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Title: ASSESSING METHODS AND TOOLS TO IMPROVE REPORTING, INCREASE TRANSPARENCY, AND REDUCE FAILURES IN MACHINE LEARNING APPLICATIONS IN HEALTHCARE.
Creator: Garbin, Christian, Marques, Oge, Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Artificial intelligence (AI) had a few false starts – the AI winters of the 1970s and 1980s. We are now in what looks like an AI summer. There are many useful applications of AI in the field. But there are still unfulfilled promises and outright failures. From self-driving cars that work only in constrained cases, to medical image analysis products that would replace radiologists but never did, we still struggle to translate successful research into successful real-world applications. The...
Show moreArtificial intelligence (AI) had a few false starts – the AI winters of the 1970s and 1980s. We are now in what looks like an AI summer. There are many useful applications of AI in the field. But there are still unfulfilled promises and outright failures. From self-driving cars that work only in constrained cases, to medical image analysis products that would replace radiologists but never did, we still struggle to translate successful research into successful real-world applications. The software engineering community has accumulated a large body of knowledge over the decades on how to develop, release, and maintain products. AI products, being software products, benefit from some of that accumulated knowledge, but not all of it. AI products diverge from traditional software products in fundamental ways: their main component is not a specific piece of code, written for a specific purpose, but a generic piece of code, a model, customized by a training process driven by hyperparameters and a dataset. Datasets are usually large and models are opaque. We cannot directly inspect them as we can inspect the code of traditional software products. We need other methods to detect failures in AI products.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013580
Subject Headings: Machine learning, Artificial intelligence, Healthcare
Format: Document (PDF)

Title: SPATIAL NETWORK BIG DATA APPROACHES TO EMERGENCY MANAGEMENT INFORMATION SYSTEMS.
Creator: Herschelman, Roxana M., Yang, KwangSoo, Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Emergency Management Information Systems (EMIS) are defined as a set of tools that aid decision-makers in risk assessment and response for significant multi-hazard threats and disasters. Over the past three decades, EMIS have grown in importance as a major component for understanding, managing, and governing transportation-related systems. To increase resilience against potential threats, the main goal of EMIS is to timely utilize spatial and network datasets about (1) locations of hazard...
Show moreEmergency Management Information Systems (EMIS) are defined as a set of tools that aid decision-makers in risk assessment and response for significant multi-hazard threats and disasters. Over the past three decades, EMIS have grown in importance as a major component for understanding, managing, and governing transportation-related systems. To increase resilience against potential threats, the main goal of EMIS is to timely utilize spatial and network datasets about (1) locations of hazard areas (2) shelters and resources, (3) and how to respond to emergencies. The main concern about these datasets has always been the very large size, variety, and update rate required to ensure the timely delivery of useful emergency information and response for disastrous events. Another key issue is that the information should be concise and easy to understand, but at the same time very descriptive and useful in the case of emergency or disaster. Advancement in EMIS is urgently needed to develop fundamental data processing components for advanced spatial network queries that clearly and succinctly deliver critical information in emergencies. To address these challenges, we investigate Spatial Network Database Systems and study three challenging Transportation Resilience problems: producing large scale evacuation plans, identifying major traffic patterns during emergency evacuations, and identifying the highest areas in need of resources.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013576
Subject Headings: Emergency management, Big data, Emergency management--Information technology
Format: Document (PDF)

Title: CONNECTED MULTI-DOMAIN AUTONOMY AND ARTIFICIAL INTELLIGENCE: AUTONOMOUS LOCALIZATION, NETWORKING, AND DATA CONFORMITY EVALUATION.
Creator: Tountas, Konstantinos, Pados, Dimitris, Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: The objective of this dissertation work is the development of a solid theoretical and algorithmic framework for three of the most important aspects of autonomous/artificialintelligence (AI) systems, namely data quality assurance, localization, and communications. In the era of AI and machine learning (ML), data reign supreme. During learning tasks, we need to ensure that the training data set is correct and complete. During operation, faulty data need to be discovered and dealt with to...
Show moreThe objective of this dissertation work is the development of a solid theoretical and algorithmic framework for three of the most important aspects of autonomous/artificialintelligence (AI) systems, namely data quality assurance, localization, and communications. In the era of AI and machine learning (ML), data reign supreme. During learning tasks, we need to ensure that the training data set is correct and complete. During operation, faulty data need to be discovered and dealt with to protect from -potentially catastrophic- system failures. With our research in data quality assurance, we develop new mathematical theory and algorithms for outlier-resistant decomposition of high-dimensional matrices (tensors) based on L1-norm principal-component analysis (PCA). L1-norm PCA has been proven to be resistant to irregular data-points and will drive critical real-world AI learning and autonomous systems operations in the future. At the same time, one of the most important tasks of autonomous systems is self-localization. In GPS-deprived environments, localization becomes a fundamental technical problem. State-of-the-art solutions frequently utilize power-hungry or expensive architectures, making them difficult to deploy. In this dissertation work, we develop and implement a robust, variable-precision localization technique for autonomous systems based on the direction-of-arrival (DoA) estimation theory, which is cost and power-efficient. Finally, communication between autonomous systems is paramount for mission success in many applications. In the era of 5G and beyond, smart spectrum utilization is key.. In this work, we develop physical (PHY) and medium-access-control (MAC) layer techniques that autonomously optimize spectrum usage and minimizes intra and internetwork interference.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013617
Subject Headings: Artificial intelligence, Machine learning, Tensor algebra
Format: Document (PDF)

Title: NETWORK FEATURE ENGINEERING AND DATA SCIENCE ANALYTICS FOR CYBER THREAT INTELLIGENCE.
Creator: Wheelus, Charles, Zhu, Xingquan, Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: While it is evident that network services continue to play an ever-increasing role in our daily lives, it is less evident that our information infrastructure requires a concerted, well-conceived, and fastidiously executed strategy to remain viable. Government agencies, Non-Governmental Organizations (\NGOs"), and private organizations are all targets for malicious online activity. Security has deservedly become a serious focus for organizations that seek to assume a more proactive posture; in...
Show moreWhile it is evident that network services continue to play an ever-increasing role in our daily lives, it is less evident that our information infrastructure requires a concerted, well-conceived, and fastidiously executed strategy to remain viable. Government agencies, Non-Governmental Organizations (\NGOs"), and private organizations are all targets for malicious online activity. Security has deservedly become a serious focus for organizations that seek to assume a more proactive posture; in order to deal with the many facets of securing their infrastructure. At the same time, the discipline of data science has rapidly grown into a prominent role, as once purely theoretical machine learning algorithms have become practical for implementation. This is especially noteworthy, as principles that now fall neatly into the field of data science has been contemplated for quite some time, and as much as over two hundred years ago. Visionaries like Thomas Bayes [18], Andrey Andreyevich Markov [65], Frank Rosenblatt [88], and so many others made incredible contributions to the field long before the impact of Moore's law [92] would make such theoretical work commonplace for practical use; giving rise to what has come to be known as "Data Science".
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013620
Subject Headings: Cyber security, Computer security, Information infrastructure, Predictive analytics
Format: Document (PDF)

Title: MACHINE LEARNING DEMODULATOR ARCHITECTURES FOR POWER-LIMITED COMMUNICATIONS.
Creator: Gorday, Paul E., Nurgun, Erdol, Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: The success of deep learning has renewed interest in applying neural networks and other machine learning techniques to most fields of data and signal processing, including communications. Advances in architecture and training lead us to consider new modem architectures that allow flexibility in design, continued learning in the field, and improved waveform coding. This dissertation examines neural network architectures and training methods suitable for demodulation in power-limited...
Show moreThe success of deep learning has renewed interest in applying neural networks and other machine learning techniques to most fields of data and signal processing, including communications. Advances in architecture and training lead us to consider new modem architectures that allow flexibility in design, continued learning in the field, and improved waveform coding. This dissertation examines neural network architectures and training methods suitable for demodulation in power-limited communication systems, such as those found in wireless sensor networks. Such networks will provide greater connection to the world around us and are expected to contain orders of magnitude more devices than cellular networks. A number of standard and proprietary protocols span this space, with modulations such as frequency-shift-keying (FSK), Gaussian FSK (GFSK), minimum shift keying (MSK), on-off-keying (OOK), and M-ary orthogonal modulation (M-orth). These modulations enable low-cost radio hardware with efficient nonlinear amplification in the transmitter and noncoherent demodulation in the receiver.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013511
Subject Headings: Deep learning, Machine learning--Technique, Demodulators, Wireless sensor networks, Computer network architectures
Format: Document (PDF)

Title: HPCC based Platform for COPD Readmission Risk Analysis with implementation of Dimensionality reduction and balancing techniques.
Creator: Jain, Piyush, Agarwal, Ankur, Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Hospital readmission rates are considered to be an important indicator of quality of care because they may be a consequence of actions of commission or omission made during the initial hospitalization of the patient, or as a consequence of poorly managed transition of the patient back into the community. The negative impact on patient quality of life and huge burden on healthcare system have made reducing hospital readmissions a central goal of healthcare delivery and payment reform efforts....
Show moreHospital readmission rates are considered to be an important indicator of quality of care because they may be a consequence of actions of commission or omission made during the initial hospitalization of the patient, or as a consequence of poorly managed transition of the patient back into the community. The negative impact on patient quality of life and huge burden on healthcare system have made reducing hospital readmissions a central goal of healthcare delivery and payment reform efforts. In this study, we will be proposing a framework on how the readmission analysis and other healthcare models could be deployed in real world and a Machine learning based solution which uses patients discharge summaries as a dataset to train and test the machine learning model created. Current systems does not take into consideration one of the very important aspect of solving readmission problem by taking Big data into consideration. This study also takes into consideration Big data aspect of solutions which can be deployed in the field for real world use. We have used HPCC compute platform which provides distributed parallel programming platform to create, run and manage applications which involves large amount of data. We have also proposed some feature engineering and data balancing techniques which have shown to greatly enhance the machine learning model performance. This was achieved by reducing the dimensionality in the data and fixing the imbalance in the dataset. The system presented in this study provides a real world machine learning based predictive modeling for reducing readmissions which could be templatized for other diseases.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013560
Subject Headings: Machine learning, Big data, Patient Readmission, Hospitals--Admission and discharge--Data processing, High performance computing
Format: Document (PDF)

Title: NEURALSYNTH - A NEURAL NETWORK TO FPGA COMPILATION FRAMEWORK FOR RUNTIME EVALUATION.
Creator: Lanham, Grant Jr, Hallstrom, Jason O., Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Artificial neural networks are increasing in power, with attendant increases in demand for efficient processing. Performance is limited by clock speed and degree of parallelization available through multi-core processors and GPUs. With a design tailored to a specific network, a field-programmable gate array (FPGA) can be used to minimize latency without the need for geographically distributed computing. However, the task of programming an FPGA is outside the realm of most data scientists....
Show moreArtificial neural networks are increasing in power, with attendant increases in demand for efficient processing. Performance is limited by clock speed and degree of parallelization available through multi-core processors and GPUs. With a design tailored to a specific network, a field-programmable gate array (FPGA) can be used to minimize latency without the need for geographically distributed computing. However, the task of programming an FPGA is outside the realm of most data scientists. There are tools to program FPGAs from a high level description of a network, but there is no unified interface for programmers across these tools. In this thesis, I present the design and implementation of NeuralSynth, a prototype Python framework which aims to bridge the gap between data scientists and FPGA programming for neural networks. My method relies on creating an extensible Python framework that is used to automate programming and interaction with an FPGA. The implementation includes a digital design for the FPGA that is completed by a Python framework. Programming and interacting with the FPGA does not require leaving the Python environment. The extensible approach allows multiple implementations, resulting in a similar workflow for each implementation. For evaluation, I compare the results of my implementation with a known neural network framework.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013533
Subject Headings: Artificial neural networks, Neural networks (Computer science)--Design, Field programmable gate arrays, Python (Computer program language)
Format: Document (PDF)

Title: MULTIFACETED EMBEDDING LEARNING FOR NETWORKED DATA AND SYSTEMS.
Creator: Shi, Min, Tang, Yufei, Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Network embedding or representation learning is important for analyzing many real-world applications and systems, i.e., social networks, citation networks and communication networks. It targets at learning low-dimensional vector representations of nodes with preserved graph structure (e.g., link relations) and content (e.g., texts) information. The derived node representations can be directly applied in many downstream applications, including node classification, clustering and visualization....
Show moreNetwork embedding or representation learning is important for analyzing many real-world applications and systems, i.e., social networks, citation networks and communication networks. It targets at learning low-dimensional vector representations of nodes with preserved graph structure (e.g., link relations) and content (e.g., texts) information. The derived node representations can be directly applied in many downstream applications, including node classification, clustering and visualization. In addition to the complex network structures, nodes may have rich non structure information such as labels and contents. Therefore, structure, label and content constitute different aspects of the entire network system that reflect node similarities from multiple complementary facets. This thesis focuses on multifaceted network embedding learning, which aims to efficiently incorporate distinct aspects of information such as node labels and node contents for cooperative low-dimensional representation learning together with node topology.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013516
Subject Headings: Embedded computer systems, Neural networks (Computer science), Network embedding, Machine learning
Format: Document (PDF)

Title: TOWARDS A SECURITY REFERENCE ARCHITECTURE FOR NETWORK FUNCTION VIRTUALIZATION.
Creator: Alnaim, Abdulrahman K., Fernandez, Eduardo B., Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Network Function Virtualization (NFV) is an emerging technology that transforms legacy hardware-based network infrastructure into software-based virtualized networks. Instead of using dedicated hardware and network equipment, NFV relies on cloud and virtualization technologies to deliver network services to its users. These virtualized network services are considered better solutions than hardware-based network functions because their resources can be dynamically increased upon the consumer’s...
Show moreNetwork Function Virtualization (NFV) is an emerging technology that transforms legacy hardware-based network infrastructure into software-based virtualized networks. Instead of using dedicated hardware and network equipment, NFV relies on cloud and virtualization technologies to deliver network services to its users. These virtualized network services are considered better solutions than hardware-based network functions because their resources can be dynamically increased upon the consumer’s request. While their usefulness can’t be denied, they also have some security implications. In complex systems like NFV, the threats can come from a variety of domains due to it containing both the hardware and the virtualize entities in its infrastructure. Also, since it relies on software, the network service in NFV can be manipulated by external entities like third-party providers or consumers. This leads the NFV to have a larger attack surface than the traditional network infrastructure. In addition to its own threats, NFV also inherits security threats from its underlying cloud infrastructure. Therefore, to design a secure NFV system and utilize its full potential, we must have a good understanding of its underlying architecture and its possible security threats. Up until now, only imprecise models of this architecture existed. We try to improve this situation by using architectural modeling to describe and analyze the threats to NFV. Architectural modeling using Patterns and Reference Architectures (RAs) applies abstraction, which helps to reduce the complexity of NFV systems by defining their components at their highest level. The literature lacks attempts to implement this approach to analyze NFV threats. We started by enumerating the possible threats that may jeopardize the NFV system. Then, we performed an analysis of the threats to identify the possible misuses that could be performed from them. These threats are realized in the form of misuse patterns that show how an attack is performed from the point of view of attackers. Some of the most important threats are privilege escalation, virtual machine escape, and distributed denial-of-service. We used a reference architecture of NFV to determine where to add security mechanisms in order to mitigate the identified threats. This produces our ultimate goal, which is building a security reference architecture for NFV.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013435
Subject Headings: Computer network architectures--Safety measures, Virtual computer systems, Computer networks, Modeling, Computer
Format: Document (PDF)

Title: A REFERENCE ARCHITECTURE FOR NETWORK FUNCTION VIRTUALIZATION.
Creator: Alwakeel, Ahmed M., Fernandez, Eduardo B., Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Cloud computing has provided many services to potential consumers, one of these services being the provision of network functions using virtualization. Network Function Virtualization is a new technology that aims to improve the way we consume network services. Legacy networking solutions are different because consumers must buy and install various hardware equipment. In NFV, networks are provided to users as a software as a service (SaaS). Implementing NFV comes with many benefits, including...
Show moreCloud computing has provided many services to potential consumers, one of these services being the provision of network functions using virtualization. Network Function Virtualization is a new technology that aims to improve the way we consume network services. Legacy networking solutions are different because consumers must buy and install various hardware equipment. In NFV, networks are provided to users as a software as a service (SaaS). Implementing NFV comes with many benefits, including faster module development for network functions, more rapid deployment, enhancement of the network on cloud infrastructures, and lowering the overall cost of having a network system. All these benefits can be achieved in NFV by turning physical network functions into Virtual Network Functions (VNFs). However, since this technology is still a new network paradigm, integrating this virtual environment into a legacy environment or even moving all together into NFV reflects on the complexity of adopting the NFV system. Also, a network service could be composed of several components that are provided by different service providers; this also increases the complexity and heterogeneity of the system. We apply abstract architectural modeling to describe and analyze the NFV architecture. We use architectural patterns to build a flexible NFV architecture to build a Reference Architecture (RA) for NFV that describe the system and how it works. RAs are proven to be a powerful solution to abstract complex systems that lacks semantics. Having an RA for NFV helps us understand the system and how it functions. It also helps us to expose the possible vulnerabilities that may lead to threats toward the system. In the future, this RA could be enhanced into SRA by adding misuse and security patterns for it to cover potential threats and vulnerabilities in the system. Our audiences are system designers, system architects, and security professionals who are interested in building a secure NFV system.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013434
Subject Headings: Virtual computer systems, Cloud computing, Computer network architectures, Computer networks
Format: Document (PDF)

Title: COMPARISON OF PRE-TRAINED CONVOLUTIONAL NEURAL NETWORK PERFORMANCE ON GLIOMA CLASSIFICATION.
Creator: Andrews, Whitney Angelica Johanna, Furht, Borko, Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Gliomas are an aggressive class of brain tumors that are associated with a better prognosis at a lower grade level. Effective differentiation and classification are imperative for early treatment. MRI scans are a popular medical imaging modality to detect and diagnosis brain tumors due to its capability to non-invasively highlight the tumor region. With the rise of deep learning, researchers have used convolution neural networks for classification purposes in this domain, specifically pre...
Show moreGliomas are an aggressive class of brain tumors that are associated with a better prognosis at a lower grade level. Effective differentiation and classification are imperative for early treatment. MRI scans are a popular medical imaging modality to detect and diagnosis brain tumors due to its capability to non-invasively highlight the tumor region. With the rise of deep learning, researchers have used convolution neural networks for classification purposes in this domain, specifically pre-trained networks to reduce computational costs. However, with various MRI modalities, MRI machines, and poor image scan quality cause different network structures to have different performance metrics. Each pre-trained network is designed with a different structure that allows robust results given specific problem conditions. This thesis aims to cover the gap in the literature to compare the performance of popular pre-trained networks on a controlled dataset that is different than the network trained domain.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013450
Subject Headings: Gliomas, Neural networks (Computer science), Deep Learning, Convolutional neural networks
Format: Document (PDF)

Title: SMARTPHONE BASED SICKLE CELL DISEASE DETECTION AND ITS TREATMENT MONITORING FOR POINT-OF-CARE SETTINGS.
Creator: Ilyas, Shazia, Asghar, Waseem, Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: The majority of Sickle Cell Disease (SCD) prevalence is found in Sub-Saharan Africa, where 80% of the world’s population who suffer from this disease are born. Due to a lack of diagnosis and early treatments, 50-90% of these children will die before they reach the age of five. Current methods used for diagnosing SCD are based on hemoglobin analysis such as capillary electrophoresis, ion-exchange high-performance liquid chromatography, and isoelectric focusing. They require expensive...
Show moreThe majority of Sickle Cell Disease (SCD) prevalence is found in Sub-Saharan Africa, where 80% of the world’s population who suffer from this disease are born. Due to a lack of diagnosis and early treatments, 50-90% of these children will die before they reach the age of five. Current methods used for diagnosing SCD are based on hemoglobin analysis such as capillary electrophoresis, ion-exchange high-performance liquid chromatography, and isoelectric focusing. They require expensive laboratory equipment and are not feasible in these low-resource countries. It is, therefore, imperative to develop an alternative and cost-effective method for diagnosing and monitoring of SCD. This thesis aims to address the development and evaluation of a smartphone-based optical setup for the detection of SCD. This innovative technique can potentially be applied for low cost and accurate diagnosis of SCD and improve disease management in resource-limited settings where the disease exhibits a high prevalence. This Point-of-Care (POC) based device offers the potential to improve SCD diagnosis and patient care by providing a portable and cost effective device that requires minimal training to operate and analyze.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013475
Subject Headings: Anemia, Sickle Cell, Point-of-Care Systems, Sickle cell anemia--Treatment, Sickle cell anemia--Diagnosis, Smartphones
Format: Document (PDF)

Title: META-LEARNING AND ENSEMBLE METHODS FOR DEEP NEURAL NETWORKS.
Creator: Liu, Feng, Dingding, Wang, Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Deep Neural Networks have been widely applied in many different applications and achieve significant improvement over classical machine learning techniques. However, training a neural network usually requires large amount of data, which is not guaranteed in some applications such as medical image classification. To address this issue, people propose to implement meta learning and ensemble learning techniques to make deep learning trainers more powerful. This thesis focuses on using deep...
Show moreDeep Neural Networks have been widely applied in many different applications and achieve significant improvement over classical machine learning techniques. However, training a neural network usually requires large amount of data, which is not guaranteed in some applications such as medical image classification. To address this issue, people propose to implement meta learning and ensemble learning techniques to make deep learning trainers more powerful. This thesis focuses on using deep learning equipped with meta learning and ensemble learning to study specific problems. We first propose a new deep learning based method for suggestion mining. The major challenges of suggestion mining include cross domain issue and the issues caused by unstructured and highly imbalanced data structure. To overcome these challenges, we propose to apply Random Multi-model Deep Learning (RMDL) which combines three different deep learning architectures (DNNs, RNNs and CNNs) and automatically selects the optimal hyper parameter to improve the robustness and flexibility of the model. Our experimental results on the SemEval-2019 competition Task 9 data sets demonstrate that our proposed RMDL outperforms most of the existing suggestion mining methods.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013481
Subject Headings: Neural networks (Computer science), Deep learning, Neural Networks in Applications, Machine learning--Technique
Format: Document (PDF)

Title: CEREBROSPINAL FLUID SHUNT SYSTEM WITH AUTO-FLOW REGULATION.
Creator: Mutlu, Caner, Asghar, Waseem, Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: A cerebrospinal fluid (CSF) shunt system is used for treatment of hydrocephalus and abnormal intracranial pressure (ICP) conditions. Mostly a shunt system is placed under skin for creating a low resistance pathway between intracranial space and appropriate discharge sites within body by doing so excess CSF volume can exit the intracranial space. Displaced intracranial CSF volume normally results in lowered ICP. Thereby, a CSF shunt can manage ICP. In a healthy person, normal ICP is primarily...
Show moreA cerebrospinal fluid (CSF) shunt system is used for treatment of hydrocephalus and abnormal intracranial pressure (ICP) conditions. Mostly a shunt system is placed under skin for creating a low resistance pathway between intracranial space and appropriate discharge sites within body by doing so excess CSF volume can exit the intracranial space. Displaced intracranial CSF volume normally results in lowered ICP. Thereby, a CSF shunt can manage ICP. In a healthy person, normal ICP is primarily maintained by CSF production and reabsorption rate as a natural tendency of body. If intracranial CSF volume starts increasing due to under reabsorption, this mostly results in raised ICP. Abnormal ICP can be treated by discharging excess CSF volume via use of a shunt system. Once a shunt system is placed subcutaneously, a patient is expected to live a normal life. However, shunt failure as well as flow regulatory problems are major issues with current passive shunt systems which leaves patients with serious consequences of under-/over CSF drainage condition. In this research, a shunt system is developed which is resistant to most shunt-related causes of under-/over CSF drainage. This has been made possible via use of an on-board medical monitoring (diagnostic) and active flow control mechanism. The developed shunt system, in this research, has full external ventricular drainage (EVD) capability. Further miniaturization will make it possible for an implantable shunt.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013489
Subject Headings: Cerebrospinal Fluid Shunts
Format: Document (PDF)

Title: DEVELOPMENT OF POINT-OF-CARE ASSAYS FOR DISEASE DIAGNOSTIC AND TREATMENT MONITORING FOR RESOURCE CONSTRAINED SETTINGS.
Creator: Sher, Mazhar, Asghar, Waseem, Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: This thesis aims to address the challenges of the development of cost-effective and rapid assays for the accurate counting of CD4+ T cells and quantification of HIV-1 viral load for resource-constrained settings. The lack of such assays has severely affected people living in disease prevalent areas. CD4+ T cells count information plays a vital role in the effective management of HIV-1 disease. Here, we present a flow-free magnetic actuation platform that uses antibody-coated magnetic beads to...
Show moreThis thesis aims to address the challenges of the development of cost-effective and rapid assays for the accurate counting of CD4+ T cells and quantification of HIV-1 viral load for resource-constrained settings. The lack of such assays has severely affected people living in disease prevalent areas. CD4+ T cells count information plays a vital role in the effective management of HIV-1 disease. Here, we present a flow-free magnetic actuation platform that uses antibody-coated magnetic beads to efficiently capture CD4+ T cells from a 30 μL drop of whole blood. On-chip cell lysate electrical impedance spectroscopy has been utilized to quantify the isolated CD4 cells. The developed assay has a limit of detection of 25 cells per μL and provides accurate CD4 counts in the range of 25–800 cells per μL. The whole immunoassay along with the enumeration process is very rapid and provides CD4 quantification results within 5 min time frame. The assay does not require off-chip sample preparation steps and minimizes human involvement to a greater extent. The developed impedance-based immunoassay has the potential to significantly improve the CD4 enumeration process especially for POC settings.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013495
Subject Headings: Point-of-care testing, Diagnostic tests, Immunoassay, HIV-1, Microfluidic devices
Format: Document (PDF)

Title: 2006-2007 Program Review Computer Science and Engineering.
Creator: Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Florida Atlantic University Departmental Dashboard Indicators. Department program reviews for College of Engineering and Computer Science, Florida Atlantic University.
Date Issued: 2006-2007
PURL: http://purl.flvc.org/fau/fd/FA00007722
Subject Headings: Florida Atlantic University -- History
Format: Document (PDF)

Title: 2006-2007 Program Review Electrical Engineering.
Creator: Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Florida Atlantic University Departmental Dashboard Indicators. Department program reviews for College of Engineering and Computer Science, Florida Atlantic University.
Date Issued: 2006-2007
PURL: http://purl.flvc.org/fau/fd/FA00007723
Subject Headings: Florida Atlantic University -- History
Format: Document (PDF)

Title: 2009-2010 Program Review Computer and Electrical Engineering and Computer Science.
Creator: Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Florida Atlantic University Departmental Dashboard Indicators. Department program reviews for College of Engineering and Computer Science, Florida Atlantic University.
Date Issued: 2009-2010
PURL: http://purl.flvc.org/fau/fd/FA00007727
Subject Headings: Florida Atlantic University -- History
Format: Document (PDF)

Title: 2009-2010 Program Review Computer and Electrical Engineering and Computer Science.
Creator: Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Florida Atlantic University Departmental Dashboard Indicators. Department program reviews for College of Engineering and Computer Science, Florida Atlantic University.
Date Issued: 2010-2011
PURL: http://purl.flvc.org/fau/fd/FA00007730
Subject Headings: Florida Atlantic University -- History
Format: Document (PDF)

Title: 2009-2010 Program Review Computer and Electrical Engineering and Computer Science.
Creator: Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description: Florida Atlantic University Departmental Dashboard Indicators. Department program reviews for College of Engineering and Computer Science, Florida Atlantic University.
Date Issued: 2012-2013
PURL: http://purl.flvc.org/fau/fd/FA00007733
Subject Headings: Florida Atlantic University -- History
Format: Document (PDF)

Legacy FAU Student Theses and Dissertations 1967-2006 (405)	+ -
Current FAU Student Theses and Dissertations 2007 to date (267)	+ -
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