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Motion challenges in high dose rate (HDR) brachytherapy
Title
Motion challenges in high dose rate (HDR) brachytherapy.
Creator
Curley, Casey Michael, Pella, Silvia, Leventouri, Theodora, Graduate College
Date Issued
2013-04-12
PURL
http://purl.flvc.org/fcla/dt/3361287
Subject Headings
Brachytherapy, Leipzig, Immobilization
Format
Document (PDF)
Investigation of Dose Variation with Minor Displacement in High Dose Radiation Brachytherapy
Title
Investigation of Dose Variation with Minor Displacement in High Dose Radiation Brachytherapy.
Creator
Hyvärinen, Mikko, Curley, Casey Michael, Long, Samanthia, Graduate College, Herrera, Ramses, Dumitru, Nicolae, Pella, Silvia
Abstract/Description
High dose rate HDR brachytherapy dose distribution is highly localized and has a very sharp dose fall-off. Thus one of the most important part of the treatment is the localization and immobilization of the applicator from the implantation to the setup verification to the treatment delivery. The smallest motions of the patient can induce a small rotation, tilt, or translational movement of the applicator that can convert into miss of a significant part of the tumor or to over irradiating a...
Show moreHigh dose rate HDR brachytherapy dose distribution is highly localized and has a very sharp dose fall-off. Thus one of the most important part of the treatment is the localization and immobilization of the applicator from the implantation to the setup verification to the treatment delivery. The smallest motions of the patient can induce a small rotation, tilt, or translational movement of the applicator that can convert into miss of a significant part of the tumor or to over irradiating a nearby critical organ. The purpose of this study is to revise most of the HDR types of treatments with their applicators and their localization challenges. Since every millimeter of misplacement counts the study will look into the necessity of increasing the immobilization for several types of applicators. This study data indicates that an improvement of the immobilization devices for HDR is absolutely necessary. Better applicator fixation devices are required too. Developing new immobilization devices for all the applicators is recommended.
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Date Issued
2014
PURL
http://purl.flvc.org/fau/fd/FA00005824
Format
Document (PDF)
A dosimetric study of a heterogeneous phantom for lung stereotactic body radiation therapy comparing Monte Carlo and pencil beam calculations to dose distributions measured with a 2-d diode array
Title
A dosimetric study of a heterogeneous phantom for lung stereotactic body radiation therapy comparing Monte Carlo and pencil beam calculations to dose distributions measured with a 2-d diode array.
Creator
Curley, Casey Michael, Ouhib, Zoubir, Florida Atlantic University, Charles E. Schmidt College of Science, Department of Physics
Abstract/Description
Monte Carlo (MC) and Pencil Beam (PB) calculations are compared to their measured planar dose distributions using a 2-D diode array for lung Stereotactic Body Radiation Therapy (SBRT). The planar dose distributions were studied for two different phantom types: an in-house heterogeneous phantom and a homogeneous phantom. The motivation is to mimic the human anatomy during a lung SBRT treatment and incorporate heterogeneities into the pre-treatment Quality Assurance process, where measured and...
Show moreMonte Carlo (MC) and Pencil Beam (PB) calculations are compared to their measured planar dose distributions using a 2-D diode array for lung Stereotactic Body Radiation Therapy (SBRT). The planar dose distributions were studied for two different phantom types: an in-house heterogeneous phantom and a homogeneous phantom. The motivation is to mimic the human anatomy during a lung SBRT treatment and incorporate heterogeneities into the pre-treatment Quality Assurance process, where measured and calculated planar dose distributions are compared before the radiation treatment. Individual and combined field dosimetry has been performed for both fixed gantry angle (anterior to posterior) and planned gantry angle delivery. A gamma analysis has been performed for all beam arrangements. The measurements were obtained using the 2-D diode array MapCHECK 2™.
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Date Issued
2015
PURL
http://purl.flvc.org/fau/fd/FA00004360
Subject Headings
Cancer -- Radiotherapy, Drug development -- Computer simulation, Image guided radiation therapy, Ion bombardment, Lung cancer -- Treatment, Medical physics, Monte Carlo method, Proton beams
Format
Document (PDF)
Phantom Study Incorporating A Diode Array Into The Treatment Planning System For Patient-Specific Quality Assurance
Title
Phantom Study Incorporating A Diode Array Into The Treatment Planning System For Patient-Specific Quality Assurance.
Creator
Curley, Casey Michael, Leventouri, Theodora, Ouhib, Zoubir, Florida Atlantic University, Charles E. Schmidt College of Science, Department of Physics
Abstract/Description
The purpose of this research is to accurately match the calculation environment, i.e. the treatment planning system (TPS) with the measurement environment (using a 2-D diode array) for lung Stereotactic Body Radiation Therapy (SBRT) patient-specific quality assurance (QA). Furthermore, a new phantom was studied in which the 2-D array and heterogeneities were incorporated into the patient-specific QA process for lung SBRT. Dual source dual energy computerized tomography (DSCT) and single...
Show moreThe purpose of this research is to accurately match the calculation environment, i.e. the treatment planning system (TPS) with the measurement environment (using a 2-D diode array) for lung Stereotactic Body Radiation Therapy (SBRT) patient-specific quality assurance (QA). Furthermore, a new phantom was studied in which the 2-D array and heterogeneities were incorporated into the patient-specific QA process for lung SBRT. Dual source dual energy computerized tomography (DSCT) and single energy computerized tomography (SECT) were used to model phantoms incorporating a 2-D diode array into the TPS. A water-equivalent and a heterogeneous phantom (simulating the thoracic region of a patient) were studied. Monte Carlo and pencil beam dose distributions were compared to the measured distributions. Composite and individual fields were analyzed for normally incident and planned gantry angle deliveries. The distributions were compared using γ-analysis for criteria 3% 3mm, 2% 2mm, and 1% 1mm. The Monte Carlo calculations for the DSCT modeled phantoms (incorporating the array) showed an increase in the passing percentage magnitude for 46.4 % of the fields at 3% 3mm, 85.7% at 2% 2mm, and 92.9% at 1% 1mm. The Monte Carlo calculations gave no agreement for the same γ-analysis criteria using the SECT. Pencil beam calculations resulted in lower passing percentages when the diode array was incorporated in the TPS. The DSCT modeled phantoms (incorporating the array) exhibited decrease in the passing percentage magnitude for 85.7% of the fields at 3% 3mm, 82.1% at 2% 2mm, and 71.4% at 1% 1mm. In SECT modeled phantoms (incorporating the array), a decrease in passing percentage magnitude were found for 92.9% of the fields at 3% 3mm, 89.3% at 2% 2mm, and 82.1% at 1% 1mm. In conclusion, this study demonstrates that including the diode array in the TPS results in increased passing percentages when using a DSCT system with a Monte Carlo algorithm for patient-specific lung SBRT QA. Furthermore, as recommended by task groups (e.g. TG 65, TG 101, TG 244) of the American Association of Physicists in Medicine (AAPM), pencil beam algorithms should be avoided in the presence of heterogeneous materials, including a diode array.
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Date Issued
2016
PURL
http://purl.flvc.org/fau/fd/FA00004744, http://purl.flvc.org/fau/fd/FA00004744
Subject Headings
Cancer--Radiotherapy., Lungs--Cancer--Treatment., Monte Carlo method., Proton beams., Image-guided radiation therapy., Ion bombardment., Medical physics.
Format
Document (PDF)