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Title: IN MEDICAL EVIDENCE AND PRACTICE, WHAT LEVEL OF UNCERTAINTY IS ACCEPTABLE?.
Creator: Levine, Hannah, Kennedy, Ashley, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: This thesis addresses the level of uncertainty in medical evidence and practice and asks if this level is acceptable. Current medical standards consider randomized controlled trials (RCTs) as the best, and most certain, form of evidence. Similarly, medical practice largely relies on differential diagnosis and diagnostic testing to diagnose patients. I will argue that RCTs as well as differential diagnosis and diagnostic testing contribute to uncertainty in medical practice. In the former,...
Show moreThis thesis addresses the level of uncertainty in medical evidence and practice and asks if this level is acceptable. Current medical standards consider randomized controlled trials (RCTs) as the best, and most certain, form of evidence. Similarly, medical practice largely relies on differential diagnosis and diagnostic testing to diagnose patients. I will argue that RCTs as well as differential diagnosis and diagnostic testing contribute to uncertainty in medical practice. In the former, uncertainty stems from lack of representation, elimination of confounding factors, among other issues; while in the latter, uncertainty originates from technological limitations, similarity or variability in presentation, and number of diagnostic possibilities. I will argue that uncertainty in medical evidence and practice can and should be reduced. This can be done by expanding RCT testing and improving it by adding required mechanistic evidence, and by furthering research into better diagnostic technology and training.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FAUHT00084
Format: Document (PDF)

Title: THE EFFECTS OF CASH ON CHANGES IN HOME PRICE: A STUDY OF CASH OFFERS ON RESIDENTIAL REAL ESTATE IN JUPITER FLORIDA.
Creator: Venugopalan, Sanjay, Nur-tegin, Kanybek, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Real estate transactions are fraught with risks and costs. Transaction delay and failure are risks directly linked to loan approval. Real estate sellers tend to prefer the proceeds from the sale of their home with immediacy and surety rather than with a delay but waiting for loan approval causes such a delay. Using an ordinary least squares regression analysis, I assess whether home sellers are willing to concede discounts to buyers who offer to pay cash, to avoid the risks of transaction...
Show moreReal estate transactions are fraught with risks and costs. Transaction delay and failure are risks directly linked to loan approval. Real estate sellers tend to prefer the proceeds from the sale of their home with immediacy and surety rather than with a delay but waiting for loan approval causes such a delay. Using an ordinary least squares regression analysis, I assess whether home sellers are willing to concede discounts to buyers who offer to pay cash, to avoid the risks of transaction failure and delay of payment. I claim that, in contrast to a loan, a cash offer reduces the risk of a failed transaction, and this reduced risk is reflected as a discount on the price of the house greater than any discounts for loan-based transactions. This paper will also assess the magnitude of any discounts as a percentage of the home’s last list price on the market.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003729
Format: Document (PDF)

Title: “WHAT ROLE DO DENTAL PRESCRIPTIONS PLAY IN THE OPIOID CRISIS?”.
Creator: Shah, Palak, Kennedy, Ashley, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: According to the Center for Disease Control and Prevention (CDC), 47,000 individuals died in 2017 due to an opioid overdose. Further, dentists are more likely to prescribe immediate-release opioids than other healthcare providers. In the late 1990s, dentists were responsible for 15.5% of prescriptions for immediate-release opioids, and 8% of these prescriptions in 2009. In this thesis I examine the reasons for this, including the ways in which a patient’s sex, age, race, and ethnicity play a...
Show moreAccording to the Center for Disease Control and Prevention (CDC), 47,000 individuals died in 2017 due to an opioid overdose. Further, dentists are more likely to prescribe immediate-release opioids than other healthcare providers. In the late 1990s, dentists were responsible for 15.5% of prescriptions for immediate-release opioids, and 8% of these prescriptions in 2009. In this thesis I examine the reasons for this, including the ways in which a patient’s sex, age, race, and ethnicity play a role in dental prescriptions, and conclude that dentists do not consistently use the Prescription Drug Monitoring Program (PDMPs) or the guidelines set by the American Dental Association. I argue that to help to prevent opioid misuse and abuse dentists should do a risk assessment before prescribing opioids.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003722
Format: Document (PDF)

Title: HOW COMMISSION RATES IMPACT REAL ESTATE AGENT’S PERFORMANCE: AN ECONOMIC REGRESSION OF AGENT PERFORMANCE IN JUPITER.
Creator: Vandenbraak, Tracy, Nur-tegin, Kanybek, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Real estate agents charge their clients a percentage on every property sold and this percentage, or commission, can range from five to six percent. The reason for this difference is unclear. Using an ordinary least squares regression, I attempt to find a connection between real estate agent performance and the amount commission which he or she charges. The premium agent effect assumes that more efficient, or “successful”, agents charge more for their services because they are overall better...
Show moreReal estate agents charge their clients a percentage on every property sold and this percentage, or commission, can range from five to six percent. The reason for this difference is unclear. Using an ordinary least squares regression, I attempt to find a connection between real estate agent performance and the amount commission which he or she charges. The premium agent effect assumes that more efficient, or “successful”, agents charge more for their services because they are overall better than the agents who charge a lower commission. Efficiency in this paper is determined by the percent difference in the listing price and sold price as well as the total days the property is on the market. My preliminary results provide strong evidence of the existence of the premium agent effect when agent performance is measured in terms of the percent difference in the listing price and the sold price, but not when measured using the total number of days the property is on the market.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003728
Format: Document (PDF)

Title: RELIGIOUS IDENTITIES: VARIETIES OF COLLECTIVE CONSCIOUSNESS.
Creator: Stanton Kalani , Reilly Alexander, Lanning, Kevin, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: As an interdisciplinary endeavor, the study of consciousness is informed by a variety of scholarly perspectives that, when integrated, deepen our understanding of consciousness as a functional system of semiotic communication. This thesis explores linguistic behavior as a manifestation of collective consciousness via the incorporation of theory from psychology, sociology, and philosophy into an analytical framework for studying consciousness. Using this analytical framework, I present an...
Show moreAs an interdisciplinary endeavor, the study of consciousness is informed by a variety of scholarly perspectives that, when integrated, deepen our understanding of consciousness as a functional system of semiotic communication. This thesis explores linguistic behavior as a manifestation of collective consciousness via the incorporation of theory from psychology, sociology, and philosophy into an analytical framework for studying consciousness. Using this analytical framework, I present an analysis of patterns of linguistic behavior from online religious communitas on reddit.com. I analyze the patterns of linguistic behaviors in this data using tokenization and semantic analysis techniques, revealing the divergent manifestations of identity in each collective consciousness. Ultimately, I find a striking similarity between the language used across all the subreddits, but the differences between them validate the consideration of these as divergent interpretants of collective consciousness.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003723
Format: Document (PDF)

Title: DIETARY ANALYSIS OF THE FLORIDA EAST COAST DIAMONDBACK TERRAPIN ( Malaclemys terrapin tequesta ).
Creator: Torres, Davidsamuel, Moore, Jon, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: The diamondback terrapin ( Malaclemys terrapin ) is the only exclusively estuarine turtle. Terrapins live in coastal mangroves and salt marshes ranging from Massachusetts to Texas. While previous studies have documented the diet of terrapins in temperate salt marshes, the diet of the Florida East Coast terrapin subspecies ( M. terrapin tequesta) living in mangrove habitats is largely unknown. Other diamondback subspecies feed on a variety of prey categories, with plants, gastropods, and...
Show moreThe diamondback terrapin ( Malaclemys terrapin ) is the only exclusively estuarine turtle. Terrapins live in coastal mangroves and salt marshes ranging from Massachusetts to Texas. While previous studies have documented the diet of terrapins in temperate salt marshes, the diet of the Florida East Coast terrapin subspecies ( M. terrapin tequesta) living in mangrove habitats is largely unknown. Other diamondback subspecies feed on a variety of prey categories, with plants, gastropods, and bivalves being the most dominant, depending on the subspecies. For my thesis research, I examined the diet of M. terrapin tequesta from the Indian River Lagoon by analyzing 13 terrapin fecal samples. The remains of decapod crustaceans occurred in all 13 samples and made up 96.3% of the fecal mass; a small amount of vegetation, bivalves, gastropods, insects, and debris also occurred in many of the samples. This is the only study to find crustaceans to be the dominant food of a terrapin subspecies. This difference probably relates to preferred prey availability in mangrove habitats.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003726
Format: Document (PDF)

Title: ENDOCRINE DISRUPTING AGENTS AND UTERINE DEVELOPMENT.
Creator: Tolentino, Bernadeth, Moore, Jon, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Breast cancer is the second leading cause of cancer deaths in women, causing more than 40,000 deaths per year. Tamoxifen is the most widely prescribed Selective Estrogen Receptor Modulator, as it has been shown to enable prevention of 50% of breast cancers. It is also prescribed to prevent cancer remission after surgery, chemotherapy, or radiation. It is frequently used amongst women that have a high risk for breast cancer prior to diagnosis as a cancer preventative drug. Unfortunately,...
Show moreBreast cancer is the second leading cause of cancer deaths in women, causing more than 40,000 deaths per year. Tamoxifen is the most widely prescribed Selective Estrogen Receptor Modulator, as it has been shown to enable prevention of 50% of breast cancers. It is also prescribed to prevent cancer remission after surgery, chemotherapy, or radiation. It is frequently used amongst women that have a high risk for breast cancer prior to diagnosis as a cancer preventative drug. Unfortunately, tamoxifen can cause damage to developing embryos if taken during pregnancy, and can lead to serious side effects, including endometrial cancer. The purpose of this work was to examine how tamoxifen induces uterine proliferation using an in vivo gene knockdown screen using shRNAmir viral technology. The shRNAmir library will identify epigenetic regulator proteins that associate with the estrogen receptor to stimulate uterine proliferative genes, allowing us to understand the extent at which tamoxifen leads to the development of cancerous cells.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003724
Format: Document (PDF)

Title: ASSESSING THE DEVELOPMENT OF TOLERANCE TO AMPHETAMINE USING C. ELEGANS.
Creator: Torres Valladares, Dayana, Carvelli, Lucia, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Amphetamine (AMPH) is a potent psychostimulant and is a known substance of abuse, also used to treat attention deficit/hyperactivity disorder and narcolepsy. AMPH acts at the dopaminergic neurons through the dopamine transporter (DAT), and it leads to DAT-mediated efflux, resulting in an overall increase of dopamine (DA) in the synaptic cleft. It is known that exposure to AMPH may cause sensitization and/or tolerance. However, the molecular mechanisms underlying tolerance to AMPH are not yet...
Show moreAmphetamine (AMPH) is a potent psychostimulant and is a known substance of abuse, also used to treat attention deficit/hyperactivity disorder and narcolepsy. AMPH acts at the dopaminergic neurons through the dopamine transporter (DAT), and it leads to DAT-mediated efflux, resulting in an overall increase of dopamine (DA) in the synaptic cleft. It is known that exposure to AMPH may cause sensitization and/or tolerance. However, the molecular mechanisms underlying tolerance to AMPH are not yet well understood. Because DA has an inhibitory effect in C. elegans’ locomotion, the animals fail to sustain their normal swimming behavior when exposed to AMPH and paralyze within few minutes. This behavior, termed Swimming Induced Paralysis (SWIP), was used to test whether C. elegans develops sensitization and/or tolerance to AMPH. Our results show that repetitive exposures to AMPH reduced SWIP suggesting that C. elegans develops tolerance to AMPH after repeated exposures.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003725
Format: Document (PDF)

Title: CASSAVA AND TROPICAL DIABETES.
Creator: Rich, Praewpailin, Kennedy, Ashley, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Cassava is the third-largest source of food carbohydrates in the tropics and is a major staple food among developing countries. Cassava contains cyanogenic glycosides which turn into cyanide and are toxic to the body when ingested in a high content. Cyanide poisoning causes many symptoms including severe abdominal pain which is also one of the symptoms occurring in patients with pancreatitis. Tropical diabetes or fibrocalculous pancreatitis diabetes mellitus is secondary to tropical...
Show moreCassava is the third-largest source of food carbohydrates in the tropics and is a major staple food among developing countries. Cassava contains cyanogenic glycosides which turn into cyanide and are toxic to the body when ingested in a high content. Cyanide poisoning causes many symptoms including severe abdominal pain which is also one of the symptoms occurring in patients with pancreatitis. Tropical diabetes or fibrocalculous pancreatitis diabetes mellitus is secondary to tropical pancreatitis which is a form of non-alcoholic chronic calcific pancreatitis found primarily in tropical regions. The symptoms include severe abdominal pain. In this study, I will hypothesize that there is a link between early life ingestion of cassava, inadequate protein intake, tropical chronic pancreatitis and tropical diabetes.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003721
Format: Document (PDF)

Title: TESTING FOR CHYTRID FUNGUS INFECTION IN SOUTHEAST FLORIDA CRUSTACEANS.
Creator: Turn, Jeffrey, Trivigno, Catherine, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Batrachochytrium dendrobatidis and Batrachochytrium salamandrivorans, chytrid fungi (Chytridiomycota) species known for their lethality in amphibians by chytridiomycosis, were tested for in crayfish (Procambarus alleni and Procambarus fallax) and eastern grass shrimp (Palaemonetes paludosus). From 2019 to 2020, these crustaceans were gathered from 21 sites in southeastern Florida and were frozen, dissected, and swabbed with sterile swabs. Samples from the same site were pooled together and...
Show moreBatrachochytrium dendrobatidis and Batrachochytrium salamandrivorans, chytrid fungi (Chytridiomycota) species known for their lethality in amphibians by chytridiomycosis, were tested for in crayfish (Procambarus alleni and Procambarus fallax) and eastern grass shrimp (Palaemonetes paludosus). From 2019 to 2020, these crustaceans were gathered from 21 sites in southeastern Florida and were frozen, dissected, and swabbed with sterile swabs. Samples from the same site were pooled together and sent to the San Diego Zoo Amphibian Lab for TaqMan PCR to verify the presence of chytrid fungi. Excluding the positive control, the results from the TaqMan PCR returned negative for the presence of either chytrid fungi species. This could indicate that these chytrid fungi are not yet present at the sites tested, or that these crayfish and shrimp species do not act as vectors for chytrid fungus in Southeast Florida. Alternatively, chytrid infection may be seasonal in Southeast Florida.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003727
Format: Document (PDF)

Title: PLATO’S REJECTION OF POETRY: A DEFENSE OF FALSEHOODS AND IMITATIONS IN THE REPUBLIC.
Creator: Garcia-Diaz, Jeremy O.N., Baima, Nicholas, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: In various Platonic dialogues, Socrates appears to discredit myth and fiction. Most notably in the Republic, he seems to argue that poetry is harmful due to its false nature and its relation to imitation which misleads those who experience it about the nature of the good. Yet, in many of these same dialogues, Socrates makes multiple appeals to myths, either using the previously constructed myths of others, or constructing stories of his own. Given that the dialogues themselves are...
Show moreIn various Platonic dialogues, Socrates appears to discredit myth and fiction. Most notably in the Republic, he seems to argue that poetry is harmful due to its false nature and its relation to imitation which misleads those who experience it about the nature of the good. Yet, in many of these same dialogues, Socrates makes multiple appeals to myths, either using the previously constructed myths of others, or constructing stories of his own. Given that the dialogues themselves are fictionalized conversations written by Plato, a student of Socrates, he himself cannot categorically reject fictional stories. I argue that Plato’s critical examination and restriction of myth and poetry is not an absolute rejection. Rather, Plato is rejecting that poetry which ignorantly depicts falsehoods. This ignorance cultivates mistaken beliefs of what is most important; the good, right, and virtuous, and ultimately causes disharmony and harm in the souls of its audience.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003708
Format: Document (PDF)

Title: Phylogeography of the Burrowing Four O’clock, Okenia hypogaea (Nyctaginaceae).
Creator: Depatie, Trinity Hope, Wetterer, James K., Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: The burrowing four o’clock or beach peanut, Okenia hypogaea (Nyctaginaceae), is a vine found on beaches of southeast Florida, Mexico, and Central America. This species was described from Mexico in 1830 and discovered in Florida near Miami in 1903. Since then, O. hypogaea has been considered a rare native species in Florida. For my thesis, I proposed to test the hypothesis that O. hypogaea is exotic to Florida by comparing the genetic diversity of populations in Florida with populations in...
Show moreThe burrowing four o’clock or beach peanut, Okenia hypogaea (Nyctaginaceae), is a vine found on beaches of southeast Florida, Mexico, and Central America. This species was described from Mexico in 1830 and discovered in Florida near Miami in 1903. Since then, O. hypogaea has been considered a rare native species in Florida. For my thesis, I proposed to test the hypothesis that O. hypogaea is exotic to Florida by comparing the genetic diversity of populations in Florida with populations in Mexico. The first gene I examined was identical across all populations tested in Mexico and Florida. I am currently working on examining a more variable gene.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003706
Format: Document (PDF)

Title: Proving Godel's Theorem, a set-theoretical approach.
Creator: Lohier, Jean, McGovern, Warren, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Before Godel's incompleteness theorems, logicians such as Bertrand Russel and Alfred Whitehead pursued an ideal axiomatic system which would have created a reliable framework to successfully prove or refute every mathematical sentence. Godel proved that such systems can never be created. In fact, Godel's incompleteness theorems establish that axiomatic systems that are complex enough to formulate arithmetic can never generate a proof of all the logical statements that are expressible inside...
Show moreBefore Godel's incompleteness theorems, logicians such as Bertrand Russel and Alfred Whitehead pursued an ideal axiomatic system which would have created a reliable framework to successfully prove or refute every mathematical sentence. Godel proved that such systems can never be created. In fact, Godel's incompleteness theorems establish that axiomatic systems that are complex enough to formulate arithmetic can never generate a proof of all the logical statements that are expressible inside of them. According to the first incompleteness theorem, there are constructible mathematical sentences that can never be proven to be true or false using the axioms and the logical rules of the system. Furthermore, the second incompleteness theorem argues that the consistency of all axiomatic systems which contain Peano or Robinson arithmetic can never be determined using the rules and the proof mechanisms available in the system.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003715
Format: Document (PDF)

Title: THE HISTORY, CHEMISTRY, AND REGULATION OF COSMETICS.
Creator: Cook, Carly E., Chandrasekhar, Chitra, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Cosmetics have played an integral part in beautifying humankind for tens of thousands of years. The practice of people enhancing their natural features dates back several millennia before written text to ancient Egyptian and other early civilizations. Throughout time, these augmentation methods have been studied and perfected to create what is now a multibillion-dollar industry. The earliest forms of cosmetics derived from locally available natural resources but over time transformed to...
Show moreCosmetics have played an integral part in beautifying humankind for tens of thousands of years. The practice of people enhancing their natural features dates back several millennia before written text to ancient Egyptian and other early civilizations. Throughout time, these augmentation methods have been studied and perfected to create what is now a multibillion-dollar industry. The earliest forms of cosmetics derived from locally available natural resources but over time transformed to incorporate synthetic and potentially harmful substances including lead, formaldehyde, and benzophenone. The objective of this thesis is to investigate the timeline of cosmetic use and to inquire into the compulsion to use cosmetics for embellishing the natural look, the introduction of artificial chemicals into cosmetics, the minimal protective legislative guidelines currently in place, and the necessary reforms required to ensure the safety of the consumer.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003701
Format: Document (PDF)

Title: GEOGRAPHIC DISTRIBUTION OF OKENIA HYPOGAEA AND SOIL ANALYSIS ALONG THE COAST OF JOHN D. MACARTHUR BEACH STATE PARK.
Creator: King, Makenna, Moore, Jon, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Okenia hypogaea is a rare vine-like dune plant found only in Mexico and five counties on Florida’s southeast coast, from St. Lucie to Miami-Dade County. At John D. MacArthur Beach State Park, GPS coordinates of all Okenia hypogaea within the park were collected to create a map. I repeated this process following substantial beach erosion, caused by Hurricane Dorian, to compare growth patterns and geographic distribution. This data can be utilized by park officials when managing this species....
Show moreOkenia hypogaea is a rare vine-like dune plant found only in Mexico and five counties on Florida’s southeast coast, from St. Lucie to Miami-Dade County. At John D. MacArthur Beach State Park, GPS coordinates of all Okenia hypogaea within the park were collected to create a map. I repeated this process following substantial beach erosion, caused by Hurricane Dorian, to compare growth patterns and geographic distribution. This data can be utilized by park officials when managing this species. Soil analysis along the same 1.3-mile stretch of beach was done to evaluate environmental parameters impacting Okenia’s distribution and growth. Ten samples collected in the North region and ten in the South region of the beach were compared to determine any differences in their chemical composition that may affect Okenia hypogaea distribution. The tests performed on the soil measured pH, salinity, concentrations of various metals, petroleum products, and polycyclic aromatic hydrocarbons.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003712
Format: Document (PDF)

Title: HEMATOLOGY OF THE FLORIDA EAST COAST DIAMONDBACK TERRAPIN (Malaclemys terrapin tequesta).
Creator: Martin, Isabella M., Moore, Jon, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Diamondback terrapins (Malaclemys terrapin) are present in brackish water along the United States’ eastern coast, ranging from Massachusetts to Texas. The Florida east coast diamondback terrapin (M. t. tequesta) is the subspecies found in the Indian River Lagoon in southeast Florida. Very little is known about this subspecies, and not much hematological work has been done with diamondback terrapins in general. Hematology can provide further insight into terrapin health. Thus, the purpose of...
Show moreDiamondback terrapins (Malaclemys terrapin) are present in brackish water along the United States’ eastern coast, ranging from Massachusetts to Texas. The Florida east coast diamondback terrapin (M. t. tequesta) is the subspecies found in the Indian River Lagoon in southeast Florida. Very little is known about this subspecies, and not much hematological work has been done with diamondback terrapins in general. Hematology can provide further insight into terrapin health. Thus, the purpose of this study is to establish baseline hematological data for M. t. tequesta using blood protein electrophoresis and a basic reptile chemistry panel. Blood samples were drawn from wild diamondback terrapins and percent cell volume calculated. The samples were then centrifuged, frozen, and delivered to the University of Miami Miller School of Medicine for analysis. Results from this project were compared to values established in previous studies that were conducted with the subspecies M. t. terrapin and M. t. rhizophorarum.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003716
Format: Document (PDF)

Title: INCREASING ACCESS TO INSULIN.
Creator: Futral, Cheyanne, Maldonado, Monica, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: As insulin prices have skyrocketed over the past century, a growing number of diabetic patients struggle to afford their medication, specifically insulin. The increase in prices prevent many patients from accessing insulin and result in non-adherence to their prescribed insulin doses, leading to dire health consequences. The purpose of this work is to analyze how the price of insulin increased drastically over time as a result of extended pharmaceutical patents, FDA regulations, and examine...
Show moreAs insulin prices have skyrocketed over the past century, a growing number of diabetic patients struggle to afford their medication, specifically insulin. The increase in prices prevent many patients from accessing insulin and result in non-adherence to their prescribed insulin doses, leading to dire health consequences. The purpose of this work is to analyze how the price of insulin increased drastically over time as a result of extended pharmaceutical patents, FDA regulations, and examine the reason behind the lack of generic insulin alternatives on the market. To make insulin more accessible for diabetic patients, the insulin market must be reformed to encourage the development of biosimilar insulin alternatives, regulate insulin supply chain price increases, and monitor the adherence to insulin of diabetic patients.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003707
Format: Document (PDF)

Title: Native Animals in Muscogee and Seminole Culture: Symbolism, Kinship, and Lessons for Wildlife Conservation in Florida.
Creator: Dennis, Skylar, O’Brien, William, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: This project will assess and define a connection between Florida’s native animal populations and their significance to the environment and the cultures of Florida’s Indigenous Peoples. The main Florida indigenous groups referenced are the Muscogee (Creek) and The Seminole Tribe of Florida. The main points of focus are animal symbology, relationships between native animals and group social structure, kinship relationships, and hunting practices. I also consider the adaptation of these...
Show moreThis project will assess and define a connection between Florida’s native animal populations and their significance to the environment and the cultures of Florida’s Indigenous Peoples. The main Florida indigenous groups referenced are the Muscogee (Creek) and The Seminole Tribe of Florida. The main points of focus are animal symbology, relationships between native animals and group social structure, kinship relationships, and hunting practices. I also consider the adaptation of these practices as cultural diffusion and assimilation occurred between the indigenous groups and early non-indigenous settlers. I include an in-depth discussion about several animals around which the Muscogee Creek created their clans, connecting to creation stories, social structure, and ancestry. The sacred relationships between native animals and peoples goes widely unnoticed by the present-day occupants of Florida; therefore, educating the public on these connections can help them better understand the importance of wildlife preservation and conservation in the state.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003705
Format: Document (PDF)

Title: CREASES AND FOLDS.
Creator: Davis, Amber, Luria, Rachel, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Creases and Folds is a magic realism piece that follows a small family as the three members navigate their fraying connections. The story employs magic realism as a tool through which the son, Teddy, interacts with, influences, and explores the world around him, framing the journey to reconciliation. This thesis project aims to produce a coherent and compelling narrative as its centerpiece and evaluate the work’s place in the established genre.
Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003704
Format: Document (PDF)

Title: Combination of Sulindac and Metformin as a Therapeutic Target in Lung Cancer.
Creator: Butler, Heather, Trivigno, Catherine, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Sulindac is an FDA approved, non-steroidal anti-inflammatory drug that exhibits anti-cancer properties. Metformin is and FDA approved, anti-diabetic drug that also has documented anti-cancer properties. The goal of this project was to explore if a dual-combination of sulindac and metformin in the presence of a chemical oxidizing agent is more effective in killing lung cancer cells while not inducing cell death in normal lung cells. Our data shows that a triple-drug combination of sulindac,...
Show moreSulindac is an FDA approved, non-steroidal anti-inflammatory drug that exhibits anti-cancer properties. Metformin is and FDA approved, anti-diabetic drug that also has documented anti-cancer properties. The goal of this project was to explore if a dual-combination of sulindac and metformin in the presence of a chemical oxidizing agent is more effective in killing lung cancer cells while not inducing cell death in normal lung cells. Our data shows that a triple-drug combination of sulindac, metformin, and tert-butyl hydroperoxide induce significant cell death in lung cancer cells but did not induce significant cell death in normal lung cells.
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Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00003700
Format: Document (PDF)

Criticism and interpretation (30)	+ -
History (26)	+ -
Social aspects (12)	+ -
Wildlife conservation (12)	+ -
Politics and government (11)	+ -

Psychological aspects (11)	+ -
Ecology (10)	+ -
Cellular signal transduction (9)	+ -
Formation (9)	+ -
Cell organelles (8)	+ -
Environmental aspects (8)	+ -
History and criticism (8)	+ -
Law and legislation (8)	+ -
Cytoskeletal proteins (7)	+ -
Philosophy (7)	+ -
Cancer (6)	+ -
Habitat (6)	+ -
Identification (6)	+ -
Microtubules (6)	+ -
Molecular aspects (6)	+ -
Molecular biology (6)	+ -
Political aspects (6)	+ -
Prevention (6)	+ -
Research (6)	+ -
Symbolism in literature (6)	+ -
Age factors (5)	+ -
Aging (5)	+ -
Ants (5)	+ -
Cell division (5)	+ -
Centrosomes (5)	+ -

United States (40)	+ -
Florida (28)	+ -
Latin America (10)	+ -
Jupiter (8)	+ -
Abacoa (6)	+ -

England (5)	+ -
Great Britain (4)	+ -
Japan (3)	+ -
Palm Beach County (3)	+ -
Venezuela (3)	+ -
Europe (2)	+ -
France (2)	+ -
Georgia (2)	+ -
Mexico (2)	+ -
Spain (2)	+ -
Africa (1)	+ -
Arab countries (1)	+ -
Argentina (1)	+ -
Atlanta (1)	+ -
Atlanta (Ga.) (1)	+ -
Australia (1)	+ -
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