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Florida Atlantic University 2018 3MT® Three Minute Thesis Championship - Sandhya Sharma
Title
Florida Atlantic University 2018 3MT® Three Minute Thesis Championship - Sandhya Sharma.
Creator
Sharma, Sandhya, Florida Atlantic University
Abstract/Description
The 3MT® competition celebrates the exciting research conducted by graduate students. Developed by The University of Queensland (UQ), the exercise cultivates students’ academic, presentation, and research communication skills. The competition supports their capacity to effectively explain their research in three minutes, in language appropriate to a non-specialist audience. The first 3MT® competition was held at the University of Queensland in 2008 with 160 students competing. In 2009 and...
Show moreThe 3MT® competition celebrates the exciting research conducted by graduate students. Developed by The University of Queensland (UQ), the exercise cultivates students’ academic, presentation, and research communication skills. The competition supports their capacity to effectively explain their research in three minutes, in language appropriate to a non-specialist audience. The first 3MT® competition was held at the University of Queensland in 2008 with 160 students competing. In 2009 and 2010 the 3MT® competition was promoted to other Australian and New Zealand universities and enthusiasm for the concept grew. Since 2011, the popularity of the competition has increased and 3MT® competitions are now held in over 170 universities across more than 18 countries worldwide.
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Date Issued
2018
PURL
http://purl.flvc.org/fau/fd/FA00007565
Subject Headings
College students --Research --United States.
Format
Video file
Cytogenetic of chromosomal synteny evaluation: bioinformatic applications towards screening of chromosomal aberrations/ genetic disorder
Title
Cytogenetic of chromosomal synteny evaluation: bioinformatic applications towards screening of chromosomal aberrations/ genetic disorder.
Creator
Sharma, Sandhya, Neelakanta, Perambur S., Florida Atlantic University, College of Engineering and Computer Science, Department of Computer and Electrical Engineering and Computer Science
Abstract/Description
The research efforts refer to tracking homologus loci in the chromosomes of a pair of a species. The purpose is to infer the extent of maximum syntenic correlation when an exhaustive set of orthologs of the species are searched. Relevant bioinformatic analyses use comparative mapping of conserved synteny via Oxford grid. In medical diagnostic efforts, deducing such synteny correlation can help screening chromosomal aberration in genetic disorder pathology. Objectively, the present study...
Show moreThe research efforts refer to tracking homologus loci in the chromosomes of a pair of a species. The purpose is to infer the extent of maximum syntenic correlation when an exhaustive set of orthologs of the species are searched. Relevant bioinformatic analyses use comparative mapping of conserved synteny via Oxford grid. In medical diagnostic efforts, deducing such synteny correlation can help screening chromosomal aberration in genetic disorder pathology. Objectively, the present study addresses: (i) Cytogenetic framework of syntenic correlation and, (ii) applying information-theoretics to determine entropy-dictated synteny across an exhaustive set of orthologs of the test pairs of species.
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Date Issued
2014
PURL
http://purl.flvc.org/fau/fd/FA00004331, http://purl.flvc.org/fau/fd/FA00004331
Subject Headings
Cytogenetics, Genetic screening, Human chromosome abnormalities, Medical genetics, Molecular biology, Molecular diagnosis, Molecular genetics, Mutation (Biology)
Format
Document (PDF)
DEVELOPMENT OF MICROFLUIDIC PLATFORMS FOR INFECTIOUS DISEASES DIAGNOSIS AND SPERM CELL SORTING
Title
DEVELOPMENT OF MICROFLUIDIC PLATFORMS FOR INFECTIOUS DISEASES DIAGNOSIS AND SPERM CELL SORTING.
Creator
Sharma, Sandhya, Asghar, Waseem, Florida Atlantic University, Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
Abstract/Description
In recent years, point-of-care (POC) microfluidic platforms have transformed the healthcare landscape as they offer rapid, low-cost, and easy operational benefits. POC diagnostics play an important role in expediting the testing process in resource-constrained areas. These platforms have become a powerful tool as they offer comparable results with gold-standard methods. The gold standard methods require sophisticated lab locations and expensive equipment, to process the samples which is a...
Show moreIn recent years, point-of-care (POC) microfluidic platforms have transformed the healthcare landscape as they offer rapid, low-cost, and easy operational benefits. POC diagnostics play an important role in expediting the testing process in resource-constrained areas. These platforms have become a powerful tool as they offer comparable results with gold-standard methods. The gold standard methods require sophisticated lab locations and expensive equipment, to process the samples which is a significant challenge particularly for people living in low-income countries. To address these limitations, herein, in my dissertation, I have developed POC microfluidic platforms that can be operated outside the laboratory using lesser equipment statistically hence reducing the testing cost and time. The developed POC chips are used for infectious diseases diagnosis for viruses such as Zika, Hepatitis C Virus (HCV), and severe acute respiratory syndrome coronavirus 2 (SARSCoV-2). The entire virus detection process was executed inside a uniquely designed, inexpensive, disposable self-driven microfluidic chip with high sensitivity and specificity. In addition to this, I have also developed a microfluidic platform for functional sperm cell sorting from raw semen samples. The microfluidic chip offers a platform where the sperm cells experience different shear stress in different parts of the chip that facilitates isolation of competent sperm cells without impacting their integrity. Simultaneously, it also allows effortless collection of sorted sperm cells from the collection chamber which holds clinical significance. All things considered, the developed devices are inexpensive, disposable, easy-to-use, and rapid that provide results within one hour.
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Date Issued
2022
PURL
http://purl.flvc.org/fau/fd/FA00013906
Subject Headings
Microfluidics, Point-of-care testing, Communicable diseases—Diagnosis
Format
Document (PDF)