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- Title
- Use Of Molecular Techniques To Understand The Spatial And Temporal Features Of The Oceanic Stage In Hawksbill Sea Turtles, Eretmochelys Imbricata; A Thesis Proposal.
- Creator
- Coppenrath, Christina, Salmon, Michael, Graduate College
- Abstract/Description
-
For highly migratory species, it is important to understand what habitats are used and what requirements are essential for growth and development. These migrations often span different political and regulatory boundaries, complicating conservation strategies. The hatchlings and post-hatchlings of most sea turtle species migrate to oceanic habitats where they remain for several years before returning to shallow developmental habitats. For critically endangered hawksbill turtle, Eretmochelys...
Show moreFor highly migratory species, it is important to understand what habitats are used and what requirements are essential for growth and development. These migrations often span different political and regulatory boundaries, complicating conservation strategies. The hatchlings and post-hatchlings of most sea turtle species migrate to oceanic habitats where they remain for several years before returning to shallow developmental habitats. For critically endangered hawksbill turtle, Eretmochelys imbricata, most research has concentrated on nesting ecology and very little is known about the posthatchling migration. Many sea turtles then spend years in different foraging habitats before reaching sexual maturity, and such foraging grounds typically represent a mixed stock of turtles from different nesting beaches. Mitochondrial DNA analysis can be used to estimate genetic stock structure of mixedstock foraging populations for sea turtles, and the duration of the post-hatchling oceanic stage can be estimated using stable isotope analysis and satellite telemetry. Our objectives are to determine the duration of the post-hatchling oceanic stage of development, to determine if the turtles sampled in a particular foraging habitat represent a biased or unbiased assortment of matrilineages, and to infer potential migratory pathways by investigating ocean currents between nesting beaches and the foraging site. Here we discuss our methods, to determine the duration of the post-hatchling oceanic stage and stock structure for immature hawksbills at a developmental foraging ground.
Show less - Date Issued
- 2015
- PURL
- http://purl.flvc.org/fau/fd/FA00005873
- Format
- Document (PDF)
- Title
- Use of Drosophila melanogaster larvae to evaluate cardioactive peptides.
- Creator
- Alishaev, Zahava, Godenschwege, Tanja A., Mari, Frank
- Abstract/Description
-
Conopeptides are found in the venom of marine cone snails, aiding in the paralysis of their prey, and have been shown to have potential therapeutic uses in humans. Conopressins are conopeptides that target vasopressin/oxytocin receptors in vascular smooth muscle cells that are found within blood vessels. The crustacean cardioactive peptide (CCAP) is a homologous peptide found in crustaceans and has been shown to behave as a cardioaccelerator in a homologous system. This study describes the...
Show moreConopeptides are found in the venom of marine cone snails, aiding in the paralysis of their prey, and have been shown to have potential therapeutic uses in humans. Conopressins are conopeptides that target vasopressin/oxytocin receptors in vascular smooth muscle cells that are found within blood vessels. The crustacean cardioactive peptide (CCAP) is a homologous peptide found in crustaceans and has been shown to behave as a cardioaccelerator in a homologous system. This study describes the effects of CCAP in Drosophila larvae. We find that CCAP has an inotropic effect by causing a change in the contraction of blood vessels. We further investigate the effects of another possibly cardioactive conopeptide, γ-conopressin-vil, in Drosophila larvae. Elucidating the effects of conopetides in Drosophila larvae may translate to cardioactive therapeutic uses in mammalian systems.
Show less - Date Issued
- 2014
- PURL
- http://purl.flvc.org/fau/fd/FA0005000
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Urban Sprawl: The Invisible Destroyer of the Environment.
- Creator
- Gastineau, Megan, Holman, Mirya R., Dorothy F. Schmidt College of Arts and Letters
- Abstract/Description
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The purpose of this research is to inform Americans of what sprawl is and the negative effects it has on the environment. Sprawl is the unnecessary expansion of urban areas onto valuable unused land. In 2013, only 26% of Americans saw sprawl as a problem at all. Yet sprawl is the culprit behind better known issues, such as air pollution and water contamination. The increased use of vehicles and runoff makes sprawled out areas more polluted than compact cities. Because condensing a city is not...
Show moreThe purpose of this research is to inform Americans of what sprawl is and the negative effects it has on the environment. Sprawl is the unnecessary expansion of urban areas onto valuable unused land. In 2013, only 26% of Americans saw sprawl as a problem at all. Yet sprawl is the culprit behind better known issues, such as air pollution and water contamination. The increased use of vehicles and runoff makes sprawled out areas more polluted than compact cities. Because condensing a city is not a workable solution, another way is to improve public transportation. Places that have more sprawl force people to use cars. Improving public transportation by making it more accessible and reliable would encourage people to not use their cars, which saves them money and, in turn, causes less pollution.
Show less - Date Issued
- 2015
- PURL
- http://purl.flvc.org/fau/fd/FA00005190
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Urban Growth’s Effect on the Florida Everglades.
- Creator
- Sapienza, Valerie, Holman, Mirya R., Charles E. Schmidt College of Science
- Abstract/Description
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Urban growth, also known as urbanization or urban sprawl, is the spreading of metropolitan growth that consumes natural areas, which has many harmful effects on the environment. This study provides information on how urban growth is affecting the Florida Everglades in destructive ways, with a focus on the water in the Everglades. A plethora of water pollutants, such as phosphorous, nitrogen and mercury come directly from human activities associated with urban sprawl. This pollution affects...
Show moreUrban growth, also known as urbanization or urban sprawl, is the spreading of metropolitan growth that consumes natural areas, which has many harmful effects on the environment. This study provides information on how urban growth is affecting the Florida Everglades in destructive ways, with a focus on the water in the Everglades. A plethora of water pollutants, such as phosphorous, nitrogen and mercury come directly from human activities associated with urban sprawl. This pollution affects many parts of the Everglades’ natural ecosystem including sawgrass marshes and mangrove swamps, as well as endangered species, such as, the crocodile and Florida panther. This study also addresses limits on chemical pollution that can be placed by the President through executive orders. Overall, the water pollution in the Everglades is destructive in many ways and can be reduced through executive orders from the President to limit the use of chemicals in urban fringe areas.
Show less - Date Issued
- 2015
- PURL
- http://purl.flvc.org/fau/fd/FA00005208
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Understanding Sport-Related Concussions.
- Creator
- Coviello, Kassi, Nasrallah, Joseph, Escaleras, Monica, Levy, Eric
- Abstract/Description
-
In 2012, the amount of reported concussions doubled in the past ten years to 3.8 million. Concussions and head-related injuries caused by contact sports can lead to long term traumatic brain injuries. With the increasing presence of these injuries, the National Football League and the National Hockey League have implemented extensive concussion protocols. This questions the underlying uncertainty of the future of contact sports. Our project addresses the question of hypothetically, if you had...
Show moreIn 2012, the amount of reported concussions doubled in the past ten years to 3.8 million. Concussions and head-related injuries caused by contact sports can lead to long term traumatic brain injuries. With the increasing presence of these injuries, the National Football League and the National Hockey League have implemented extensive concussion protocols. This questions the underlying uncertainty of the future of contact sports. Our project addresses the question of hypothetically, if you had children, knowing what we know today about concussions/head related injuries, would you allow them to play contact sports. The decision to allow your child to play contact sports was motivated by the gender and age gap. The different levels of education had a statistically significant impact on the knowledge surrounding the current professional football and hockey concussion protocols.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000031
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Unconscious Plagiarism in Young and Older Adults.
- Creator
- Rowell, Shaina, Earles, Julie, Kersten, Alan, Tornopsky, C.
- Abstract/Description
-
FAU's Office of Undergraduate Research and Inquiry hosts an annual symposium where students engaged in undergraduate research may present their findings either through a poster presentation or an oral presentation.
- Date Issued
- 2011
- PURL
- http://purl.flvc.org/fau/fd/FA00005448
- Format
- Document (PDF)
- Title
- TruD's Effect On RNA Oxidation.
- Creator
- Mills, Darius, Martin, Narelle, Rodriguez, Gabriela, Li, Zhongwei
- Abstract/Description
-
Age-related neurodegenerative diseases impact society in an increasing rate. Oxidative damage to cellular molecules is considered the main cause of many neurological diseases such as, Alzheimer’s disease, Parkinson’s disease, etc. Understanding the mechanism and what cleans up oxidized molecules is vital in order to further explore therapeutic research for neurodegenerative diseases. RNA damage is potentially a major contributor to these diseases. However, compared to our knowledge about DNA,...
Show moreAge-related neurodegenerative diseases impact society in an increasing rate. Oxidative damage to cellular molecules is considered the main cause of many neurological diseases such as, Alzheimer’s disease, Parkinson’s disease, etc. Understanding the mechanism and what cleans up oxidized molecules is vital in order to further explore therapeutic research for neurodegenerative diseases. RNA damage is potentially a major contributor to these diseases. However, compared to our knowledge about DNA, little is known about the mechanism that cells use to eliminate damaged RNA. Our objective in this study is to understand the role of proteins that specifically bind oxidized RNA. We will focus on one such protein TruD in Escherichia coli. By studying how TruD and its mutants help E. coli to survive oxidative stress, we hope to elucidate a mechanism by which cells fight against RNA oxidation, and to suggest disease-preventing mechanisms by the human TruD homologs on a molecular level.
Show less - Date Issued
- 2014
- PURL
- http://purl.flvc.org/fau/fd/FA0005030
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Treatment Options for Mesial Temporal Lobe Epilepsy.
- Creator
- Melero, Blanca, Nevin, Angelica, Office of Undergraduate Research and Inquiry
- Abstract/Description
-
Mesial temporal lobe epilepsy (MTLE) is the most common form of epilepsy seen in adults. Most mesial temporal lobe epilepsy have an association with hippocampal sclerosis. Patients suffering from MTLE have had seizures or experienced a serious injury during critical brain growth periods of their childhood. Research to date on MTLE has not elicited the discovery of a pharmaceutical treatment. Therefore, MTLE is currently treatable through only surgery. Patients who are eligible for surgery are...
Show moreMesial temporal lobe epilepsy (MTLE) is the most common form of epilepsy seen in adults. Most mesial temporal lobe epilepsy have an association with hippocampal sclerosis. Patients suffering from MTLE have had seizures or experienced a serious injury during critical brain growth periods of their childhood. Research to date on MTLE has not elicited the discovery of a pharmaceutical treatment. Therefore, MTLE is currently treatable through only surgery. Patients who are eligible for surgery are already in the advanced stages of MTLE, although recently there has been a discovery that post surgery, has shown some risk of memory lost. Now, laser ablation therapy is being looked at as an alternative treatment for those who are suffering from MTLE. The focus of this study is on the current research on MTLE with a concentration on possible connections of the diagnosis and treatment options for patients experiencing different types of epilepsy.
Show less - Date Issued
- 2016
- PURL
- http://purl.flvc.org/fau/fd/FA00005590
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Travel-time Based Signal Performance Measures (TTSPM).
- Creator
- Petrovska, Natasha, Stevanovic, Aleksandar, Graduate College
- Abstract/Description
-
Vehicle travel time on arterial roads with signalized intersections is an essential parameter for traffic management. There is an increasing interest in signal performance measurement for signalized intersections in the United States. Reducing the journey times and increasing the capacity are some of the fundamental aims with potential benefits in environmental pollution, and energy utilization. The Travel-time Based Signal Performance Measures application is a tool for estimating signal...
Show moreVehicle travel time on arterial roads with signalized intersections is an essential parameter for traffic management. There is an increasing interest in signal performance measurement for signalized intersections in the United States. Reducing the journey times and increasing the capacity are some of the fundamental aims with potential benefits in environmental pollution, and energy utilization. The Travel-time Based Signal Performance Measures application is a tool for estimating signal performance measures based on upstream-link travel times. The application utilizes well known concept of Volume- Delay Functions to convert measured travel times into signal performance measures. Based on this functionality, it can estimate the performance measures for 7 signalized intersections on Glades Road, Boca Raton, Florida. Available performance measures for the major through movements are: volumeto- capacity ratio, Level of Service LOS, and the number of cycles to wait. The derived measures can be graphically visualized on Google Maps. The travel time data acquisition is performed using BlueTOAD devices. The goal is to introduce automated assessment tool, visualization and evaluation of the intersections’ performance measures simultaneously at multiple intersections. The main objective of this web application is to help traffic operators/engineers to evaluate performance of the signalized corridors exploiting the archived measured travel times.
Show less - Date Issued
- 2015
- PURL
- http://purl.flvc.org/fau/fd/FA00005907
- Format
- Document (PDF)
- Title
- Traffic Sign Effectiveness.
- Creator
- Kamholtz, Tali, Chozas, Ashley, Duitama, Luis, Knipp, Tammy, Office of Undergraduate Research and Inquiry
- Abstract/Description
-
Visual salience is the perception that renders some objects in the world to stand out from its given environment and immediately grab our attention. For the design of road signs, visual salience plays a significant role. Studies reveal poor salience of traffic signs contribute to the increase of traffic violations. With the aid of eye-tracking technology (analyzing visual fixations and saccadic patterns of licensed drivers), this paper will examine the visual salience and effectiveness for...
Show moreVisual salience is the perception that renders some objects in the world to stand out from its given environment and immediately grab our attention. For the design of road signs, visual salience plays a significant role. Studies reveal poor salience of traffic signs contribute to the increase of traffic violations. With the aid of eye-tracking technology (analyzing visual fixations and saccadic patterns of licensed drivers), this paper will examine the visual salience and effectiveness for the redesign of two specific road signs. We hypothesize remodeling the optical characteristics will improve visual attention for a given background and thus, reduce the number of traffic violations and ensure public safety.
Show less - Date Issued
- 2016
- PURL
- http://purl.flvc.org/fau/fd/FA00005564
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Trabecular Structure through Ontogeny in the Florida Manatee (Trichechus manatus latirostris).
- Creator
- Lindsey, Laura, Ingle, Danielle, Porter, Marianne
- Abstract/Description
-
Manatees, who use their vertebral column to propel themselves in swimming, are the product of a major evolutionary shift from land to water. This project explores the structure of trabecular (spongy) bone, which changes with force direction and magnitude, from the vertebral column of manatees. The goal of this research is to investigate the structural properties of manatee vertebral trabecular bone to better understand this animal's development and swimming mechanics. Vertebrae were dissected...
Show moreManatees, who use their vertebral column to propel themselves in swimming, are the product of a major evolutionary shift from land to water. This project explores the structure of trabecular (spongy) bone, which changes with force direction and magnitude, from the vertebral column of manatees. The goal of this research is to investigate the structural properties of manatee vertebral trabecular bone to better understand this animal's development and swimming mechanics. Vertebrae were dissected from four regions of the vertebral column and scanned with micro-computed tomography. Images were analyzed in BoneJ to quantify trabecular width, number, length, bone volume fraction (amount of bone/total area) and degree of anisotropy (orientation bias). Results from this project will be paired with mechanical data in future work to better understand forces on the vertebral column in a swimming mammal throughout development, and how these properties may have diverged from those found in their terrestrial counterparts.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000043
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- To Cleave or Not to Cleave? Defining the Functional Role of Amyloid Precursor Protein in the Development of the Drosophila Giant Fiber Circuit.
- Creator
- Richelle Poulos, Tyrone Penserga, Sirisha Kudumala, Tanja Godenschwege
- Date Issued
- 2017
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000018
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- TLR agonists differentially induce maturation of nicotine-exposed dendritic cell.
- Creator
- Tamjidi, Saba, Nourishirazi, Erika, Graduate College, Bible, Brittany, Zeng, Menghua, Nouri-Shirazi, Mahyar
- Abstract/Description
-
Background: Vaccines aid in saving lives from infections and biological warfare attacks. They should be effective in all target populations otherwise the likelihood that an unprotected person will transmit disease to a vulnerable individual is greatly increased. There is compelling evidence that smokers are less responsive to vaccination. We have reported that both therapeutic and prophylactic vaccines fail to protect and cure animals from disease due to negative effects of nicotine in...
Show moreBackground: Vaccines aid in saving lives from infections and biological warfare attacks. They should be effective in all target populations otherwise the likelihood that an unprotected person will transmit disease to a vulnerable individual is greatly increased. There is compelling evidence that smokers are less responsive to vaccination. We have reported that both therapeutic and prophylactic vaccines fail to protect and cure animals from disease due to negative effects of nicotine in biological activities of DCs. Using in vitro mouse culture system we have identified an appropriate TLR agonist capable of correcting the defects in DCs exposed to nicotine. Hypothesis: In order to translate these studies to human, we tested the hypothesis that appropriate TLR agonists will also correct the degrading effects of nicotine on human DCs and consequently DC-NK cross talk and T cell polarization. Methods: Monocyte-derived DCs were generated in culture media containing growth factors GM-CSF and IL-4 with or without nicotine treatment. DCs were activated with indicated TLR agonists and their phenotypes and cytokine profiles were analyzed by flow cytometry and ELISA, respectively. Results: Among the TLR agonists tested, we found that nicotine has less effect on human DC maturation in response to TLR4 plus TLR7/8 agonists as evidenced by expression levels of their costimulatory CD80/83/86/40 and antigen-presenting HLA-DR molecules as well as inflammatory cytokines IL-12, IL-10,TNF-α and IL-1β production. Conclusion: We are currently investigating whether these TLR agonists also augment human DC-NK bidirectional signals essential for T cell differentiation in a nicotinic environment.
Show less - Date Issued
- 2014
- PURL
- http://purl.flvc.org/fau/fd/FA00005169
- Format
- Document (PDF)
- Title
- Tissue-specific requirement of the autophagy gene atg-18 in controlling C. elegans dauer morphogenesis, fat metabolism and adult longevity.
- Creator
- Minnerly, Justin, Zhang, Jiuli, Graduate College, Jia, Kailiang
- Abstract/Description
-
The conserved insulin growth factor IGF signaling pathway is one of the major regulators of lifespan in many species including C. elegans. In C. elegans the insulin/IGF-like receptor is encoded by the daf-2 gene, mutations in which result in lifespan extension, fat accumulation and dauer formation. The daf-2 activity in the nervous system controls these phenotypes cell non-autonomously. Interestingly, the longevity phenotype of daf-2 mutant worms is dependent on macroautophagy hereafter...
Show moreThe conserved insulin growth factor IGF signaling pathway is one of the major regulators of lifespan in many species including C. elegans. In C. elegans the insulin/IGF-like receptor is encoded by the daf-2 gene, mutations in which result in lifespan extension, fat accumulation and dauer formation. The daf-2 activity in the nervous system controls these phenotypes cell non-autonomously. Interestingly, the longevity phenotype of daf-2 mutant worms is dependent on macroautophagy hereafter autophagy. Autophagy is a highly conserved lysosomal degradation pathway involved in the removal of long-lived proteins and cytoplasmic organelles. During autophagy, cellular components are sequestered into the double-membrane autophagosomes and delivered to lysosomes for degradation. Increasing evidence has emerged that the autophagy process is a central regulator of lifespan that is required for the effects of DAF-2 signaling, dietary restriction and some mitochondrial mutations on C. elegans longevity. It is unknown however whether autophagy activity in every tissue or in a single tissue mediates the influence of these longevity signals. To address this question, we examined the tissue requirement of autophagy gene atg-18 for the lifespan of wild type animals and the daf-2 mutant. We discovered that neurons and intestinal cells are two key tissues where atg-18 mediates the effect of DAF-2 insulin-like signaling on lifespan, fat accumulation and dauer morphogenesis, suggesting autophagy acts cell non-autonomously in controlling C. elegans dauer formation, fat metabolism and adult longevity.
Show less - Date Issued
- 2014
- PURL
- http://purl.flvc.org/fau/fd/FA00005160
- Format
- Document (PDF)
- Title
- THP-1 Monocyte Differentiation and Activation.
- Creator
- Blaise, Danice, Hartmann, James X.
- Abstract/Description
-
FAU's Office of Undergraduate Research and Inquiry hosts an annual symposium where students engaged in undergraduate research may present their findings either through a poster presentation or an oral presentation.
- Date Issued
- 2011
- PURL
- http://purl.flvc.org/fau/fd/FA00005429
- Format
- Document (PDF)
- Title
- The War on Neologisms in the Italian Language.
- Creator
- Baldocchi, Valeria, Ruthenberg, Myriam Swennen, Serra, Ilaria, Dorothy F. Schmidt College of Arts and Letters
- Abstract/Description
-
Globalization has become an agent of socioeconomic and communicative integration and today it envelops all aspects of human life. The quasi-immediate exchange of information that surpasses the now ancient barriers of time and space has triggered a sociocultural revolution with perceptible effects on the linguistic characteristics that are at the core of collective and individual identities. Among the most noticeable cultural changes are neologisms, which are often at the center of heated...
Show moreGlobalization has become an agent of socioeconomic and communicative integration and today it envelops all aspects of human life. The quasi-immediate exchange of information that surpasses the now ancient barriers of time and space has triggered a sociocultural revolution with perceptible effects on the linguistic characteristics that are at the core of collective and individual identities. Among the most noticeable cultural changes are neologisms, which are often at the center of heated linguistic debates. Some claim that the increased use of neologisms in the Italian language is a natural component of the fluctuating nature of a language and that their use enriches it. Linguistic purists take a more conservative stance and view neologisms as a linguistic enemy who blurs the distinctive differences among languages and robs them of their uniqueness. Neologisms are a mirror of contemporary Italian society and their use entails an often subconscious support of certain social currents.
Show less - Date Issued
- 2015
- PURL
- http://purl.flvc.org/fau/fd/FA00005175
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- The synergistic effects of concurrent stress on the inflammatory response in healthy individuals.
- Creator
- McAlpine, David, Huang, Chun-Jung
- Date Issued
- 2012-04-06
- PURL
- http://purl.flvc.org/fcla/dt/3349030
- Subject Headings
- Pentraxin 3, Inflammation, PTX3 protein, Vascular Diseases, Blood Vessels, C-Reactive Protein, Inflammation --blod, Parasympathetic Nervous System, Stress --psychological
- Format
- Document (PDF)
- Title
- The South Florida life sciences industry cluster: a regional innovation system (RIS) approach.
- Creator
- Vizcardo, Gonzalo, Oner, Asli Ceylan
- Date Issued
- 2013-04-05
- PURL
- http://purl.flvc.org/fcla/dt/3361223
- Subject Headings
- Industrial clusters, Knowledge economy, Florida
- Format
- Document (PDF)
- Title
- The Significance of Adult Day Care.
- Creator
- Waligora, Kyra, Tappen, Ruth M.
- Abstract/Description
-
The purpose of this research project is to investigate the impact adult day care centers have on cognitively impaired older adults and their caregivers. I extracted data from records of the Louis and Anne Green Memory and Wellness Center participants who have given consent and attended the center for a minimum of six months. I have discovered that participants benefit from this day center because they experience an improved quality of life, maintain a higher level of functioning, have more...
Show moreThe purpose of this research project is to investigate the impact adult day care centers have on cognitively impaired older adults and their caregivers. I extracted data from records of the Louis and Anne Green Memory and Wellness Center participants who have given consent and attended the center for a minimum of six months. I have discovered that participants benefit from this day center because they experience an improved quality of life, maintain a higher level of functioning, have more opportunities for socialization, and establish friendships and connections. Caregivers of participants enrolled in the day center also benefit because they receive access to caregiver support groups, are temporarily freed from the responsibility to care, and are pleased that participants attend the center and enjoy attending the center. These findings contribute to the current body of research literature that supports the contributions of adult day care centers.
Show less - Date Issued
- 2014
- PURL
- http://purl.flvc.org/fau/fd/FA0005040
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- The Role of the Nurse Navigator: Reducing 30-Day Readmissions?.
- Creator
- Leavitt, Mary Ann M., Graduate College
- Abstract/Description
-
The aim of this study is to compare readmission rates for patients who transition home from the hospital under the care of the Heart Failure Nurse Navigator (HFNN) with patients who receive usual home health care. Heart failure (HF) accounts for 20% of all hospital admissions and is the most common diagnosis associated with a 30-day readmission of Medicare patients. Nationally, 24.7% of patients with HF are readmitted within 30 days. The AHA and ACCF recognize a critical need for evidence...
Show moreThe aim of this study is to compare readmission rates for patients who transition home from the hospital under the care of the Heart Failure Nurse Navigator (HFNN) with patients who receive usual home health care. Heart failure (HF) accounts for 20% of all hospital admissions and is the most common diagnosis associated with a 30-day readmission of Medicare patients. Nationally, 24.7% of patients with HF are readmitted within 30 days. The AHA and ACCF recognize a critical need for evidence identifying best processes of care in transition from hospital to home. The comprehensive NN role not only teaches the patient to adapt to the prescribed medical protocol, but also provides connectedness and relationship. Home health nurses taught to perform the role of a HFNN may improve coordination of post-hospital care and patient outcomes. The research design will be sequential mixedmethod. Phase I will be a quantitative, quasi-experimental randomized study of the effect of HFNN on 30-day readmissions. Pre- and post-testing for HF self-care knowledge and quality-of-life will be analyzed by repeated ANOVA. Independent T-tests will compare readmission rates between groups. Phase II will be a qualitative study of transitioning home under the care of the HFNN. Intervention patients will be invited to focus groups, and their responses to semi-structured questions will be coded using conventional content analysis. It is hoped that the quantitative portion of the study will demonstrate that the HFNN intervention will keep more patients out of the hospital for at least 30 days and improve the HF self-care knowledge and quality of life. The qualitative portion may uncover unknown elements of the HFNN/patient dynamic, as well as themes helpful in formulating further questions about care of the patient with HF.
Show less - Date Issued
- 2015
- PURL
- http://purl.flvc.org/fau/fd/FA00005894
- Format
- Document (PDF)