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- Title
- A Collaborative Geospatial Shoreline Inventory Tool to Guide Coastal Development and Habitat Conservation.
- Creator
- Mitsova, Diana, Wissinger, Frank, Esnard, Ann-Margaret, Shankar, Ravi, Gies, Peter
- Date Issued
- 2013-05-13
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000175
- Format
- Citation
- Title
- A Critical Evaluation of the Nonparametric Approach to Estimate Terrestrial Evaporation.
- Creator
- Yang, Yongmin, Su, Hongbo, Qi, Jianwei
- Date Issued
- 2016
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000191
- Format
- Citation
- Title
- A Measurement Based Analysis of the Hydrokinetic Energy in the Gulf Stream.
- Creator
- Machado, Maria Carolina P. M., VanZwieten, James H.
- Date Issued
- 2015
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000361
- Format
- Citation
- Title
- A New Role for TIMP-1 in Modulating Neurite Outgrowth and Morphology of Cortical Neurons.
- Creator
- Ould-yahoui, Adlane, Tremblay, Evelyne, Sbai, Oualid, Ferhat, Lotfi, Bernard, Anne, Charrat, Eliane, Gueye, Yatma, Lim, Ngee Han, Brew, Keith, Risso, Jean-Jacques, Dive, Vincent, Khrestchatisky, Michel, Rivera, Santiago, Chédotal, Alain
- Date Issued
- 2009-12-14
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000096
- Format
- Citation
- Title
- A Remote Sensing Method for Estimating Surface Air Temperature and Surface Vapor Pressure on a Regional Scale.
- Creator
- Zhang, Renhua, Rong, Yuan, Tian, Jing, Su, Hongbo, Li, Zhao-Liang, Liu, Suhua
- Abstract/Description
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This paper presents a method of estimating regional distributions of surface air temperature (Ta) and surface vapor pressure (ea), which uses remotely-sensed data and meteorological data as its inputs. The method takes into account the effects of both local driving force and horizontal advection on Ta and ea. Good correlation coefficients (R2) and root mean square error (RMSE) between the measurements of Ta/ea at weather stations and Ta/ea estimates were obtained; with R^2 of 0.77, 0.82 and 0...
Show moreThis paper presents a method of estimating regional distributions of surface air temperature (Ta) and surface vapor pressure (ea), which uses remotely-sensed data and meteorological data as its inputs. The method takes into account the effects of both local driving force and horizontal advection on Ta and ea. Good correlation coefficients (R2) and root mean square error (RMSE) between the measurements of Ta/ea at weather stations and Ta/ea estimates were obtained; with R^2 of 0.77, 0.82 and 0.80 and RMSE of 0.42K, 0.35K and 0.20K for Ta and with R^2 of 0.85, 0.88, 0.88 and RMSE of 0.24hpa, 0.35hpa and 0.16hpa for ea, respectively, for the three-day results. This result is much better than that estimated from the inverse distance weighted method (IDW). The performance of Ta/ea estimates at Dongping Lake illustrated that the method proposed in the paper also has good accuracy for a heterogeneous surface. The absolute biases of Ta and ea estimates at Dongping Lake from the proposed method are less than 0.5Kand 0.7hpa, respectively, while the absolute biases of them from the IDW method are more than 2K and 3hpa, respectively. Sensitivity analysis suggests that the Ta estimation method presented in the paper is most sensitive to surface temperature and that the ea estimation method is most sensitive to available energy.
Show less - Date Issued
- 2015-05-13
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000053
- Format
- Citation
- Title
- A survey of compliance issues in cloud computing.
- Creator
- Yimam, Dereje, Fernandez, Eduardo B.
- Date Issued
- 2016-12-10
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000139
- Format
- Citation
- Title
- A Well-Kept Treasure at Depth: Precious Red Coral Rediscovered in Atlantic Deep Coral Gardens (SW Portugal) after 300 Years.
- Creator
- Boavida, Joana, Paulo, Diogo, Aurelle, Didier, Arnaud-Haond, Sophie, Marschal, Christian, Reed, John K., Gonçalves, Jorge M. S., Serrao, Ester A., Pronzato, Roberto
- Abstract/Description
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Background The highly valuable red coral Corallium rubrum is listed in several Mediterranean Conventions for species protection and management since the 1980s. Yet, the lack of data about its Atlantic distribution has hindered its protection there. This culminated in the recent discovery of poaching activities harvesting tens of kg of coral per day from deep rocky reefs off SW Portugal. Red coral was irregularly exploited in Portugal between the 1200s and 1700s, until the fishery collapsed....
Show moreBackground The highly valuable red coral Corallium rubrum is listed in several Mediterranean Conventions for species protection and management since the 1980s. Yet, the lack of data about its Atlantic distribution has hindered its protection there. This culminated in the recent discovery of poaching activities harvesting tens of kg of coral per day from deep rocky reefs off SW Portugal. Red coral was irregularly exploited in Portugal between the 1200s and 1700s, until the fishery collapsed. Its occurrence has not been reported for the last 300 years. Results Here we provide the first description of an Atlantic red coral assemblage, recently rediscovered dwelling at 60–100 m depth in southern Portugal.We report a very slow growth rate (0.23 mm year-1), comparable to Mediterranean specimens. In comparison with most of the Mediterranean reports, the population reaches much larger sizes, estimated to be over one century old, and has a more complex coral branch architecture that promotes a rich assemblage of associated species, with boreal and Mediterranean affinities. Atlantic red coral is genetically distinct, yet mitochondrial analyses suggest that red corals from the Atlantic may have introgressed the Mediterranean ones after migration via the Algeria current. Our underwater surveys, using advanced mixed-gas diving, retrieved lost fishing gear in all coral sites. Besides illegal harvesting, the use and loss of fishing gears, particularly nets, by local fisheries are likely sources of direct impacts on these benthic assemblages. Conclusions We extended the knowledge on the distribution of C. rubrum in the Atlantic, discovered its genetic distinctiveness, and reveal a rich deep-dwelling fauna associated to these coral assemblages. These findings support a barrier role of the Atlantic-Mediterranean transition zone, but reveal also hints of connectivity along its southern margin. The results highlight the genetic and demographic uniqueness of red coral populations from SW Iberia. However, we also report threats to these vulnerable populations by direct and indirect fishing activities and argue that its protection from any mechanically destructive activities is urgent as a precautionary approach. This study advances our understanding of phylogeographic barriers and range edge genetic diversity, and serves as a baseline against which to monitor future human and environmental disturbances to Atlantic C. rubrum.
Show less - Date Issued
- 2016-01-22
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000048
- Format
- Citation
- Title
- Aberrant Autolysosomal Regulation Is Linked to The Induction of Embryonic Senescence: Differential Roles of Beclin 1 and p53 in Vertebrate Spns1 Deficiency.
- Creator
- Sasaki, Tomoyuki, Lian, Shanshan, Qi, Jie, Bayliss, Peter E., Carr, Christopher E., Johnson, Jennifer L., Guha, Sujay, Kobler, Patrick, Catz, Sergio D., Gill, Matthew S., Jia, Kailiang, Klionsky, Daniel J., Kishi, Shuji, Mullins, Mary C.
- Abstract/Description
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Spinster (Spin) in Drosophila or Spinster homolog 1 (Spns1) in vertebrates is a putative lysosomal H+-carbohydrate transporter, which functions at a late stage of autophagy. The Spin/Spns1 defect induces aberrant autolysosome formation that leads to embryonic senescence and accelerated aging symptoms, but little is known about the mechanisms leading to the pathogenesis in vivo. Beclin 1 and p53 are two pivotal tumor suppressors that are critically involved in the autophagic process and its...
Show moreSpinster (Spin) in Drosophila or Spinster homolog 1 (Spns1) in vertebrates is a putative lysosomal H+-carbohydrate transporter, which functions at a late stage of autophagy. The Spin/Spns1 defect induces aberrant autolysosome formation that leads to embryonic senescence and accelerated aging symptoms, but little is known about the mechanisms leading to the pathogenesis in vivo. Beclin 1 and p53 are two pivotal tumor suppressors that are critically involved in the autophagic process and its regulation. Using zebrafish as a genetic model, we show that Beclin 1 suppression ameliorates Spns1 lossmediated senescence as well as autophagic impairment, whereas unexpectedly p53 deficit exacerbates both of these characteristics. We demonstrate that 'basal p53' activity plays a certain protective role(s) against the Spns1 defect-induced senescence via suppressing autophagy, lysosomal biogenesis, and subsequent autolysosomal formation and maturation, and that p53 loss can counteract the effect of Beclin 1 suppression to rescue the Spns1 defect. By contrast, in response to DNA damage, 'activated p53' showed an apparent enhancement of the Spns1-deficient phenotype, by inducing both autophagy and apoptosis. Moreover, we found that a chemical and genetic blockage of lysosomal acidification and biogenesis mediated by the vacuolar-type H+-ATPase, as well as of subsequent autophagosome-lysosome fusion, prevents the appearance of the hallmarks caused by the Spns1 deficiency, irrespective of the basal p53 state. Thus, these results provide evidence that Spns1 operates during autophagy and senescence differentially with Beclin 1 and p53.
Show less - Date Issued
- 2014-06-26
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000072
- Format
- Citation
- Title
- Abundance of megalin and Dab2 is reduced in syncytiotrophoblast during placental malaria, which may contribute to low birth weight.
- Creator
- Lybbert, Jared, Gullingsrud, Justin, Chesnokova, Olga, Turyakira, Eleanor, Dhorda, Mehul, Guerin, Philippe J., Piola, Patrice, Muehlenbachs, Atis, Oleinikov, Andrew V.
- Date Issued
- 2016-07-13
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000107
- Format
- Citation
- Title
- Action Research in Schools and Communities.
- Creator
- Vaughan, Michelle, Wolfe, Kathryn
- Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000363
- Format
- Citation
- Title
- Acute Alcohol Drinking Promotes Piecemeal Percepts during Binocular Rivalry.
- Creator
- Cao, Dingcai, Zhuang, Xiaohua, Kang, Para, Hong, Sang Wook, King, Andrea C.
- Date Issued
- 2016-04-06
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000148
- Format
- Citation
- Title
- An Attention-Driven Model for Grouping Similar Images with Image Retrieval Applications.
- Creator
- Marques, Oge, Mayron, Liam M, Borba, Gustavo B, Gamba, Humberto R
- Date Issued
- 2007
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000171
- Format
- Citation
- Title
- An Exploration of Indexed and Non-Indexed Open Access Journals: Identifying Metadata Coding Variations.
- Creator
- Allen, Ethan J., Weber, Roberta K.
- Date Issued
- 2015-07-03
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000116
- Format
- Citation
- Title
- An Introduction to Evolutionary Developmental Psychology.
- Creator
- Machluf, Karin, Liddle, James R., Bjorklund, David F.
- Date Issued
- 2014-04
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000122
- Format
- Citation
- Title
- Analysis of the Urban Heat Island Effect in Shijiazhuang, China Using Satellite and Airborne Data.
- Creator
- Liu, Kai, Su, Hongbo, Zhang, Lifu, Yang, Hang, Zhang, Renhua, Li, Xueke
- Abstract/Description
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The urban heat island (UHI) effect resulting from rapid urbanization generally has a negative impact on urban residents. Shijiazhuang, the capital of Hebei Province in China, was selected to assess surface thermal patterns and its correlation with Land Cover Types (LCTs). This study was conducted using Landsat TM images on the mesoscale level and airborne hyperspectral thermal images on the microscale level. Land surface temperature (LST) was retrieved from four scenes of Landsat TM data in...
Show moreThe urban heat island (UHI) effect resulting from rapid urbanization generally has a negative impact on urban residents. Shijiazhuang, the capital of Hebei Province in China, was selected to assess surface thermal patterns and its correlation with Land Cover Types (LCTs). This study was conducted using Landsat TM images on the mesoscale level and airborne hyperspectral thermal images on the microscale level. Land surface temperature (LST) was retrieved from four scenes of Landsat TM data in the summer days to analyze the thermal spatial patterns and intensity of surface UHI (SUHI). Surface thermal characteristics were further examined by relating LST to percentage of imperious surface area (ISA%) and four remote sensing indices (RSIs), the Normalized Difference Vegetation Index (NDVI), Universal Pattern Decomposition method (VIUPD), Normalized Difference Built-up Index (NDBI) and Biophysical Composition Index (BCI). On the other hand, fives scenes of airborne TASI (Thermal Airborne Spectrographic Imager sensor) images were utilized to describe more detailed urban thermal characteristics of the downtown of Shijiazhuang city. Our results show that an obvious surface heat island effect existed in the study area during summer days, with a SUHI intensity of 2–4 °C. The analyses reveal that ISA% can provide an additional metric for the study of SUHI, yet its association with LST is not straightforward and this should a focus in future work. It was also found that two physically based indices, VIUPD and BCI, have the potential to account for the variation in urban LST. The results concerning on TASI indicate that diversity of impervious surfaces (rooftops, concrete, and mixed asphalt) contribute most to the SUHI, among all of the land cover features. Moreover, the effect of impervious surfaces on LST is complicated, and the composition and arrangement of land cover features may play an important role in determining the magnitude and intensity of SUHI. Overall, the analysis of urban thermal signatures at two spatial scales complement each other and the use of airborne imagery data with higher spatial resolution is helpful in revealing more details for understanding urban thermal environments.
Show less - Date Issued
- 2015-04-20
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000054
- Format
- Citation
- Title
- Anti-malarial effect of semi-synthetic drug amitozyn.
- Creator
- Tcherniuk, Sergey O., Chesnokova, Olga, Oleinikov, Irina V., Potopalsky, Anatoly I., Oleinikov, Andrew V.
- Date Issued
- 2015-12-29
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000176
- Format
- Citation
- Title
- Antibodies elicited by the first non-viral prophylactic cancer vaccine show tumor-specificity and immunotherapeutic potential.
- Creator
- Lohmueller, Jason J., Sato, Shuji, Popova, Lana, Chu, Isabel M., Tucker, Meghan A., Barberena, Roberto, Innocenti, Gregory M., Cudic, Mare, Ham, James D., Cheung, Wan Cheung, Polakiewicz, Roberto D., Finn, Olivera J.
- Abstract/Description
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MUC1 is a shared tumor antigen expressed on >80% of human cancers. We completed the first prophylactic cancer vaccine clinical trial based on a non-viral antigen, MUC1, in healthy individuals at-risk for colon cancer. This trial provided a unique source of potentially effective and safe immunotherapeutic drugs, fully-human antibodies affinity-matured in a healthy host to a tumor antigen. We purified, cloned, and characterized 13 IgGs specific for several tumor-associated MUC1 epitopes with a...
Show moreMUC1 is a shared tumor antigen expressed on >80% of human cancers. We completed the first prophylactic cancer vaccine clinical trial based on a non-viral antigen, MUC1, in healthy individuals at-risk for colon cancer. This trial provided a unique source of potentially effective and safe immunotherapeutic drugs, fully-human antibodies affinity-matured in a healthy host to a tumor antigen. We purified, cloned, and characterized 13 IgGs specific for several tumor-associated MUC1 epitopes with a wide range of binding affinities. These antibodies bind hypoglycosylated MUC1 on human cancer cell lines and tumor tissues but show no reactivity against fully-glycosylated MUC1 on normal cells and tissues. We found that several antibodies activate complement-mediated cytotoxicity and that T cells carrying chimeric antigen receptors with the antibody variable regions kill MUC1+ target cells, express activation markers, and produce interferon gamma. Fully-human and tumor-specific, these antibodies are candidates for further testing and development as immunotherapeutic drugs.
Show less - Date Issued
- 2016-10-22
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000012
- Format
- Citation
- Title
- Antioptimization of earthquake exitation and response.
- Creator
- Zuccaro, G., Elishakoff, Isaac, Baratta, A.
- Abstract/Description
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The paper presents a novel approach to predict the response of earthquake-excited structures. The earthquake excitation is expanded in terms of series of deterministic functions. The coefficients of the series are represented as a point in N-dimensional space. Each available accelerogram at a certain site is then represented as a point in the above space, modeling the available fragmentary historical data. The minimum volume ellipsoid, containing all points, is constructed. The ellipsoidal...
Show moreThe paper presents a novel approach to predict the response of earthquake-excited structures. The earthquake excitation is expanded in terms of series of deterministic functions. The coefficients of the series are represented as a point in N-dimensional space. Each available accelerogram at a certain site is then represented as a point in the above space, modeling the available fragmentary historical data. The minimum volume ellipsoid, containing all points, is constructed. The ellipsoidal models of uncertainty, pertinent to earthquake excitation, are developed. The maximum response of a structure, subjected to the earthquake excitation, within ellipsoidal modeling of the latter, is determined. This procedure of determining least favorable response was termed in the literature (Elishakoff, 1991) as an antioptimization. It appears that under inherent uncertainty of earthquake excitation, antioptimization analysis is a viable alternative to stochastic approach.
Show less - Date Issued
- 1998
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000014
- Format
- Citation
- Title
- Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers.
- Creator
- Roner, Michael R., Carraher, Charles E., Shahi, Kimberly, Barot, Girish
- Abstract/Description
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Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth. As most DNA and some RNA viruses require, and even induce, infected cells to initiate DNA replication and subsequent cell division, compounds with antitumor activity will...
Show morePolymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth. As most DNA and some RNA viruses require, and even induce, infected cells to initiate DNA replication and subsequent cell division, compounds with antitumor activity will very likely also possess antiviral activity. This article examines the use of metal-containing polymers as a novel class of antivirals.
Show less - Date Issued
- 2011-05-27
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000008
- Format
- Citation
- Title
- Antonio Ruiz de Montoya, Apostle of the Guaraní.
- Creator
- Ganson, Barbara
- Abstract/Description
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This essay highlights the accomplishments of one of the foremost Jesuit missionaries in seventeenth-century Paraguay, Antonio Ruiz de Montoya. Born in Lima, Montoya distinguished himself as a chronicler of the first encounters between the Jesuits and the Guaraní Indians of South America. He defended Indian rights by speaking out against Indian slavery. Montoya spent approximately twenty-five years among the Guaraní indigenous peoples who influenced his worldview and sense of spirituality,...
Show moreThis essay highlights the accomplishments of one of the foremost Jesuit missionaries in seventeenth-century Paraguay, Antonio Ruiz de Montoya. Born in Lima, Montoya distinguished himself as a chronicler of the first encounters between the Jesuits and the Guaraní Indians of South America. He defended Indian rights by speaking out against Indian slavery. Montoya spent approximately twenty-five years among the Guaraní indigenous peoples who influenced his worldview and sense of spirituality, which are reflected in his 1636 first account of the Jesuit reducciones in Paraguay, Conquista espiritual hecha por los religiosos de la Compañía de Jesús en las provincias del Paraguay, Paraná, Uruguay, y Tapé.
Show less - Date Issued
- 2016-03-01
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000019
- Format
- Citation