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- Title
- Florida Atlantic University 2018 3MT® Three Minute Thesis Championship - Joseph Niederhauser.
- Creator
- Niederhauser, Joseph, Florida Atlantic University
- Abstract/Description
-
The 3MT® competition celebrates the exciting research conducted by graduate students. Developed by The University of Queensland (UQ), the exercise cultivates students’ academic, presentation, and research communication skills. The competition supports the
- Date Issued
- 2019
- PURL
- http://purl.flvc.org/fau/fd/FA00007559
- Subject Headings
- College students --Research --United States.
- Format
- Video file
- Title
- An Examination of the Morphosyntactic Structure of Verb Phrases in Chaldean Neo-Aramaic.
- Creator
- Barile, Paul, Hamilton, Michael
- Abstract/Description
-
This research is an examination of the morphological and syntactical features found within verb phrases of Chaldean Neo-Aramaic, a Semitic language which originates from Mesopotamia. From this examination, a configurational model is proposed, which depicts the grammatical arrangement of these morphosyntactic features during verb phrase formation. Additionally, accompanying this description of the language's verb phrases, a dependency-based approach is taken for the analysis of the language's...
Show moreThis research is an examination of the morphological and syntactical features found within verb phrases of Chaldean Neo-Aramaic, a Semitic language which originates from Mesopotamia. From this examination, a configurational model is proposed, which depicts the grammatical arrangement of these morphosyntactic features during verb phrase formation. Additionally, accompanying this description of the language's verb phrases, a dependency-based approach is taken for the analysis of the language's sentence structure. Such a method departs from traditional perspectives which posit that the concept of a sentence is the compositional result of two distinct linguistic elements: a subject and a predicate (the verb phrase). However, from the analysis of the language, an argument is presented for a reconsideration of the conceptualization of a sentence that would position the verb as the primary element, or nucleus, on which all other occurring elements are either directly or indirectly dependent.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000029
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Assessment of the Long-Term Durability of Recycled Aggregate Concrete.
- Creator
- Martins, Caique, Sobhan, Khaled
- Abstract/Description
-
This study tests the long-term durability that can be developed in concrete batches made with recycled aggregate concrete. Durability is a broad term used to define the resistance of a material to weathering effects, but in this scenario, durability will be defined as a drop in the compressive strength of the concrete. To test this, thermal sensing was used to determine the maturity of the concrete, or in other words how far along the curing process the concrete is. This was then plotted...
Show moreThis study tests the long-term durability that can be developed in concrete batches made with recycled aggregate concrete. Durability is a broad term used to define the resistance of a material to weathering effects, but in this scenario, durability will be defined as a drop in the compressive strength of the concrete. To test this, thermal sensing was used to determine the maturity of the concrete, or in other words how far along the curing process the concrete is. This was then plotted against the corresponding concrete compressive strength to create a relationship that can be exploited to project the later age strength of the concrete. This data is paramount in determining the viability of recycled concrete aggregate because it is a sustainable alternative to other coarse aggregate material, an essential part to making concrete, but its’ properties are largely unknown since they can be highly variable.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000044
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Advertising Research and Strategy: The Role of Creative Thinking Techniques Using Lifestyle Relevance.
- Creator
- Milios, Stasia, Vega, Eliezer, Baker, Heather, Mobley, Naim, Smith, Allen
- Abstract/Description
-
As Vans’ market increases, marketers depend on advertising to reinforce competitive advantage. Our research-in-progress demonstrates the methods we used to research. The information gathered from our focus group suggests that durability and comfort are the main factors when making a purchase. Competitors like Converse and Nike use their market share to persuade their buyers to pay a premium price while Vans focus on durability and the lifestyle the shoes brings to the consumers. Our secondary...
Show moreAs Vans’ market increases, marketers depend on advertising to reinforce competitive advantage. Our research-in-progress demonstrates the methods we used to research. The information gathered from our focus group suggests that durability and comfort are the main factors when making a purchase. Competitors like Converse and Nike use their market share to persuade their buyers to pay a premium price while Vans focus on durability and the lifestyle the shoes brings to the consumers. Our secondary research revealed that millennials are considered the least conservative generation, which implies the rash nature of our target market. With the large growth rate of millennials, their preference pool is strongly influenced by the new wave. In regards to rebranding, vans began using “off the wall” to distance themselves from primarily skating to athleisure wear. Vans are mostly worn in cities with warmer climates to maximize comfort and a feeling of relaxation throughout the day.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000045
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Airbnb Satisfaction Analysis.
- Creator
- Grant, Vladislav, Glaser, Jordan, Behara, Ravi
- Abstract/Description
-
This is an explanatory research study. The purpose of the research is to evaluate performance of the traveling industry through statistical analysis. In the developing world of global economies, people travel on a regular basis. Travelers tend to complain about the Hotel Industry and how it is manipulating prices for their clientele. AirB&B is disrupting the hotel industry by allowing private owners to rent out their properties for short periods of time with less risk. Currently, we have...
Show moreThis is an explanatory research study. The purpose of the research is to evaluate performance of the traveling industry through statistical analysis. In the developing world of global economies, people travel on a regular basis. Travelers tend to complain about the Hotel Industry and how it is manipulating prices for their clientele. AirB&B is disrupting the hotel industry by allowing private owners to rent out their properties for short periods of time with less risk. Currently, we have obtained data to prove that AirB&B is satisfying their customers better than regular hotel industry.
We will be comparing how does the number of bedrooms, the accommodations, the price and minimum stay requirements affecting the overall satisfaction of the traveling clientele. We will attempt to compare this data to how the room type effects the reviews and overall satisfaction to all other hotel ratings.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000038
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Effects of Nonpharmacological Interventions in Older Adults With Dementia: Chair Yoga, Chair-Based Exercise, and Participatory Music Intervention.
- Creator
- Arcay, Victoria, Lopes, Yve, Park, Juyoung
- Abstract/Description
-
This pilot study evaluated the feasibility of having older adults with dementia participate in a nonpharmacological treatment—chair yoga, chair-based exercise, or participatory music intervention—and assessed the effects of the interventions on physical, behavioral and psychological symptoms, general quality of life, and sleep patterns throughout the course of the study. The study employed a three-arm cluster-randomized, longitudinal design. Sites were randomly assigned 1:1:1 to chair yoga,...
Show moreThis pilot study evaluated the feasibility of having older adults with dementia participate in a nonpharmacological treatment—chair yoga, chair-based exercise, or participatory music intervention—and assessed the effects of the interventions on physical, behavioral and psychological symptoms, general quality of life, and sleep patterns throughout the course of the study. The study employed a three-arm cluster-randomized, longitudinal design. Sites were randomly assigned 1:1:1 to chair yoga, chair-based exercise, or music intervention. Twenty-seven participants completed 24 sessions in 12 weeks. We administered evaluation measures at baseline, midline (6 weeks), and post intervention (12 weeks). Repeated-measures analysis of covariance (ANCOVA) was conducted to examine group differences at the collection points, controlling for baseline variability (i.e., gender, age, race/ethnicity) in outcomes.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000027
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Diagnosis of Citrus Greening Disease by qPCR Analysis.
- Creator
- Rocha, Fernando, Zhang, Xing-Hai
- Abstract/Description
-
Citrus greening, also known as Huanglongbing disease, is a phloem restrictive disease that affects orange as well as other citrus trees. The disease is caused by the gram negative bacteria Candidatus Liberibacter asiaticus. The bacteria is transmitted by the Asian psyllid, Diaphorina citri. The bacteria causes the tree to produce small and bitter oranges, the roots shrink and the leaves molt. There is currently no cure for this disease. The best way to manage citrus greening is by removing...
Show moreCitrus greening, also known as Huanglongbing disease, is a phloem restrictive disease that affects orange as well as other citrus trees. The disease is caused by the gram negative bacteria Candidatus Liberibacter asiaticus. The bacteria is transmitted by the Asian psyllid, Diaphorina citri. The bacteria causes the tree to produce small and bitter oranges, the roots shrink and the leaves molt. There is currently no cure for this disease. The best way to manage citrus greening is by removing infected trees, implementing healthy planting material and controlling the psyllid population. Quantitative real time PCR (qPCR) was used to verify whether or not a given orange tree had citrus greening disease. DNA was extracted from leaves from eight trees. A qPCR analysis was performed using a primer with the bacteria DNA. Three trees were successfully diagnosed with citrus greening using this method.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000051
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Dimension Perception.
- Creator
- Vegara, Sebastian, Pitters, Ian, White, Tristan, Knipp, Tammy
- Abstract/Description
-
Three-dimensional computer-generated imagery (CGI) has been the animation industry standard for about two decades. There has been increased research in non-photorealistic rendering (NPR) techniques by industry leaders such as Walt Disney Animation Studios. NPR is computer-generated imagery that is augmented to replicate a distinct art style that deviates from what you would expect to see in a 3D rendering. In this study, subjects are tasked to determine whether a series of animated clips are...
Show moreThree-dimensional computer-generated imagery (CGI) has been the animation industry standard for about two decades. There has been increased research in non-photorealistic rendering (NPR) techniques by industry leaders such as Walt Disney Animation Studios. NPR is computer-generated imagery that is augmented to replicate a distinct art style that deviates from what you would expect to see in a 3D rendering. In this study, subjects are tasked to determine whether a series of animated clips are two-dimensional or three-dimensional. Student participants are pooled into two groups, based on visual art majors and non-visual art majors. Using eye-tracking software, the data will observe if an individual uses visual cues to draw distinctions between two-dimensional and three-dimensional forms, along with how their viewing patterns change for each particular animation as the line between 2D and 3D gets blurred.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000056
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- No more DACA? An Uncertain Future Under the Trump Administration.
- Creator
- Alvarez, Alyssa, Carreño-Lukasik, Gina
- Abstract/Description
-
The Deferred Action for Childhood Arrivals program (DACA) provides temporary relief from deportation and legal work authorization for eligible unauthorized youth in the U.S. In September of 2012, the Obama administration began to allow individuals that entered the country as minors be granted the opportunity of deferred action from deportations and work permits. In 2014, the motion for covering additional immigrants under the act was blocked by the courts, and as of 2018, President Trump...
Show moreThe Deferred Action for Childhood Arrivals program (DACA) provides temporary relief from deportation and legal work authorization for eligible unauthorized youth in the U.S. In September of 2012, the Obama administration began to allow individuals that entered the country as minors be granted the opportunity of deferred action from deportations and work permits. In 2014, the motion for covering additional immigrants under the act was blocked by the courts, and as of 2018, President Trump plans on disbanding DACA as well as the DREAM act, changing the lives of millions who have shaped America. For this research, I conducted a literature review that examines the benefits and limitations of DACA, the emotional and mental effects of being an “illegal” immigrant, and the political views of members of the current U.S. administration that will threaten the lives of many. Finally, I propose a possible research project to further explore this issue.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000026
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Promoting Understanding Through Shared Human Connection in Photographs.
- Creator
- Schayes, Emily, Opalinski, Andra
- Abstract/Description
-
Despite the nursing code of ethics, nurses may stigmatize persons experiencing homelessness, and this can impact the quality of care given. Visual art has the potential to create dialogue and promote social change. However, there is little existing research on how art impacts those observing it. The purpose of this descriptive pilot study was to explore nurses’ perceptions surrounding homelessness by exposing participants to an artistic representation depicting homelessness and shared human...
Show moreDespite the nursing code of ethics, nurses may stigmatize persons experiencing homelessness, and this can impact the quality of care given. Visual art has the potential to create dialogue and promote social change. However, there is little existing research on how art impacts those observing it. The purpose of this descriptive pilot study was to explore nurses’ perceptions surrounding homelessness by exposing participants to an artistic representation depicting homelessness and shared human connection. A deductive, qualitative approach was used to examine positive and negative word use in writings completed by graduate nursing students before and after viewing a photographic exhibit. Findings revealed little change in negative word use and an increase in positive word use. These findings suggest that visual art may have the potential to increase empathy and humanization toward the people depicted.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000053
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Food Offerings at Faith-based Activities for Children/Youth.
- Creator
- Parra Jaimes, Andrea, Gropper, Sareen, Opalinski, Andra
- Abstract/Description
-
Obesity/overweight affects one-third of U.S. children. While the causes are multifactorial, increased consumption of away-from-home (versus at-home) meals has been shown to contribute to higher calorie and fat intakes. This study’s objective was to examine food/beverage provisions at faith-based children/youth events. Direct observation methodology was used for data collection from 10 churches (two to five observations/church) in Southeast FL. Food/beverages served on 31 occasions (26 meals,...
Show moreObesity/overweight affects one-third of U.S. children. While the causes are multifactorial, increased consumption of away-from-home (versus at-home) meals has been shown to contribute to higher calorie and fat intakes. This study’s objective was to examine food/beverage provisions at faith-based children/youth events. Direct observation methodology was used for data collection from 10 churches (two to five observations/church) in Southeast FL. Food/beverages served on 31 occasions (26 meals, 5 non-meals) were documented/analyzed for nutrient content (Food Processor software). Main dishes were mostly pizza and pasta-based casseroles (45%) with white bread/rolls (side dish) (27%). Vegetables (non-potato) were served twice, and fruits five times but seldom eaten. Provided beverages were primarily sugar-sweetened (87%). Desserts/snack-foods were served at 55% of events. Foods were generally high in fat and/or sugar and contributed little to needed fruit / vegetable servings. These findings provide nutritional evidence to initiate dialogues within faith-communities about healthier food provisions at children/youth-related activities.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000047
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- GC-MS Investigation of Fecal Sterols as Indicators of Pollution.
- Creator
- Price, Christopher, Louda, J. William
- Abstract/Description
-
The goal of this experiment is to perfect the method of trimethylsilyl derivatization of fecal steroids Coprostan-3-one and Coprostanol using pyridine & N,O-bis-(trimethylsilyl)-trifluoroacetamide (BSTFA) containing 1% of Trimethylchlorosilane (TMCS). The extraction method for sediments involves Soxhlet extraction followed by saponification. The extraction of water samples will be done by XAD-2 resin or SPE with C18 cartridges and extracted with MeCl2. The primary instrument of this...
Show moreThe goal of this experiment is to perfect the method of trimethylsilyl derivatization of fecal steroids Coprostan-3-one and Coprostanol using pyridine & N,O-bis-(trimethylsilyl)-trifluoroacetamide (BSTFA) containing 1% of Trimethylchlorosilane (TMCS). The extraction method for sediments involves Soxhlet extraction followed by saponification. The extraction of water samples will be done by XAD-2 resin or SPE with C18 cartridges and extracted with MeCl2. The primary instrument of this experiment was a Gas Chromatography- Mass spectroscopy (GC-MS). In addition, a Perkin-Elmer Autosystem GC coupled to a Perkin-Elmer TurboMass Gold mass spectrometer was used, with Helium as the carrier gas. Lastly, this experiment required a computer with Turbomass software version 5.4.2. to analyze samples after derivatization. The results of the GC-MS analysis showed that the methods of derivatization were correct.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000049
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Impact of Functional versus Symbolic Signals on Initial Impressions: Implications for Designing the Look of a Website Homepage to Convey an Outdoorsy Brand Image/Personality for a Lifestyle Brand.
- Creator
- Gordon, Danielle, Llanos, Katherine, Nuhin, Samin, Smith, Allen
- Abstract/Description
-
As competition among brands escalates, marketers seek emerging opportunities to differentiate and position brands and grow a customer base by offering lifestyle brands. Lifestyle branding adds value to consumers by integrating superior functional performance, enabling fuller engagement in lifestyle activities with emotional appeals satisfying psychological desires, such as adventure, excitement, camaraderie, and self-expression. While the importance of both functional performance and...
Show moreAs competition among brands escalates, marketers seek emerging opportunities to differentiate and position brands and grow a customer base by offering lifestyle brands. Lifestyle branding adds value to consumers by integrating superior functional performance, enabling fuller engagement in lifestyle activities with emotional appeals satisfying psychological desires, such as adventure, excitement, camaraderie, and self-expression. While the importance of both functional performance and emotional brand meaning have been justified in the marketing literature, an advertising maxim claimed successful communication required emphasis on one dominant message to create the most persuasive initial impression. Knowing that initial impressions impact consumer judgments of product design form, this study investigated whether functional or symbolic signals created more persuasive initial impressions when used to create the look of a website homepage for an outdoorsy lifestyle brand. The right look of a homepage creates a mood facilitating persuasion. Consent forms and APA Style complied with ethical research standards.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000037
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Molecular Characterization of Hepatozoon (Apicomplexa: Adeleorina) Blood Parasite within the Threatened Gopherus Polyphemus Species.
- Creator
- Eusse, Johanna, Cooney, Brian, Frazier, Evelyn
- Abstract/Description
-
The gopher tortoise (Gopherus polyphemus) is a threatened burrowing chelonian endemic to the Southeastern United States. Gopher tortoises are classified as a keystone species due to their construction of extensive burrows, providing shelter to approximately 362 commensal species. Haemogregarines are the most common hemoparasite species found within reptiles. The genus Hepatozoon sp. (Apicomplexa: Adeleorina) has been discovered within gopher tortoises at Jonathan Dickinson State Park (Jupiter...
Show moreThe gopher tortoise (Gopherus polyphemus) is a threatened burrowing chelonian endemic to the Southeastern United States. Gopher tortoises are classified as a keystone species due to their construction of extensive burrows, providing shelter to approximately 362 commensal species. Haemogregarines are the most common hemoparasite species found within reptiles. The genus Hepatozoon sp. (Apicomplexa: Adeleorina) has been discovered within gopher tortoises at Jonathan Dickinson State Park (Jupiter, Florida). Our research focus is to conduct molecular analysis on the 18S rRNA region of Hepatozoon sp. within blood samples and to determine how this species found is related to other known Hepatozoon species. This molecular characterization study will provide us a better understanding of the existing Hepatozoon blood parasite species within gopher tortoises in South Florida.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000035
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Hydrofracking-on-a-chip: Particle Laden Transport Under High Pressure.
- Creator
- Linares, Natalia, Albrecht, George, Kim, Myeongsub
- Abstract/Description
-
Hydraulic fracturing (hydrofracking) has enabled recovery of natural gas and oil embedded in low permeability reservoirs. Despite its advancement in significant recovery of hydrocarbons not previously accessible from low permeability reservoirs, understanding the particle interactions and injected fluid retraction is lacking. The goal of this project is to investigate fluid dynamics of the fracking fluid (particle-laden flow) under instant fluid injection and withdrawal. We will use a...
Show moreHydraulic fracturing (hydrofracking) has enabled recovery of natural gas and oil embedded in low permeability reservoirs. Despite its advancement in significant recovery of hydrocarbons not previously accessible from low permeability reservoirs, understanding the particle interactions and injected fluid retraction is lacking. The goal of this project is to investigate fluid dynamics of the fracking fluid (particle-laden flow) under instant fluid injection and withdrawal. We will use a microfluidic-based approach in order to visualize a fluid displacement as well as particle-particle interactions in a micromodel that mimics the flow in actual reservoirs. Nanoporous spherical silica particles in diameter of 0.1 mm are going to be utilized in this project. A high-speed visualization tool will characterize the dynamic and complex nature of particle transportation, deposition and their interactions under dynamic flow conditions. In addition, the role of surface properties on these behaviors will be tested.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000042
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Identification of Bottlenose Dolphin Prey Within the IRL, Utilizing Images Collected During Observed Dolphin Feeding Behaviors.
- Creator
- Grell, Kaitlin, Albrecht, Dan, Waldron, Jordan, Katz, Dana, Nelson, Brandy, Murdoch Titcomb, Elizabeth
- Abstract/Description
-
Identification of dolphin prey is fundamental to understanding the ecological function of dolphins within the Indian River Lagoon (IRL), and useful in determining shared resources and associated health risks among dolphins and humans. This study utilized 62 images of dolphin prey documented during observed feeding behaviors from 2003 to 2015 to determine prey of significance. Dolphin prey were comprised of: 44% mullet (Mugil spp.), 11% jack (Caranx spp.), 10% pinfish (Lagodon sp.), and 6.5%...
Show moreIdentification of dolphin prey is fundamental to understanding the ecological function of dolphins within the Indian River Lagoon (IRL), and useful in determining shared resources and associated health risks among dolphins and humans. This study utilized 62 images of dolphin prey documented during observed feeding behaviors from 2003 to 2015 to determine prey of significance. Dolphin prey were comprised of: 44% mullet (Mugil spp.), 11% jack (Caranx spp.), 10% pinfish (Lagodon sp.), and 6.5% menhaden (Brevoortia spp.). The remaining 28.5% of prey were comprised of 11 genera, and no spatial or temporal differences among prey were found. The majority (87%) of the genera of fishes documented as dolphin prey are also targeted by local fisheries for human consumption, bait, and sport. Understanding the prey habits of this apex predator can be useful in determining management and conservation strategies for local fisheries and ecosystems, and identifying possible vectors for bioaccumulation of contaminants.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000039
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Biological Benefit of the mCAT.
- Creator
- Frydman, Sylvia, Yousefzadeh, Matt, Niedernhofer, Laura, Dawson-Scully, Ken
- Abstract/Description
-
Aging is associated with chronic diseases and is attributed to increased morbidity, mortality, and healthcare costs globally. Controversy exists over the root cause(s) of aging, nonetheless, extensive research links increased oxidants and reduced antioxidant buffering capacity with aging. The free radical theory of aging posits that the toxic build-up of free radicals and reactive oxygen species (ROS), promotes oxidative stress and enhances aging. Investigations involving the effect of...
Show moreAging is associated with chronic diseases and is attributed to increased morbidity, mortality, and healthcare costs globally. Controversy exists over the root cause(s) of aging, nonetheless, extensive research links increased oxidants and reduced antioxidant buffering capacity with aging. The free radical theory of aging posits that the toxic build-up of free radicals and reactive oxygen species (ROS), promotes oxidative stress and enhances aging. Investigations involving the effect of mitochondrial-targeted catalase, have proven to be beneficial in reducing ROS and increasing lifespan in naturally aged mice. My project involves investigating the biological benefit of the mCAT transgene and rescue of age-related functional decline in progeroid Ercc1-/∆ mice, an accelerated mouse model of aging. mCAT expression was shown to be largely restricted to the brain, heart, and muscle of mice. mCAT+/-;Ercc1-/∆ mice showed improvements in behavioral tests and health evaluations relative to controls.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000036
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Development and Optimization of AlphaScreen Assay for Discovery of Galectin-1/-3 Inhibitors.
- Creator
- Rivero, Yaima, Fitzgerald, Forrest, Cudic, Mare
- Abstract/Description
-
Galectin-1 is a beta-galactoside-binding protein implicated in regulating apoptosis, cell proliferation and cell differentiation. The objective of our research was to develop and optimize an assay format for the discovery of new inhibitors of galectin-1 using AlphaScreen technology in a competitive binding configuration. Our efforts were hampered by the weak binding affinities of galectin-1 for its binding ligands (μM range). Consequently, the AlphaScreen assay could not have been developed...
Show moreGalectin-1 is a beta-galactoside-binding protein implicated in regulating apoptosis, cell proliferation and cell differentiation. The objective of our research was to develop and optimize an assay format for the discovery of new inhibitors of galectin-1 using AlphaScreen technology in a competitive binding configuration. Our efforts were hampered by the weak binding affinities of galectin-1 for its binding ligands (μM range). Consequently, the AlphaScreen assay could not have been developed at the level that would satisfy the guidelines from the National Chemical Genomics Center. Nevertheless, we have optimized the AlphaScreen assay for galectin-3, another member of galectin family, and screened an FDA approved oncology drug library (n = 101) from the NIH. We identified three possible inhibitors of galectin-3. These compounds showed a positive activity in dose response experiments: bleomycin (IC50 = 25.7 nM), cisplatin (IC50 = 127 nM), and mitoxantrone HCl (IC50 = 662 nM).
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000050
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Exploring the Relationship Between Anxiety and HRV in Parents with Low Income.
- Creator
- Dixon, Derricka, King, Beth, Edwards, Karethy, Barry, Charlotte, Newman, David
- Abstract/Description
-
Over 40 million people in the United States are living in poverty today. The effects of living in disadvantaged circumstances increases the individual’s likelihood of experiencing persistent anxiety, which can lead to chronic health conditions. Studies have associated persistent anxiety with cardiovascular compromise as a result of decreased levels of heart rate variability (HRV). The purpose of this study is to explore the relationship between anxiety and heart rate variability in parents or...
Show moreOver 40 million people in the United States are living in poverty today. The effects of living in disadvantaged circumstances increases the individual’s likelihood of experiencing persistent anxiety, which can lead to chronic health conditions. Studies have associated persistent anxiety with cardiovascular compromise as a result of decreased levels of heart rate variability (HRV). The purpose of this study is to explore the relationship between anxiety and heart rate variability in parents or guardians of children in Head Start, a federally funded program for families with low-incomes. A descriptive correlational design comparing the scores on the PROMIS anxiety tool with HRV as measured by the emWave biometric instrument will be used. The sample consists of 32 participants. Data will be analyzed using bivariate correlations. Increased levels of anxiety and decreased heart rate variability are anticipated outcomes of this study. Findings will assist in identifying health risks in this vulnerable population.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000034
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- First Arctic Under-ice Ocean Walking Laboratory (FAU OWL).
- Creator
- Prescod, Hanifah, Su, Tsung-Chow
- Abstract/Description
-
This study is to design an autonomous underwater robotic laboratory for different missions within the Arctic environment. Missions involve locating natural resources such as oil deposits, determining if the area is a feasible location for deployment of sea and air systems for many operations, and to obtain water and mineral samples to study and monitor the changing Arctic environment. Thus far, we demonstrated the feasibility of an autonomous walking robot that can be used to explore the...
Show moreThis study is to design an autonomous underwater robotic laboratory for different missions within the Arctic environment. Missions involve locating natural resources such as oil deposits, determining if the area is a feasible location for deployment of sea and air systems for many operations, and to obtain water and mineral samples to study and monitor the changing Arctic environment. Thus far, we demonstrated the feasibility of an autonomous walking robot that can be used to explore the Arctic by walking under a sheet of ice. A key component of this is that by controlling the robot’s buoyancy the robot will be capable of walking upside down under a wooden plank. We water proofed a commercially available model robot and carried out the experiment in the Hydrodynamics Laboratory. The preliminary investigation contributes to an internal proposal submitted to I-Sense Internal Fund Program.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000048
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)