Current Search: Leucocytes (x)
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Title
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Recovery of functional human lymphocytes from Leukotrap* filters.
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Creator
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Longley, Ross E., Stewart, D., Harbor Branch Oceanographic Institute
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Date Issued
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1989
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PURL
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http://purl.flvc.org/FCLA/DT/3353830
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Subject Headings
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Lymphocytes, Leucocytes, Blood--Filtration
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Format
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Document (PDF)
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Title
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Analysis of gene expression profiles from normal and chronic lymphocytic leukemia white blood cells.
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Creator
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Chapp, Robert James., Florida Atlantic University, Hartmann, James X.
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Abstract/Description
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This project used a bioinformatics approach to identify the genetic differential expression of chronic lymphocytic leukemia (CLL) white blood cells as compared to normal white blood cells. Several public access databases and data mining tools were used to collect these data. The data collected was validated by independent bioinformatics databases and the methodology was supported by previously published "gene chip" differential expression data. This research identifies a pattern of...
Show moreThis project used a bioinformatics approach to identify the genetic differential expression of chronic lymphocytic leukemia (CLL) white blood cells as compared to normal white blood cells. Several public access databases and data mining tools were used to collect these data. The data collected was validated by independent bioinformatics databases and the methodology was supported by previously published "gene chip" differential expression data. This research identifies a pattern of differential gene expression specific to CLL white blood cells that can be used for the early diagnosis of CLL. The study also identifies the probable genetic origin for the low expression of tyrosine kinase and IgM immunoglobulin observed in CLL B-cells. Also presented are genes associated with chromosomal regions previously reported as deleted in a high percentage of CLL cases. These data can be used in further research and for the treatment of CLL.
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Date Issued
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2003
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PURL
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http://purl.flvc.org/fcla/dt/13024
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Subject Headings
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Lymphocytic leukemia, Gene expression, Bioinformatics, Leucocytes
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Format
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Document (PDF)
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Title
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RELATION OF SERUM CALCIUM AND FERRITIN LEVELS TO SIDEROLEUKOCYTE FORMATION IN EQUINE INFECTIOUS ANEMIA.
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Creator
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MCCORQUODALE, DONALD SINCLAIR, JR., Florida Atlantic University
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Abstract/Description
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It has been shown that sideroleukocyte formation in equine infectious anemia is related to the presence of detectable amounts of ferritin in the serum of the infected animal. The presence of ferritin has been associated with tissue breakdown as a result of the infectious process. A relatively simple agar diffusion technique has been reported which is of value in the screening of horses for the acute phase of equine infectious anemia. It has further been shown that infected leukocytes can be...
Show moreIt has been shown that sideroleukocyte formation in equine infectious anemia is related to the presence of detectable amounts of ferritin in the serum of the infected animal. The presence of ferritin has been associated with tissue breakdown as a result of the infectious process. A relatively simple agar diffusion technique has been reported which is of value in the screening of horses for the acute phase of equine infectious anemia. It has further been shown that infected leukocytes can be induced to form sideroleukocytes earlier and in greater number by the addition of ferritin or calcium. Non-infected horses can not be induced to form sideroleukocytes by the addition of only ferritin or calcium or infected sera. However, addition of both ferritin and calcium does cause induction of sideroleukocytes in normal leukocytes. Levels of serum calcium in infected horses were shown to be inversely proportional to both temperature of the animal and the formation of sideroleukocytes. The data indicated the important role of serum levels of ferritin and calcium to the mechanism of sideroleukocyte formation both in vivo and in vitro.
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Date Issued
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1971
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PURL
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http://purl.flvc.org/fcla/dt/13436
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Subject Headings
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Equine infectious anemia, Horses--Diseases, Ferritin, Leucocytes
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Format
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Document (PDF)
