Current Search:  Biological oceanography (x)

View All Items

  • CSV Spreadsheet
(1 - 4 of 4)
In memoriam: John Hood Ryther 1922-2006
Title
In memoriam: John Hood Ryther 1922-2006.
Creator
Mann, Roger, Yentsch, Charles S., Lapointe, Brian E.
Date Issued
2007
PURL
http://purl.flvc.org/FCLA/DT/3174063
Subject Headings
Plankton, Marine plankton, Marine biology, Biological oceanography
Format
Document (PDF)
Thin layers of bioluminescent copepods found at density discontinuities in the water column
Title
Thin layers of bioluminescent copepods found at density discontinuities in the water column.
Creator
Widder, Edith A., Johnsen, Sonke, Bernstein, S. A., Case, J. F., Neilson, D. J., Harbor Branch Oceanographic Institute
Date Issued
1999
PURL
http://purl.flvc.org/FCLA/DT/2795600
Subject Headings
Biological oceanography, Bioluminescence, Marine animals --Food
Format
Document (PDF)
Bioactive terpene production associated with Caribbean gorgonians from the genera Pseudopterogorgia and Eunicea: Discovery of a sustainable production method
Title
Bioactive terpene production associated with Caribbean gorgonians from the genera Pseudopterogorgia and Eunicea: Discovery of a sustainable production method.
Creator
Newberger, Nealie C., Florida Atlantic University, Charles E. Schmidt College of Science, Department of Chemistry and Biochemistry
Abstract/Description
Research directed toward renewable, non-destructive sources of bioactive marine derived compounds, is becoming more important everyday. Marine soft corals known as sea whips are a prolific source of such biologically active compounds. One particular organism, Eunicea fusca, possesses diterpene arabinose glycosides with potent antiinflammatory activity that rival the industry standard indomethicin. Fuscocide B is known to inhibit phorbol myristate acetate (PMA)-induced ear edema in murine...
Show moreResearch directed toward renewable, non-destructive sources of bioactive marine derived compounds, is becoming more important everyday. Marine soft corals known as sea whips are a prolific source of such biologically active compounds. One particular organism, Eunicea fusca, possesses diterpene arabinose glycosides with potent antiinflammatory activity that rival the industry standard indomethicin. Fuscocide B is known to inhibit phorbol myristate acetate (PMA)-induced ear edema in murine models, is a minor secondary metabolite and it is therefore difficult to acquire in large quantities. Alternatively, fuscol and eunicol, are known to have similar antiinflammatory activity and are major secondary metabolites which are structurally similar to fuscocide B and are also produced by E. fusca. We have found that fuscol and eunicol can be extracted from the holobiont, and Symbiodinium (Symbiodinium sp.) cells isolated from E. fusca. Similarly, diterpene glycosides, known as pseudopterosins, have been isolated from the the holobiont, and purified Symbiodinium of Pseudopterogorgia elisabethae. Pseudopterosins are also known to possess anti-inflammatory and analgesic properties superior to that of existing drugs. Since many chemically unique metabolites demonstrating bioactive properties have been introduced into pre-clinical and clinical trials I-III5 and the supply issue has been duly highlighted, it has become advantageous to determine the source of these compounds in each of the above mentioned species and determine if a renewable, non-destructive source can be maintained. Data has been presented suggesting that the actual source of the pseudopterosins is not the coral, but actually the dinoflagellate symbiont associated with Pseudopterogorgia elisabethae. Therefore, we have examined cryopreservation of the dinoflagellate symbionts, induction of terpene biosynthesis in the dinoflagellate symbionts, as well as various cell culture techniques in order to better understand the ecological role of terpene biosynthesis in the symbionts and the host corals. The data obtained in the following studies reveals a bacterial source for the production of bioactive secondary metabolites from Eunicea fusca and lends support to a possible bacterial producing trend in gorgonians.
Show less
Date Issued
2006
PURL
http://purl.flvc.org/fcla/dt/12224
Subject Headings
Biology, Oceanography, Chemistry, Biochemistry, Chemistry, Organic
Format
Document (PDF)
In situ observations on three species of largefinned deep-sea squids
Title
In situ observations on three species of largefinned deep-sea squids.
Creator
Vecchione, M., Roper, C. F. E., Widder, Edith A., Frank, Tamara M., Harbor Branch Oceanographic Institute
Date Issued
2002
PURL
http://purl.flvc.org/FCLA/DT/3171653
Subject Headings
Squids, Giant squids, Oceanography --Observations, Oceanographic submersibles, Marine biology
Format
Document (PDF)