Current Search: Mock, Thomas J. (x)
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Title
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Pentraxin 3 Reactivity to Acute Exercise in Obese Individuals.
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Creator
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Maharaj, Arun, Urtula, Alyssa M., Slusher, Aaron L., Mock, J. Thomas, Fisher, Craig B., Huang, Chun-Jung
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Abstract/Description
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Pentraxin 3 (PTX3) has been demonstrated as a vital biomarker for chronic inflammatory diseases. Decreased plasma PTX3 has been observed in obese populations. However, no studies have examined the impact of obesity on PTX3 reactivity to exercise. Therefore, our study sought to investigate PTX3 plasma response to maximal exercise in obese and normal-weight subjects, and its relationship with insulin sensitivity. Twenty-one subjects (9 obese and 12 normal-weight) were recruited. Plasma PTX3,...
Show morePentraxin 3 (PTX3) has been demonstrated as a vital biomarker for chronic inflammatory diseases. Decreased plasma PTX3 has been observed in obese populations. However, no studies have examined the impact of obesity on PTX3 reactivity to exercise. Therefore, our study sought to investigate PTX3 plasma response to maximal exercise in obese and normal-weight subjects, and its relationship with insulin sensitivity. Twenty-one subjects (9 obese and 12 normal-weight) were recruited. Plasma PTX3, insulin, and glucose levels were measured before and following exercise. While our results showed lower resting PTX3 levels in obese subjects, exercise elicited similar elevations in PTX3 and insulin sensitivity in both groups. Furthermore, PTX3 area-under-curve (AUC) was correlated with glucose AUC, even when controlled for body mass index and fitness level. These findings suggest that glucose may potentially regulate PTX3 response to exercise. Further investigation is needed to verify the impact of substrate utilization on exercise-induced PTX3 elevation.
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Date Issued
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2014
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PURL
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http://purl.flvc.org/fau/fd/FA0005028
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Subject Headings
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College students --Research --United States.
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Format
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Document (PDF)
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Title
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The effect of acute moderate-intensity continuous and high intensity interval exercise on serum brain-derived neurotrophic factor in recreationally trained males.
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Creator
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Mock, Thomas J., Whitehurst, Michael, Florida Atlantic University, College of Education, Department of Exercise Science and Health Promotion
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Abstract/Description
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BDNF is a neurotrophin that enhances neural health and is increased by exercise. PURPOSE: To compare moderate continuous (MCE) and high-intensity interval exercise (HIE) effects on serum BDNF levels, and examine the relationship between BDNF and lactate. METHODS: Seven males completed a VO2peak test and two protocols on separate days, (MCE) 28 min at 60% Workrate max (WRmax) and (HIE) 28 min of intervals at 90%WRmax (10- 1 min intervals separated by 2 min of rest). Serum BDNF and lactate were...
Show moreBDNF is a neurotrophin that enhances neural health and is increased by exercise. PURPOSE: To compare moderate continuous (MCE) and high-intensity interval exercise (HIE) effects on serum BDNF levels, and examine the relationship between BDNF and lactate. METHODS: Seven males completed a VO2peak test and two protocols on separate days, (MCE) 28 min at 60% Workrate max (WRmax) and (HIE) 28 min of intervals at 90%WRmax (10- 1 min intervals separated by 2 min of rest). Serum BDNF and lactate were determined prior, during, and following both protocols. RESULTS: BDNF levels (pg/mL) increased from baseline during HIE and MCE (p<.05). The BDNF response to HIE correlated with lactate for area under the curve (AUC) (r=0.901; P<0.05). CONCLUSION: HIE is an effective alternative to MCE at increasing BDNF. Additionally, lactate may act as a measure of intensity or a mediator of the BDNF response to exercise.
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Date Issued
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2014
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PURL
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http://purl.flvc.org/fau/fd/FA00004219, http://purl.flvc.org/fau/fd/FA00004219
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Subject Headings
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Biochemical markers., Neurons--Physiology., Cell aging--Physiology., Neurotrophic function., Metabolic syndrome--Pathophysiology.
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Format
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Document (PDF)
