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- Title
- 2D:4D FINGER RATIO IN CROSSFIT ATHLETES.
- Creator
- Wang, Calren, Wetterer, James, Florida Atlantic University, Harriet L. Wilkes Honors College
- Abstract/Description
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The second digit and fourth digit (2D:4D) finger ratio is known to be an indicator of in utero androgen influence. Here, I review current research concerning 2D:4D ratio, particularly in regards to muscle strength, muscle mass, and athletic ability. Studies on athletes have shown a significant negative correlation between the ratio and athleticism and an inconsistent correlation with muscle mass and muscle strength. I propose a research study on the relationship between the 2D:4D ratio and...
Show moreThe second digit and fourth digit (2D:4D) finger ratio is known to be an indicator of in utero androgen influence. Here, I review current research concerning 2D:4D ratio, particularly in regards to muscle strength, muscle mass, and athletic ability. Studies on athletes have shown a significant negative correlation between the ratio and athleticism and an inconsistent correlation with muscle mass and muscle strength. I propose a research study on the relationship between the 2D:4D ratio and Crossfit athletes and its relationship to muscle mass and muscle strength.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00060
- Format
- Document (PDF)
- Title
- Alarm pheromones in aquatic snail species: schreckstoff and stuff.
- Creator
- Apap, Ian, Wetterer, James, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
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Many aquatic organisms show alarm responses to chemical cues. For my thesis research, I tested whether two species of aquatic snail (one freshwater and one estuarine) show response to chemicals released by a crushed conspecific. I measured behavioral reaction of a freshwater snail and an estuarine snail species. I first tested the species from a freshwater pond, comparing the behavior of snail exposed to crushed snail extract with controls over a period of 24 h. In the first trial,...
Show moreMany aquatic organisms show alarm responses to chemical cues. For my thesis research, I tested whether two species of aquatic snail (one freshwater and one estuarine) show response to chemicals released by a crushed conspecific. I measured behavioral reaction of a freshwater snail and an estuarine snail species. I first tested the species from a freshwater pond, comparing the behavior of snail exposed to crushed snail extract with controls over a period of 24 h. In the first trial, significantly more snails climbed out of the water at the 8-h mark (χ2=8.86, p<.05) and the 24-h mark (χ2=4.98, p<.05). In the second trial, this difference was significant at the 2-h mark (χ2=4.43, p<.05). In one trial with estuarine snails, I found no evidence of an alarm response. The differences in response between the two species may relate to differences in environment. Alarm chemicals may supply useful information on local predation in a pond with little water movement, but not in an estuary, where water flow would quickly disperse these chemicals.
Show less - Date Issued
- 2011
- PURL
- http://purl.flvc.org/fau/fd/FA00003555
- Format
- Document (PDF)
- Title
- ALTRUISTIC BEHAVIOR AMOUNG CAPTIVE CHIMPANZEES.
- Creator
- Ranaweera, Esha, Wetterer, James, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
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Altruism plays an essential role in maintaining cooperative societies. From September 2021 to January 2022, I studied a group of seven chimpanzees (two males and five females) living in Lion Country Safari, recording acts of altruism related to grooming, food and water sharing, and border patrol. I found males on average both gave and received more grooming sessions. Among the few food and water sharing events I observed, males-males sharing was the most common. The two males performed almost...
Show moreAltruism plays an essential role in maintaining cooperative societies. From September 2021 to January 2022, I studied a group of seven chimpanzees (two males and five females) living in Lion Country Safari, recording acts of altruism related to grooming, food and water sharing, and border patrol. I found males on average both gave and received more grooming sessions. Among the few food and water sharing events I observed, males-males sharing was the most common. The two males performed almost all the border patrol. Altruistic behaviors among chimpanzees help bind their social groups in ways analogous to the human behaviors.
Show less - Date Issued
- 2022
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00213
- Format
- Document (PDF)
- Title
- Analysis of Mutant Manganese-Superoxide Dismutase on the Lifespan of Saccharomyces cerevisiae"".
- Creator
- Salem, Sarah, Kirchman, Paul A., Wetterer, James, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
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Previously isolated mutants of the superoxide dismutase 2 gene (SOD2), selected for increased activity in E. coli, were transformed into yeast cells in order to observe their effects on aging. Polymerase chain reaction and DNA sequencing were used to confirm that the yeast incorporated the mutant form of the gene. The strains with mutant forms of the SOD2 gene were observed to have decreased growth rates compared to the unmutated strain. Lifespan analyses were then conducted in order to see...
Show morePreviously isolated mutants of the superoxide dismutase 2 gene (SOD2), selected for increased activity in E. coli, were transformed into yeast cells in order to observe their effects on aging. Polymerase chain reaction and DNA sequencing were used to confirm that the yeast incorporated the mutant form of the gene. The strains with mutant forms of the SOD2 gene were observed to have decreased growth rates compared to the unmutated strain. Lifespan analyses were then conducted in order to see if yeast with mutant versions of SOD2 had lifespans that differed significantly from those with the unmutated forms of the gene. The mutant forms of SOD2 had no significant effect on the lifespan of yeast.
Show less - Date Issued
- 2011
- PURL
- http://purl.flvc.org/fau/fd/FA00003604
- Format
- Document (PDF)
- Title
- Assaying Mutant Marine Bacteria for Lithium Extraction.
- Creator
- Alexander, Didier, Kirchman, Paul A., Wetterer, James, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
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Lithium (Li) is used in many commercial products. With the recent development of a potent new lithium battery suitable for hybrid and plug-in electric cars, demand for lithium should soar. Seawater has low Li ion concentrations, and has not been considered a profitable commercial source of this element. For my thesis work, I attempted to develop a mutant strain of the marine bacteria Photobacterium damselae subsp. damselae capable of sequestering lithium from seawater. I expose the bacteria...
Show moreLithium (Li) is used in many commercial products. With the recent development of a potent new lithium battery suitable for hybrid and plug-in electric cars, demand for lithium should soar. Seawater has low Li ion concentrations, and has not been considered a profitable commercial source of this element. For my thesis work, I attempted to develop a mutant strain of the marine bacteria Photobacterium damselae subsp. damselae capable of sequestering lithium from seawater. I expose the bacteria to shortwave ultra violet (UV) light with the intent of obtaining a lithium dependent mutant. I was not successful at isolating such a mutant. However, I noted differences in colony size, between colonies grown in lithium media and sodium media, after UV treatment. Based on other research, the bacterial recovery methods of lithium and other metals from seawater remains a plausible option.
Show less - Date Issued
- 2011
- PURL
- http://purl.flvc.org/fau/fd/FA00003553
- Format
- Document (PDF)
- Title
- Balancing speed and safety as the rush to find effective and prolonged treatments for COVID-19 continue.
- Creator
- Garcia, Alberto, Wetterer, James, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
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The ongoing COVID-19 pandemic has severely impacted life around the world. As of early December 2020, more than 69 million people have tested positive for the virus, and more than 1.6 million people have died from the disease. Researchers are now rushing to find effective means of treating and preventing this disease. The urgency of this problem requires speed, but this must be balanced with caution to avoid possible negative impacts of deploying treatments that have been insufficiently...
Show moreThe ongoing COVID-19 pandemic has severely impacted life around the world. As of early December 2020, more than 69 million people have tested positive for the virus, and more than 1.6 million people have died from the disease. Researchers are now rushing to find effective means of treating and preventing this disease. The urgency of this problem requires speed, but this must be balanced with caution to avoid possible negative impacts of deploying treatments that have been insufficiently tested for effectiveness and safety. For my thesis, I consider challenges of the US Federal Drug Administration (FDA) to balance the urgency of finding quick treatment with the long-term safety of the treatments they approve. I first examine three historical examples where past treatments have been prematurely approved and discuss the lessons that were learned from these mistakes. Finally, I examine two examples from the current COVID-19 pandemic: the emergency use authorization to use hydroxychloroquine to treat severe COVID-19 patients and the new vaccines developed to prevent COVID-19 infection. It is pertinent to ensure that the benefits of any treatment outweigh the risks for the long-term benefit of society, which is of critical importance today as we face the current COVID-19 pandemic.
Show less - Date Issued
- 2021
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00140
- Format
- Document (PDF)
- Title
- CAN BRAIN NATRIURETIC PEPTIDE BE A PROGNOSTIC INDICATOR FOR CONGESTIVE HEART FAILURE PATIENTS NEARING DEATH?.
- Creator
- Pisarra, Cory, Wetterer, James, Florida Atlantic University, Harriet L. Wilkes Honors College
- Abstract/Description
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The cardiac ventricles release brain natriuretic peptide (BNP) when the cardiomyocytes are exceptionally stressed. Past research has indicated that BNP can be a used as a prognostic indicator in heart failure patients (Doust et al., 2005). The hypothesis is that higher BNP readings will result in a shorter amount of time that the patient has to live. 210 patients with a heart condition were admitted to the Hospice of Palm Beach County and had their blood drawn to determine their BNP level;...
Show moreThe cardiac ventricles release brain natriuretic peptide (BNP) when the cardiomyocytes are exceptionally stressed. Past research has indicated that BNP can be a used as a prognostic indicator in heart failure patients (Doust et al., 2005). The hypothesis is that higher BNP readings will result in a shorter amount of time that the patient has to live. 210 patients with a heart condition were admitted to the Hospice of Palm Beach County and had their blood drawn to determine their BNP level; however, only 35 patients qualified for the final analysis. The 35 patients had BNP readings ranging from 63 pg/ml to 50000 pg/ml with the average being 6620 pg/ml, whereas the normal range is <100 pg/ml. The time between the last BNP reading and the date of death ranged from 1 day to 732 days with the average being 118 days; furthermore, the trend indicated that the higher the BNP level the shorter the patient had to live which agrees with the hypothesis.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00042
- Format
- Document (PDF)
- Title
- DENTAL FEAR IN ADULTS.
- Creator
- Patel, Meera, Wetterer, James, Florida Atlantic University, Harriet L. Wilkes Honors College
- Abstract/Description
-
Many people suffer a certain degree of dental fear, commonly brought on by an earlier negative experience or by anticipated pain. Dental fear may prevent people from receiving necessary treatment, ultimately worsening their health. To investigate how dental fear is related to age, the origin of dental fear, and preference of treatment options, a self-administered research survey was conducted. The results indicate younger participants claim a lower degree of dental fear in comparison to older...
Show moreMany people suffer a certain degree of dental fear, commonly brought on by an earlier negative experience or by anticipated pain. Dental fear may prevent people from receiving necessary treatment, ultimately worsening their health. To investigate how dental fear is related to age, the origin of dental fear, and preference of treatment options, a self-administered research survey was conducted. The results indicate younger participants claim a lower degree of dental fear in comparison to older participants. Results also showed both negative experience and anticipated pain as origins of dental fear for individuals. Participants also responded positively to music therapy in the waiting rooms/operatory rooms. Lastly, regardless of age and degree of dental fear, respondents preferred receiving both pharmaceutical and psychological treatment options. Future studies could investigate more on preventative care in dental offices and create treatment options based on sole individuals, age groups, origins of dental fear, and effectiveness.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00038
- Format
- Document (PDF)
- Title
- Ethical Issues Concerning “Savior Offspring.”.
- Creator
- Dorcin, Jemima, Wetterer, James, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
-
Tissue transplantation is a procedure used to treat a wide range of medical disorders. Suitable tissue for transplant, however, is often in short supply. Thus, some people conceive offspring for the sole purpose of harvesting compatible tissue, e.g., for transplantation of multipotent hematopoietic stem cells in a sibling or parent. A 2004 survey found that most Americans approve of using genetic testing of in vitro fertilized embryos to allow for the selective implantation of an embryo with...
Show moreTissue transplantation is a procedure used to treat a wide range of medical disorders. Suitable tissue for transplant, however, is often in short supply. Thus, some people conceive offspring for the sole purpose of harvesting compatible tissue, e.g., for transplantation of multipotent hematopoietic stem cells in a sibling or parent. A 2004 survey found that most Americans approve of using genetic testing of in vitro fertilized embryos to allow for the selective implantation of an embryo with compatible tissue for use in a sick older sibling. However, while using stem cells from the umbilicus of a newborn for medical treatments is relatively well accepted, using from tissue from an aborted fetus remains controversial. In my thesis, I examine the ethical issues that arise from the use of tissue from "savior offspring" in medicine, employing both survey tools as well as literature review. When the values were added from their perspective categories, the P-values indicate that age, gender, religion and political affiliation had no effect on the how the survey was answered.
Show less - Date Issued
- 2021
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00167
- Format
- Document (PDF)
- Title
- FLORAL INVENTORY AND HISTORICAL ANALYSIS OF THE FAU ECOLOGICAL PRESERVE.
- Creator
- Mnayarji, Hannah, Wetterer, James, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
-
The ecological site at the Boca Raton campus of Florida Atlantic University, a 0.3 𝑘𝑚2 natural preserve site, is an excellent study in the effects of human disturbance at natural sites. A floral inventory was conducted using stratified sampling of macro plots to determine changes in biodiversity, nonnative species ratios, and wetland species ratios compared to a similar 1990 study. It was found that the site was 25.56% less biodiverse and contained 18.47% more nonnative species in the past...
Show moreThe ecological site at the Boca Raton campus of Florida Atlantic University, a 0.3 𝑘𝑚2 natural preserve site, is an excellent study in the effects of human disturbance at natural sites. A floral inventory was conducted using stratified sampling of macro plots to determine changes in biodiversity, nonnative species ratios, and wetland species ratios compared to a similar 1990 study. It was found that the site was 25.56% less biodiverse and contained 18.47% more nonnative species in the past thirty years. The percentage of wetland species found decreased 32.80% and upland species have increased by 19.86% in the same time period. These results are consistent with ecological trends found in natural sites in South Florida, a result of human alteration of the land in the past century.
Show less - Date Issued
- 2023
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00265
- Format
- Document (PDF)
- Title
- FLORAL SURVEY AND SPECIES CHECKLIST OF FRENCHMAN’S FOREST.
- Creator
- Elkins, Jessica, Wetterer, James, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
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Frenchman’s Forest Natural Area in Palm Beach Gardens, Florida, is a 172-acre (70-hectare) preserve that includes diverse ecosystems, including scrub flatwoods, pine flatwoods, wet flatwoods, and swamp. Earlier floral inventories of this site listed 477 plant species. For my thesis, I surveyed plants in Frenchman’s Forest and compiled a list of plant species documented in Frenchman’s Forest in 2022-2023 based on photographs posted to the iNaturalist website. I found that most of the plant...
Show moreFrenchman’s Forest Natural Area in Palm Beach Gardens, Florida, is a 172-acre (70-hectare) preserve that includes diverse ecosystems, including scrub flatwoods, pine flatwoods, wet flatwoods, and swamp. Earlier floral inventories of this site listed 477 plant species. For my thesis, I surveyed plants in Frenchman’s Forest and compiled a list of plant species documented in Frenchman’s Forest in 2022-2023 based on photographs posted to the iNaturalist website. I found that most of the plant species I documented, a total of 179 plant species, include 37 native and eight non-native species not previously listed. These eight non-native species are described further in detail on their invasive status and how they made their way into the preserve.
Show less - Date Issued
- 2023
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00250
- Format
- Document (PDF)
- Title
- GEOGRAPHIC DISTRIBUTION OF SPINY BACKED ORB WEAVER (Gasteracantha cancriformis) COLOR MORPHS IN THE AMERICAS.
- Creator
- King, Samuel, Wetterer, James, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
-
The spiny-backed orb weaver, Gasteracantha cancriformis, is widely distributed in the Americas. Females are recognizable by their crab-like back plate with six spines. The back plate may be white, red, yellow, or black, and the spines may be red or black. I analyzed the geographic distribution of various color morphs using geo-tagged photographs posted to the iNaturalist website. I found great differences in which color morphs are most prominent in certain areas. For example, morphs with...
Show moreThe spiny-backed orb weaver, Gasteracantha cancriformis, is widely distributed in the Americas. Females are recognizable by their crab-like back plate with six spines. The back plate may be white, red, yellow, or black, and the spines may be red or black. I analyzed the geographic distribution of various color morphs using geo-tagged photographs posted to the iNaturalist website. I found great differences in which color morphs are most prominent in certain areas. For example, morphs with white back and red spines are dominant in the Florida peninsula, yet appear to be almost nonexistent in South America. This analysis may be useful in further research to determine what genetic and/or environmental factors influence this geographic distribution.
Show less - Date Issued
- 2023
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00260
- Format
- Document (PDF)
- Title
- Possible Threat of Stinging Ants to Captive Wildlife at Busch Wildlife Sanctuary in Florida.
- Creator
- Bewley, Anne, Wetterer, James, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
-
Several species of stinging ants are known to attack vertebrates. In March and July 2018, I conducted ant surveys using tuna baits at Busch Wildlife Sanctuary (BWS), in Jupiter, Florida, to assess possible threats to captive animals posed by such ants. BWS rehabilitates native Florida vertebrates that are injured or orphaned and houses others that cannot be released back into the wild. Of the 13 ant species found, two may pose a threat to the animals at BWS: the little fire ant (Wasmannia...
Show moreSeveral species of stinging ants are known to attack vertebrates. In March and July 2018, I conducted ant surveys using tuna baits at Busch Wildlife Sanctuary (BWS), in Jupiter, Florida, to assess possible threats to captive animals posed by such ants. BWS rehabilitates native Florida vertebrates that are injured or orphaned and houses others that cannot be released back into the wild. Of the 13 ant species found, two may pose a threat to the animals at BWS: the little fire ant (Wasmannia auropunctata) and the red imported fire ant (Solenopsis invicta). W. auropunctata, known for stinging the eyes of vertebrates, was the most prevalent species, found at 40% of the baits. S. invicta, known for its powerful sting, occurred at 7% baits. Facilities that house animals outdoors, such as zoos and wildlife rehab centers, should take care to ensure the animals are kept safe from possible attack by ants.
Show less - Date Issued
- 2019
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00123
- Format
- Document (PDF)
- Title
- SPREAD OF AN EXOTIC TRAPJAW ANT ANOCHETUS MAYRI IN SOUTH FLORIDA.
- Creator
- Bryant, Andrew M., Wetterer, James, Florida Atlantic University, Harriet L. Wilkes Honors College
- Abstract/Description
-
Anochetus mayri is a widespread New World species, ranging from South and Central America and the West Indies, north to Florida and the Bahamas. Published records of A. mayri outside of the tropics come from six sites in Florida and two in the Bahamas . The northernmost published record of A. mayri came from the Pine Jog Environmental Learning Center in West Palm Beach, Florida, collected in 2002 in pine and oak litter samples. I examined whether A. mayri was also present in surrounding areas...
Show moreAnochetus mayri is a widespread New World species, ranging from South and Central America and the West Indies, north to Florida and the Bahamas. Published records of A. mayri outside of the tropics come from six sites in Florida and two in the Bahamas . The northernmost published record of A. mayri came from the Pine Jog Environmental Learning Center in West Palm Beach, Florida, collected in 2002 in pine and oak litter samples. I examined whether A. mayri was also present in surrounding areas with similar environmental conditions. I found A. mayri in pine litter at other sites in Palm Beach County, but I did not find this species in similar habitats in Lee County. Additional unpublished records indicate that A. mayri is widespread in deep pine litter in Florida north to Indian River County and West to Highlands County.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00008
- Format
- Document (PDF)
- Title
- Spread of the Invasive Brown Basilisk, Basiliscus vittatus, in Florida.
- Creator
- Wallington, John, Wetterer, James, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
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The brown basilisk, Basiliscus vittatus, is large lizard native to coastal lowlands from central Mexico to Ecuador. In 1976, this species was first discovered in southern Florida, and it has been spreading since. My thesis documents the spread of B. vittatus through southern Florida using published and unpublished records. I mapped a total of 545 records of B. vittatus in Florida: 73 from published records, 15 from my own observations, and 457 from photographs uploaded to iNaturalist....
Show moreThe brown basilisk, Basiliscus vittatus, is large lizard native to coastal lowlands from central Mexico to Ecuador. In 1976, this species was first discovered in southern Florida, and it has been spreading since. My thesis documents the spread of B. vittatus through southern Florida using published and unpublished records. I mapped a total of 545 records of B. vittatus in Florida: 73 from published records, 15 from my own observations, and 457 from photographs uploaded to iNaturalist. Published reports of B. vittatus have been reported from 11 Florida counties (Miami-Dade, Broward, Palm Beach, Martin, St. Lucie, Indian River, Monroe, Collier, Lee, Hendry, and Manatee). In addition, there have been additional unpublished photographic records uploaded to iNaturalist from two more counties (Pinellas and Brevard). These additions expand the known northern range of B. vittatus on both the East and West coasts of Florida.
Show less - Date Issued
- 2019
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00131
- Format
- Document (PDF)
- Title
- Stinging Ants at Gopher Tortoise Burrows.
- Creator
- Viluan, Valerie, Wetterer, James, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
-
Several predatory ant species are known to attack, injure, and even kill vertebrates. Perhaps the most notorious of these are the red imported fire ant, Solenopsis invicta and the little fire ant, Wasmannia auropunctata. In areas where they invade, both are most common in disturbed habitats. Solenopsis invicta often dominates open, grassy areas, while Wasmannia auropunctata more often dominates in forested areas. This study compares the distribution of ant species, including Solenopsis...
Show moreSeveral predatory ant species are known to attack, injure, and even kill vertebrates. Perhaps the most notorious of these are the red imported fire ant, Solenopsis invicta and the little fire ant, Wasmannia auropunctata. In areas where they invade, both are most common in disturbed habitats. Solenopsis invicta often dominates open, grassy areas, while Wasmannia auropunctata more often dominates in forested areas. This study compares the distribution of ant species, including Solenopsis invicta and Wasmannia auropunctata at the burrows of Gopher Tortoises at the Abacoa Greenway located in Jupiter, Florida. Wasmannia auropunctata replaced Solenopsis invicta as the dominating species at our study site in 2021, compared to the results gathered by Rich Jones in 2013. Although both species are not selective with their targets, this shift in pattern could result in a difference of injuries to the Greenway’s inhabitants and should be considered a potential threat in future wildlife schemes.
Show less - Date Issued
- 2021
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00163
- Format
- Document (PDF)
- Title
- TARGETING CANCER STEM CELLS USING ONCOLYTIC ADENOVIRUSES.
- Creator
- Rodriguez Suarez, Michelle, Wetterer, James, Florida Atlantic University, Harriet L. Wilkes Honors College
- Abstract/Description
-
Cancer stem cells play a significant role in both cancer resurgence and progression. Because of this, it is essential to target cancer stem cells when treating cancer. Unfortunately, these cells can evade the cytotoxic effects of standard cancer therapeutics such as chemo- and radiotherapy. Oncolytic adenoviruses have emerged as a therapeutic that is capable of successfully eliminating cancer stem cells. These viruses can be engineered to target specific cell surface markers on the surface of...
Show moreCancer stem cells play a significant role in both cancer resurgence and progression. Because of this, it is essential to target cancer stem cells when treating cancer. Unfortunately, these cells can evade the cytotoxic effects of standard cancer therapeutics such as chemo- and radiotherapy. Oncolytic adenoviruses have emerged as a therapeutic that is capable of successfully eliminating cancer stem cells. These viruses can be engineered to target specific cell surface markers on the surface of cancer stem cells for infection. After infection, they can hijack the cell’s replication machinery to produce new progeny that will eventually lyse the cell. There are limitations to this therapeutic, most importantly that these viruses cannot hide themselves from the host’s immune system that recognizes them as a threat and eliminates them. However, various studies have provided encouraging results that demonstrate the effectiveness of these adenoviruses both in vitro and in vivo when injected intratumorally
Show less - Date Issued
- 2020
- PURL
- http://purl.flvc.org/fau/fd/FA00013665
- Format
- Document (PDF)
- Title
- TERRESTRIAL ISOPODS (ISOPODA: ONISCIDEA) OF THE ROBERT J. HUCKSHORN ARBORETUM IN JUPITER, FLORIDA.
- Creator
- Quesnel, Julie D., Wetterer, James, Florida Atlantic University, Harriet L. Wilkes Honors College
- Abstract/Description
-
Many terrestrial isopod species (Isopoda) are very tolerant of human disturbance and are common in synanthropic habitats of urban and suburban areas. I surveyed terrestrial isopod species in the Robert J. Huckshorn Arboretum on the Jupiter campus of Florida Atlantic University. This small arboretum (4003 m2) includes a variety of native trees and plants, potentially providing diverse resources for isopods. I found a surprisingly rich isopod fauna, totaling five species all in the suborder...
Show moreMany terrestrial isopod species (Isopoda) are very tolerant of human disturbance and are common in synanthropic habitats of urban and suburban areas. I surveyed terrestrial isopod species in the Robert J. Huckshorn Arboretum on the Jupiter campus of Florida Atlantic University. This small arboretum (4003 m2) includes a variety of native trees and plants, potentially providing diverse resources for isopods. I found a surprisingly rich isopod fauna, totaling five species all in the suborder Oniscidea, which have been identified as: Atlantoscia floridana (Van Name, 1940), Trichorhina tomentosa (Budde-Lund, 1893), Nagurus cristatus (Dollfus, 1889), Venezillo parvus (Budde-Lund, 1885), and Porcellionides pruinosus (Brandt, 1833). Two (A. floridana and V. parvus) are considered native to Florida, while three (T. tomentosa, N. cristatus and P. pruinosus) are non-native.
Show less - Date Issued
- 2019
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00118
- Format
- Document (PDF)
- Title
- The Efficacy of Vaccines for SARS.CoV-2.
- Creator
- Ilamadi, Kartikk Musiri, Wetterer, James, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
-
Coronavirus disease 2019, also known as the COVID-19, is the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This disease is first identified in Wuhan, China and has spread across the world causing a pandemic. With the majority of countries shutting down and the infection spreading exponentially, countries raced to find safe and effective vaccines. Nearly a year after the first confirmed case in the United States, vaccines were ready to be administered. The...
Show moreCoronavirus disease 2019, also known as the COVID-19, is the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This disease is first identified in Wuhan, China and has spread across the world causing a pandemic. With the majority of countries shutting down and the infection spreading exponentially, countries raced to find safe and effective vaccines. Nearly a year after the first confirmed case in the United States, vaccines were ready to be administered. The three major vaccines in the United States were Pfizer- BioNTech, Johnson and Johnson and the Moderna Vaccines. The Pfizer-BioNTech and the Moderna required two doses whereas the Johnson and Johnson required only one dose. Vaccines around the world were created and administered at an alarming rate, However, it is still insufficient, as only 5% of the global population has been administered as of April 9, 2021
Show less - Date Issued
- 2021
- PURL
- http://purl.flvc.org/fau/fd/FAUHT00152
- Format
- Document (PDF)
- Title
- THE MOST EFFECTIVE TREATMENT FOR CANINE INTERVERTEBRAL DISC DISEASE.
- Creator
- Kruisland, Gillian Breanne, Wetterer, James, Florida Atlantic University, Harriet L. Wilkes Honors College
- Abstract/Description
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Intervertebral disc disease, or IVDD, involves damage to the discs between vertebrae in the spinal column of vertebrates. The disease is progressive and has a significant genetic component as well as influences from the patient’s lifestyle. This thesis examines IVDD in canines, evaluating the cause, currently available and under research treatment options, and considers future research into mitigating the severity of disease progression. Results suggest that with current knowledge, a...
Show moreIntervertebral disc disease, or IVDD, involves damage to the discs between vertebrae in the spinal column of vertebrates. The disease is progressive and has a significant genetic component as well as influences from the patient’s lifestyle. This thesis examines IVDD in canines, evaluating the cause, currently available and under research treatment options, and considers future research into mitigating the severity of disease progression. Results suggest that with current knowledge, a combination of surgical correction and conservative management yields the best outcome for the patient, decreasing in effectiveness as the disease progresses. Novel treatment options include cell-based, gene, and growth factor therapies that have greater potential with severe cases. This paper suggests targeting the root of the problem to minimize the extent of treatment needed. Educating breeders and pet owners to catch the early onset of the disease will not only minimize detriment to the patient but also increase the number of cases seen by veterinarians, which will allow a greater understanding of the disease’s mechanisms and increased knowledge for laboratory work. The One Health concept allows the transfer of knowledge of the disease between human and veterinary medicine, which should be pushed to further expand the research of IVDD.
Show less - Date Issued
- 2020
- PURL
- http://purl.flvc.org/fau/fd/FA00013660
- Format
- Document (PDF)