flvc.org/fau/fd/FA00003363
Subject Headings
Voice and Piano
Format
Document (PDF)
Yidelech Breederlech
Title
Yidelech Breederlech.
Creator
Friedsell, Louis
Date Issued
1905
PURL
http://purl.flvc.org/FCLA/DT/71916
Subject Headings
Piano, Voice, Solo, Secular genre
Format
Document (PDF)
Yiddishe Kroin
Title
Yiddishe Kroin.
Creator
Perlmutter & Wohl, Thomashefsky, B.
Date Issued
1921
PURL
http://purl.fcla.edu/fcla/dt/57326
Subject Headings
Piano, Voice, Secular genre
Format
Document (PDF)
Yiddish Marseillaise
Title
Yiddish Marseillaise.
Creator
Russotto, Henry A., Schreiber, F.
Date Issued
1910
PURL
http://purl.flvc.org/FCLA/DT/70742
Subject Headings
Piano, Voice, Solo, Secular genre
Format
Document (PDF)
Yesterday Will Come
Title
Yesterday Will Come.
Creator
D'Sa, Meryl, McKay, Becka, Florida Atlantic University, Dorothy F. Schmidt College of Arts and Letters, Department of English
Abstract/Description
Yesterday Will Come is a hybrid collection of linked short stories that focuses on the way a particular family passes down the family history through physical and emotional memories. The collection largely focuses on the process of making and preserving memories and how the lack of control over one’s memory can lead to paranoia and displacement in their life. Particular value is attached to certain memories and the value and emotion attached can at times overwrite the actual content of the...
Show moreYesterday Will Come is a hybrid collection of linked short stories that focuses on the way a particular family passes down the family history through physical and emotional memories. The collection largely focuses on the process of making and preserving memories and how the lack of control over one’s memory can lead to paranoia and displacement in their life. Particular value is attached to certain memories and the value and emotion attached can at times overwrite the actual content of the memory. The stories center around the Riviera family and particularly Ana Riviera’s life as she considers the many aspects of her family history she continues to inherit and the comfort and paranoia she associates with such inheritance.
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Date Issued
2019
PURL
http://purl.flvc.org/fau/fd/FA00013200
Subject Headings
Short stories, Creative writing, Family history
Format
Document (PDF)
Yes Douglas Husak, Drunk Driving is a Serious Offense.
Title
Yes Douglas Husak, Drunk Driving is a Serious Offense.
Creator
Kurland, Brittany, Tunick, Mark, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description
Drunk driving is a serious offense, but often goes unnoticed because no harm is often caused by the person committing such a selfish act. Where there is an accident, fatal or minor, the individual is punished for driving while intoxicated. While many theorists believe that it is inappropriate to punish one who has a blood alcohol concentration (BAC) over the legal limit of .08%, I propose that regardless of the individual harming or not harming another, the person who is driving while...
Show moreDrunk driving is a serious offense, but often goes unnoticed because no harm is often caused by the person committing such a selfish act. Where there is an accident, fatal or minor, the individual is punished for driving while intoxicated. While many theorists believe that it is inappropriate to punish one who has a blood alcohol concentration (BAC) over the legal limit of .08%, I propose that regardless of the individual harming or not harming another, the person who is driving while intoxicated should face punishment. It should not matter if the driver did not show any signs of impairment or if they hurt anyone else while driving. Any person that goes behind the wheel impaired is at greater risk for hurting themselves or someone else at that time.
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Date Issued
2020
PURL
http://purl.flvc.org/fau/fd/FA00003713
Format
Document (PDF)

Pages