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Title
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Chemotaxonomy of the marine sponge Xestospongia muta.
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Creator
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Reddy, Manoj Kumar., Florida Atlantic University, Kerr, Russell G.
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Abstract/Description
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Chemical analysis of large number of specimens of the sponge Xestospongia muta have revealed the existence of three distinct sterol chemotypes. Since sponges are well known to contain a diverse array of all classes of lipids, the utility of fatty acid composition as a chemotaxonomic tool for Xestospongia muta has been addressed. Further the biosynthetic capabilities of the three chemotypes are being evaluated for possible taxonomic use. Further the utility of TLC and NMR as additional...
Show moreChemical analysis of large number of specimens of the sponge Xestospongia muta have revealed the existence of three distinct sterol chemotypes. Since sponges are well known to contain a diverse array of all classes of lipids, the utility of fatty acid composition as a chemotaxonomic tool for Xestospongia muta has been addressed. Further the biosynthetic capabilities of the three chemotypes are being evaluated for possible taxonomic use. Further the utility of TLC and NMR as additional taxonomic tools has also been evaluated.
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Date Issued
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1995
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PURL
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http://purl.flvc.org/fcla/dt/15167
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Subject Headings
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Chemotaxonomy, Sponges, Sterols
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Format
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Document (PDF)
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Title
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In vitro biosynthetic studies of stevensine, a natural product from the sponge Teichaxinella morchella.
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Creator
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Andrade, Paul., Florida Atlantic University, Kerr, Russell G.
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Abstract/Description
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Stevensine is a biologically active secondary metabolite produced by several marine sponges, including Teichaxinella morchella. Two in vitro methods were used to investigate the biosynthetic origin of stevensine in the sponge T. morchella. A cell-free enzyme extract was developed to test for the incorporation of the potential radiolabeled metabolic precursors histidine, arginine, ornithine, and proline. Secondly, cell cultures of T. morchella were used to determine the biosynthetic origin of...
Show moreStevensine is a biologically active secondary metabolite produced by several marine sponges, including Teichaxinella morchella. Two in vitro methods were used to investigate the biosynthetic origin of stevensine in the sponge T. morchella. A cell-free enzyme extract was developed to test for the incorporation of the potential radiolabeled metabolic precursors histidine, arginine, ornithine, and proline. Secondly, cell cultures of T. morchella were used to determine the biosynthetic origin of stevensine from the radiolabeled amino acids histidine, arginine, ornithine, and proline. Histidine and ornithine/proline were converted to stevensine in the cell culture system. This represents the first study involving the use of cell cultures of a marine invertebrate to investigate the biosynthesis of a biologically active natural product. An understanding of the biosynthetic process leading to the production of this compound in the source organism could lead to the development of more efficient and environmentally safer production methods.
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Date Issued
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1999
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PURL
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http://purl.flvc.org/fcla/dt/15620
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Subject Headings
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Sponges, Marine biotechnology, Marine pharmacology
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Format
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Document (PDF)
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Title
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Novel compounds isolated from the marine sponge Clathria sp.
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Creator
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Rueda de Leon, Rolando, Gupta, Prasoon, West, Lyndon, Graduate College
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Date Issued
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2011-04-08
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PURL
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http://purl.flvc.org/fcla/dt/3164772
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Subject Headings
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Sponges, Stereochemistry, Marine pharmacology
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Format
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Document (PDF)
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Title
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Collections of marine organisms for research on natural products chemistry and biodiversity: A survey of the benthic communities with emphasis on porifera, octocorals, and algae from the reefs and grassbeds of Bootless Bay, Papua New Guinea.
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Creator
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Reed, John K., Kelly-Borges, M., Janda, Kathleen E., Reed, Sherry A.
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Date Issued
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1997-03-25
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PURL
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http://purl.flvc.org/fcla/dt/3359854
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Subject Headings
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Biomedical research, Biodiversity--Research, New Guinea, Octocorallia, Porifera, Sponges, Algae, Marine natural products
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Format
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Document (PDF)
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Title
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Comparison of bacterial diversity within the coral reef sponge, Axinella corrugata, the encrusting coral Erythropodium caribaeorum.
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Creator
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Lopez, Jose V., Ranzer, L. K., Ledger, Angela, Schoch, B., Duckworth, Alan R., McCarthy, Peter J., Kerr, Russell G.
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Date Issued
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2008
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PURL
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http://purl.flvc.org/fau/fd/FA00007036
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Subject Headings
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Sponges, Corals, Heterotrophic bacteria, Symbiosis, RNA, Ribosomal, 16S
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Format
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Document (PDF)
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Title
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The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells.
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Creator
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Kowalski, R. J., Giannakakou, P., Gunasekera, Sarath P., Longley, Ross E., Day, B. W., Hamel, E., Harbor Branch Oceanographic Institute
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Date Issued
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1997
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PURL
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http://purl.flvc.org/fau/fd/FA00007052
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Subject Headings
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Marine natural products, Cytotoxins, Tubulin Modulators, Paclitaxel, Lactones, Sponges
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Format
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Document (PDF)
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Title
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Stereochemical determination of dictyostatin, a novel microtubule-stabilising macrolide from the marine sponge Corallistidae sp.
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Creator
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Paterson, Ian, Britton, R., Delgado, Oscar, Wright, Amy E.
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Date Issued
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2004
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PURL
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http://purl.flvc.org/fau/fd/FA00007061
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Subject Headings
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Macrolides, Sponges, Tubulin Modulators, Stereochemistry, Microtubules, Polyketides, Antimitotic Agents
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Format
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Document (PDF)
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Title
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Total synthesis of a potent hybrid of the anticancer natural products dictyostatin and discodermolide.
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Creator
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Paterson, Ian, Naylor, G. J., Wright, Amy E.
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Date Issued
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2008
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PURL
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http://purl.flvc.org/fau/fd/FA00007062
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Subject Headings
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Antineoplastic agents, Macrolides, Polyketides, Tubulin Modulators, Marine natural products, Sponges
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Format
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Document (PDF)
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Title
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Early effects of Lasonolide A on pancreatic cancer cells.
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Creator
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Isbrucker, Richard A., Guzman, Esther A., Pitts, Tara P., Wright, Amy E.
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Date Issued
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2000
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PURL
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http://purl.flvc.org/fau/fd/FA00007053
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Subject Headings
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Macrolides, Sponges, Marine natural products, Pancreatic Neoplasms, Pancreas--Cancer
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Format
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Document (PDF)
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Title
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Tsukamurella spongiae sp. nov., a novel actinomycete isolated from a deep-water marinesponge.
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Creator
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Olson, Julie B., Harmody, Dedra K., Bej, A. K., McCarthy, Peter J.
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Date Issued
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2007
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PURL
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http://purl.flvc.org/fau/fd/FA00007117
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Subject Headings
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Curaçao, Sponges, Actinobacteria, Actinomycetes, RNA, Ribosomal, 16S
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Format
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Document (PDF)
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Title
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1,1-Dimethyl-5,6-dihydroxyindolinium chloride from a deep water marine sponge, Dercitus sp.
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Creator
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Kohmoto, S., McConnell, O. J., Wright, Amy E.
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Date Issued
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1988
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PURL
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http://purl.flvc.org/fau/fd/FA00007184
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Subject Headings
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Sponges, Marine metabolites, Chemical structure
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Format
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Document (PDF)
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Title
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Antitumor activity and nucleic acid binding properties of Dercitin, a new acridinealkaloid isolated from a marine dercitus species sponge.
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Creator
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Burres, N. S., Sazesh, S., Gunawardana, G. P., Clement, J. J., Harbor Branch Oceanographic Institute
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Date Issued
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1989
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PURL
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http://purl.flvc.org/fau/fd/FA00007199
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Subject Headings
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Alkaloids, Acridines, Sponges, Antineoplastic agents, Cytotoxins, Marine natural products
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Format
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Document (PDF)
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Title
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Description of a new lithistid spongefrom northeastern New Zealand, and consideration of the phylogenetic affinities of familiesCorallistidae and Neopeltidae.
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Creator
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Kelly-Borges, M., Harbor Branch Oceanographic Institute
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Date Issued
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2000
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PURL
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http://purl.flvc.org/fau/fd/FA00007208
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Subject Headings
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New Zealand, Sponges, Demospongiae, Phylogeny, Sponges--Classification
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Format
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Document (PDF)
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Title
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Isometachromin, a new cytotoxic sesquiterpenoid from a deep water sponge of the family Spongiidae.
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Creator
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McConnell, O. J., Longley, Ross E., Gunasekera, M., Harbor Branch Oceanographic Institute
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Date Issued
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1992
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PURL
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http://purl.flvc.org/fau/fd/FA00007220
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Subject Headings
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Sponges, Sesquiterpenes, Cytotoxins, Porifera
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Format
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Document (PDF)
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Title
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Spongionella foliascens: a new foliose dendroceratid sponge from the western Atlantic.
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Creator
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Kelly-Borges, M., Pomponi, Shirley A., Vacelet, J.
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Date Issued
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1993
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PURL
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http://purl.flvc.org/fau/fd/FA00007223
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Subject Headings
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Mexico, Gulf of, Porifera, Sponges, Taxonomy, Animal, Species
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Format
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Document (PDF)
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Title
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Stochastic events and dynamics of a mangrove root epifaunal community.
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Creator
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Bingham, Brian L., Young, Craig M., Harbor Branch Oceanographic Institute
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Date Issued
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1995
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PURL
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http://purl.flvc.org/fau/fd/FA00007233
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Subject Headings
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Mangroves, Ascidians, Sponges, Stability
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Format
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Document (PDF)
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Title
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A new species of poecilosclerid sponge (Porifera) from bathyal methane seeps in the Gulf ofMexico.
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Creator
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Maldonado, Manuel, Young, Craig M., Harbor Branch Oceanographic Institute
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Date Issued
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1998
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PURL
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http://purl.flvc.org/fau/fd/FA00007236
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Subject Headings
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Mexico, Gulf of, Sponges, Porifera, Poecilosclerida, Methane, Species
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Format
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Document (PDF)
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Title
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Limits on the bathymetric distribution ofkeratose sponges: a field test in deep water.
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Creator
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Maldonado, Manuel, Young, Craig M., Harbor Branch Oceanographic Institute
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Date Issued
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1998
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PURL
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http://purl.flvc.org/fau/fd/FA00007237
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Subject Headings
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Sponges, Sponges--Ecology, Symbiosis, Demospongiae
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Format
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Document (PDF)
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Title
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Eryloside E from an Atlantic sponge Erylus goffrilleri.
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Creator
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Gulavita, N. K., Wright, Amy E., Kelly-Borges, M., Longley, Ross E., Yarwood, Donna, Sills, Matthew A.
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Date Issued
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1994
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PURL
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http://purl.flvc.org/fau/fd/FA00007261
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Subject Headings
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Sponges, Terpenes, Glycosides, Chemical structure
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Format
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Document (PDF)
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Title
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Characterization of an interleukin 6 cytokinefamily antagonist protein from a marine sponge, Callyspongia sp.
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Creator
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Peppard, J. V., Loo, P., Sills, Matthew A., Munster, D., Pomponi, Shirley A., Wright, Amy E.
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Date Issued
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1996
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PURL
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http://purl.flvc.org/fau/fd/FA00007266
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Subject Headings
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Sponges, Interleukin-6, Cytokines--antagonists & inhibitors
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Format
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Document (PDF)
Pages