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(1 - 4 of 4)
- Title
- The Impact of Obesity on Plasma Calprotectin in Response to Acute Aerobic Exercise.
- Creator
- Fico, Brandon G., Slusher, Aaron L., Whitehurst, Michael, Maharaj, Arun, Huang, Chun-Jung, College of Education
- Abstract/Description
-
The secular issue of obesity has been linked to increased inflammatory mediators, such as calprotectin (S100A8/A9). This study examined the effect of acute aerobic exercise on plasma calprotectin response in obese and normal-weight subjects and its relationship with inflammatory cytokine (IL-6). All subjects (11 obese and 10 normal-weight) performed 30 minutes of treadmill exercise at 75% maximal oxygen consumption (VO2max). Blood samples were collected prior to, immediately following...
Show moreThe secular issue of obesity has been linked to increased inflammatory mediators, such as calprotectin (S100A8/A9). This study examined the effect of acute aerobic exercise on plasma calprotectin response in obese and normal-weight subjects and its relationship with inflammatory cytokine (IL-6). All subjects (11 obese and 10 normal-weight) performed 30 minutes of treadmill exercise at 75% maximal oxygen consumption (VO2max). Blood samples were collected prior to, immediately following exercise, and one hour after exercise. Our results showed higher baseline levels of calprotectin in obese subjects than normal-weight subjects. While acute aerobic exercise increased an elevation in calprotectin and IL-6, no difference was found between two groups. Furthermore, a positive relationship was observed between calprotectin area-under-the curve “with respect to increase” (AUCi) and IL-6 AUCi, even after controlling for cardiorespiratory fitness (VO2max). Our results support previous finding that IL-6 may potentially regulate calprotectin expression in skeletal muscle during exercise.
Show less - Date Issued
- 2015
- PURL
- http://purl.flvc.org/fau/fd/FA00005187
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Comparing the Effects of CEEE versus HIIT Exercise on Cardiac Damage in Cyprinus carpio.
- Creator
- Jessica L. Halle, Gabriel S. Pena, Arun Maharaj, Michael Whitehurst
- Date Issued
- 2017
- PURL
- http://purl.flvc.org/fau/fd/FAU_SR00000012
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Pentraxin 3 Reactivity to Acute Exercise in Obese Individuals.
- Creator
- Maharaj, Arun, Urtula, Alyssa M., Slusher, Aaron L., Mock, J. Thomas, Fisher, Craig B., Huang, Chun-Jung
- Abstract/Description
-
Pentraxin 3 (PTX3) has been demonstrated as a vital biomarker for chronic inflammatory diseases. Decreased plasma PTX3 has been observed in obese populations. However, no studies have examined the impact of obesity on PTX3 reactivity to exercise. Therefore, our study sought to investigate PTX3 plasma response to maximal exercise in obese and normal-weight subjects, and its relationship with insulin sensitivity. Twenty-one subjects (9 obese and 12 normal-weight) were recruited. Plasma PTX3,...
Show morePentraxin 3 (PTX3) has been demonstrated as a vital biomarker for chronic inflammatory diseases. Decreased plasma PTX3 has been observed in obese populations. However, no studies have examined the impact of obesity on PTX3 reactivity to exercise. Therefore, our study sought to investigate PTX3 plasma response to maximal exercise in obese and normal-weight subjects, and its relationship with insulin sensitivity. Twenty-one subjects (9 obese and 12 normal-weight) were recruited. Plasma PTX3, insulin, and glucose levels were measured before and following exercise. While our results showed lower resting PTX3 levels in obese subjects, exercise elicited similar elevations in PTX3 and insulin sensitivity in both groups. Furthermore, PTX3 area-under-curve (AUC) was correlated with glucose AUC, even when controlled for body mass index and fitness level. These findings suggest that glucose may potentially regulate PTX3 response to exercise. Further investigation is needed to verify the impact of substrate utilization on exercise-induced PTX3 elevation.
Show less - Date Issued
- 2014
- PURL
- http://purl.flvc.org/fau/fd/FA0005028
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- The Effect of Maximal Aerobic Exercise on Plasma BDNF and BDNF Expression in PBMCs in Obese and Non-Obese Individuals.
- Creator
- Maharaj, Arun, Whitehurst, Michael, Florida Atlantic University, College of Education, Department of Exercise Science and Health Promotion
- Abstract/Description
-
The purpose of this study was to determine if maximal aerobic exercise promotes BDNF expression in obese individuals. Plasma levels and the expression of BDNF in PBMCs were examined. 22 participants (10 obese, 12 non-obese) completed a V02max treadmill test and blood was obtained pre, post, and 1 and 2 hours into exercise recovery. Plasma and PBMCs were isolated and analyzed for BDNF via ELISA and Western blot techniques. A significant effect for time was observed for plasma BDNF (P=
Show moreThe purpose of this study was to determine if maximal aerobic exercise promotes BDNF expression in obese individuals. Plasma levels and the expression of BDNF in PBMCs were examined. 22 participants (10 obese, 12 non-obese) completed a V02max treadmill test and blood was obtained pre, post, and 1 and 2 hours into exercise recovery. Plasma and PBMCs were isolated and analyzed for BDNF via ELISA and Western blot techniques. A significant effect for time was observed for plasma BDNF (P= <0.00 1 ). Additionally, A significant group-by-time interaction was found from pre-to-RIH for BDNF expression in PBMCs (P= 0.046). Further, significant correlations were found between BMI and waist circumference (r= .91, P< 0.001), WHR (r= .51, P= 0.002) and Pre-to-RlH ratio (r=0.58, P=0.008). Young obese subject's BDNF response to maximal exercise was consistent with previous studies. Post-exercise BDNF expressed in PBMCs were significantly higher than rest suggesting immunological-neuroprotective interactions in the CNS.
Show less - Date Issued
- 2016
- PURL
- http://purl.flvc.org/fau/fd/FA00004664, http://purl.flvc.org/fau/fd/FA00004664
- Subject Headings
- Biochemical markers, Blood lipoproteins, Blood plasma -- Physiology, Exercise -- Physiological aspects, Obesity -- Exercise therapy
- Format
- Document (PDF)
