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Title: Cytotoxin production by a marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor.
Creator: Armstrong, J. E., Janda, Kathleen E., Alvarado, B., Wright, Amy E.
Date Issued: 1991
PURL: http://purl.flvc.org/FCLA/DT/3333194
Subject Headings: Lyngbya, Cyanobacteria, Cytotoxin, Bioreactors
Format: Document (PDF)

Title: New cytotoxic acridine alkaloids from two deep water marine sponges of the family Pachastrellidae.
Creator: Gunawardana, G. P., Kohmoto, S., Burres, N. S., Harbor Branch Oceanographic Institute
Date Issued: 1989
PURL: http://purl.flvc.org/FCLA/DT/3353842
Subject Headings: Sponges, Acridines, Alkaloids, Cytotoxins
Format: Document (PDF)

Title: Cytotoxic peptides from marine sponges.
Creator: Gulavita, N. K., Wright, Amy E., McCarthy, Peter J., Pomponi, Shirley A., Longley, Ross E.
Date Issued: 1996
PURL: http://purl.flvc.org/fau/fd/FA00007341
Subject Headings: Sponges, Peptides, Cytotoxins, Stereochemistry
Format: Document (PDF)

Title: Isometachromin, a new cytotoxic sesquiterpenoid from a deep water sponge of the family Spongiidae.
Creator: McConnell, O. J., Longley, Ross E., Gunasekera, M., Harbor Branch Oceanographic Institute
Date Issued: 1992
PURL: http://purl.flvc.org/fau/fd/FA00007220
Subject Headings: Sponges, Sesquiterpenes, Cytotoxins, Porifera
Format: Document (PDF)

Title: Sponge-derived polyunsaturated C16 di- and tribromocarboxylic acids.
Creator: Ichiba, T.,, Scheuer, P. J., Kelly-Borges, M., Harbor Branch Oceanographic Institute
Date Issued: 1993
PURL: http://purl.flvc.org/FCLA/DT/3327211
Subject Headings: Sponges, Polyunsaturated fatty acids, Cytotoxin
Format: Document (PDF)

Title: Five new Discodermolide analogues from the marine sponge Discodermia species.
Creator: Gunasekera, Sarath P., Paul, Gopal K., Longley, Ross E., Isbrucker, Richard A., Pomponi, Shirley A.
Date Issued: 2002
PURL: http://purl.flvc.org/FCLA/DT/3319106
Subject Headings: Sponges --Research, Cytotoxin, Marine natural products, Polyketides
Format: Document (PDF)

Title: Acetylated analogues of the microtubule stabilizing agent Discodermolide: preparation and biological activity.
Creator: Gunasekera, Sarath P., Longley, Ross E., Isbrucker, Richard A., Harbor Branch Oceanographic Institute
Date Issued: 2001
PURL: http://purl.flvc.org/FCLA/DT/3319101
Subject Headings: Sponges --Research, Marine natural products, Cytotoxin, Acetylation
Format: Document (PDF)

Title: New cytotoxic peroxylactones from the marine sponge, Plakinastrella onkodes.
Creator: Horton, P. A., Longley, Ross E., Kelly-Borges, M., McConnell, O. J., Ballas, L. M., Harbor Branch Oceanographic Institute
Date Issued: 1994
PURL: http://purl.flvc.org/FCLA/DT/3319074
Subject Headings: Sponges --Research, Marine natural products, Cytotoxin
Format: Document (PDF)

Title: Two cytotoxic 3, 6-epidoxy fatty acids from an Indonesian sponge, Plakortis sp.
Creator: Ichiba, T., Scheuer, P. J., Kelly-Borges, M., Harbor Branch Oceanographic Institute
Date Issued: 1995
PURL: http://purl.flvc.org/FCLA/DT/3331902
Subject Headings: Sponges, Fatty acids, Cytotoxin, Marine natural products
Format: Document (PDF)

Title: Duryne, a new cytotoxic agent from the marine sponge Cribrochalina dura.
Creator: Wright, Amy E., McConnell, O. J., Kohmoto, S., Lui, M. S., Thompson, W., Snader, K. M.
Date Issued: 1987
PURL: http://purl.flvc.org/FCLA/DT/3353798
Subject Headings: Cytotoxin, Sponges, Marine natural products, Polyacetylenes
Format: Document (PDF)

Title: Synthesis of microcolin analogs using trimethylsilylated lactams.
Creator: Mattern, R.-H., Gunasekera, Sarath P., McConnell, O. J., Harbor Branch Oceanographic Institute
Date Issued: 1997
PURL: http://purl.flvc.org/FCLA/DT/3331922
Subject Headings: Oligopeptides, Immunosuppressive agents, Cytotoxin, Lactams, Peptides--Synthesis
Format: Document (PDF)

Title: More kapakahines from the marine sponge Cribrochalina olemda.
Creator: Nakao, Y., Kuo, J., Yoshida, W. Y., Kelly-Borges, M., Scheuer, P. J., Harbor Branch Oceanographic Institute
Date Issued: 2003
PURL: http://purl.flvc.org/FCLA/DT/3319108
Subject Headings: Sponges --Research, Cytotoxin, Nuclear magnetic resonance, Cyclic peptides
Format: Document (PDF)

Title: Puupehenone, a cytotoxic metabolite from a deep water marine sponge, Stronglyophora hartmani.
Creator: Kohmoto, S., McConnell, O. J., Wright, Amy E., Koehn, F. E., Thompson, W., Lui, M. S., Snader, K. M.
Date Issued: 1987
PURL: http://purl.flvc.org/FCLA/DT/3332938
Subject Headings: Sponges, Sesquiterpenes, Cytotoxin, Antineoplastic agents, Marine natural products
Format: Document (PDF)

Title: Brianthein V, a new cytotoxic and antiviral diterpene isolated from Briareum asbestinum.
Creator: Coval, S. J., Cross, S. S., Bernardinelli, G., Jefford, C. W., Harbor Branch Oceanographic Institute
Date Issued: 1988
PURL: http://purl.flvc.org/FCLA/DT/3332954
Subject Headings: Corals--Caribbean Sea, Gorgonacea, Diterpenes, Antiviral agents, Cytotoxin
Format: Document (PDF)

Title: Two new bioactive cyclic peroxides from the marine sponge Plakortis angulospiculatus.
Creator: Gunasekera, Sarath P., Gunasekera, M., Gunawardana, G. P., McCarthy, Peter J., Burres, N. S.
Date Issued: 1990
PURL: http://purl.flvc.org/FCLA/DT/3332965
Subject Headings: Sponges, Peroxides, Bioactive compounds, Antifungal agents, Cytotoxin, Marine metabolites
Format: Document (PDF)

Title: Makaluvamine G, a cytotoxic pigment from an Indonesian sponge Histodermella sp.
Creator: Carney, J. R., Scheuer, P. J., Kelly-Borges, M., Harbor Branch Oceanographic Institute
Date Issued: 1993
PURL: http://purl.flvc.org/FCLA/DT/3331874
Subject Headings: Sponges, Cytotoxin, Tryptamine--Derivatives--Synthesis, Tyramine, Antineoplastic agents
Format: Document (PDF)

Title: Antitumor activity and nucleic acid binding properties of Dercitin, a new acridinealkaloid isolated from a marine dercitus species sponge.
Creator: Burres, N. S., Sazesh, S., Gunawardana, G. P., Clement, J. J., Harbor Branch Oceanographic Institute
Date Issued: 1989
PURL: http://purl.flvc.org/fau/fd/FA00007199
Subject Headings: Alkaloids, Acridines, Sponges, Antineoplastic agents, Cytotoxins, Marine natural products
Format: Document (PDF)

Title: New manzamine alkaloids from a sponge of the genus xestospongia.
Creator: Ichiba, T., Sakai, R., Kohmoto, S., Saucy, G., Higa, T., Harbor Branch Oceanographic Institute
Date Issued: 1988
PURL: http://purl.flvc.org/FCLA/DT/3353822
Subject Headings: Alkaloids, Indole Alkaloids, Sponges, Cytotoxin, Carbazoles, Chemical structure
Format: Document (PDF)

Title: Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol.
Creator: Haar, E., Kowalski, R. J., Hamel, E., Lin, C. M., Longley, Ross E., Gunasekera, Sarath P., Rosenkranz, H. S., Day, B. W., Harbor Branch Oceanographic Institute
Date Issued: 1996
PURL: http://purl.flvc.org/FCLA/DT/3319092
Subject Headings: Marine natural products, Antimitotic agents, Taxol, Cytotoxin, Marine toxins
Format: Document (PDF)

Title: The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells.
Creator: Kowalski, R. J., Giannakakou, P., Gunasekera, Sarath P., Longley, Ross E., Day, B. W., Hamel, E., Harbor Branch Oceanographic Institute
Date Issued: 1997
PURL: http://purl.flvc.org/fau/fd/FA00007052
Subject Headings: Marine natural products, Cytotoxins, Tubulin Modulators, Paclitaxel, Lactones, Sponges
Format: Document (PDF)

Cytotoxin (20)	+ -
Sponges (13)	+ -
Marine natural products (12)	+ -
Cytotoxins (7)	+ -
Antineoplastic agents (6)	+ -

Sponges --Research (5)	+ -
Alkaloids (3)	+ -
Acridines (2)	+ -
Carbazoles (2)	+ -
Chemical structure (2)	+ -
Gorgonacea (2)	+ -
Immunosuppressive agents (2)	+ -
Lactones (2)	+ -
Lyngbya (2)	+ -
Marine metabolites (2)	+ -
Marine toxins (2)	+ -
Oligopeptides (2)	+ -
Sesquiterpenes (2)	+ -
X-ray crystallography (2)	+ -
Acetylation (1)	+ -
Anthraquinones (1)	+ -
Antifungal agents (1)	+ -
Antimicrobial agents (1)	+ -
Antimitotic agents (1)	+ -
Antitumor antibiotics (1)	+ -
Antiviral agents (1)	+ -
Ascidians (1)	+ -
Bioactive compounds (1)	+ -
Biologically active compounds (1)	+ -
Bioreactors (1)	+ -

Harbor Branch Oceanographic Institute (18)	+ -
Longley, Ross E. (10)	+ -
Gunasekera, Sarath P. (9)	+ -
Wright, Amy E. (8)	+ -
McConnell, O. J. (7)	+ -

Kelly-Borges, M. (6)	+ -
Kohmoto, S. (5)	+ -
Scheuer, P. J. (5)	+ -
Burres, N. S. (4)	+ -
Gunasekera, M. (3)	+ -
Gunawardana, G. P. (3)	+ -
Ichiba, T. (3)	+ -
McCarthy, Peter J. (3)	+ -
Pomponi, Shirley A. (3)	+ -
Day, B. W. (2)	+ -
Hamel, E. (2)	+ -
Horton, P. A. (2)	+ -
Isbrucker, Richard A. (2)	+ -
Koehn, F. E. (2)	+ -
Kowalski, R. J. (2)	+ -
Lui, M. S. (2)	+ -
Mattern, R.-H. (2)	+ -
Schulte, G. K. (2)	+ -
Snader, K. M. (2)	+ -
Thompson, W. (2)	+ -
Alvarado, B. (1)	+ -
Armstrong, J. E. (1)	+ -
Ballas, L. M. (1)	+ -
Bernardinelli, G. (1)	+ -
Biabani, Misbah F. (1)	+ -

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