View All Items

Title: Biochemical and biosynthetic optimization of bryostatin 1 in Bugula neritina.
Creator: Vicchiarelli, Richard, Florida Atlantic University, Kerr, Russell G.
Abstract/Description: Bryostatin 1 is a macrocyclic lactone isolated from the marine bryozoan Bugula neritina. It is currently in clinical trials at the National Cancer Institute as a promising new antileukemic agent. Bryostatin 1 is found in Bugula neritina in poor yields (10^-4% dry weight). The focus of this research was to develop the biochemical and biosynthetic techniques that could be utilized to optimize the production of bryostatin 1 in Bugula neritina through aquaculture. To that end, the basic...
Show moreBryostatin 1 is a macrocyclic lactone isolated from the marine bryozoan Bugula neritina. It is currently in clinical trials at the National Cancer Institute as a promising new antileukemic agent. Bryostatin 1 is found in Bugula neritina in poor yields (10^-4% dry weight). The focus of this research was to develop the biochemical and biosynthetic techniques that could be utilized to optimize the production of bryostatin 1 in Bugula neritina through aquaculture. To that end, the basic biosynthetic pathway to bryostatin 1 in the marine bryozoan was evaluated by using radiolabeled precursors. Techniques for the incorporation of these precursors were also developed. Other experiments involved an analysis of the composition of a specific population of Bugula neritina in terms of its bryostatin and lipid content. A determination of which lipids are produced de novo and which are exogenous was also undertaken.
Show less
Date Issued: 1993
PURL: http://purl.flvc.org/fcla/dt/14931
Subject Headings: Bryozoa, Aquaculture--Research
Format: Document (PDF)

Title: Purification and Characterization of Tellurium.
Creator: Edwards, Richard Victor Jr., Blakemore, John S., Florida Atlantic University
Abstract/Description: For further investigations into the many unknown properties of tellurium, single crystals of high purity and perfection are needed. This thesis contains a report of the purification of tellurium by means of normal freezing, vacuum distillation, and zone refining. The purified material has been grown into single crystals by the Czochralski method. Crystals were also grown following each of the purification processes. All of the purification processes were carried out in a forming gas...
Show moreFor further investigations into the many unknown properties of tellurium, single crystals of high purity and perfection are needed. This thesis contains a report of the purification of tellurium by means of normal freezing, vacuum distillation, and zone refining. The purified material has been grown into single crystals by the Czochralski method. Crystals were also grown following each of the purification processes. All of the purification processes were carried out in a forming gas atmosphere (85% nitrogen, 15% hydrogen). Samples cleaved at 77K and whole crystals were subjected to measurements of conductivity, Hall coefficient, and minority carrier lifetime as a function of temperature over the range 77 to 300K. The conductivity and Hall coefficient measurements serve to classify the crystals as to chemical purity, while the minority carrier lifetime measurements give an indication of the perfection of the crystalline structure. A complete description of the processes used and the apparatus that was constructed is included along with a discussion of the results.
Show less
Date Issued: 1968
PURL: http://purl.flvc.org/fau/fd/FA00000750
Subject Headings: Tellurium, Tellurium--Purification
Format: Document (PDF)

Title: ENVIRONMENTAL CONTROL: ITS COSTS AND RELATIONSHIP BETWEEN BUSINESS AND SOCIETY.
Creator: PITTMAN, RICHARD K., Florida Atlantic University, Franklin, Charles B. Jr., College of Business, Department of Management
Abstract/Description: This paper was intended as an exploratory look into the problems of environmental control with special attention given to its costs and effects on business and society. Since I had no concrete bypothesis with which to begin the paper, I chose to use exploratory research. Pollution is current, however, and I felt that there was a particular problem concerning pollution and how much it will cost. After a survey of the experts in the field and their proposals, I found some very definite trends....
Show moreThis paper was intended as an exploratory look into the problems of environmental control with special attention given to its costs and effects on business and society. Since I had no concrete bypothesis with which to begin the paper, I chose to use exploratory research. Pollution is current, however, and I felt that there was a particular problem concerning pollution and how much it will cost. After a survey of the experts in the field and their proposals, I found some very definite trends. I found the general feeling to be that there is a growing conflict concerning just who is going to pay for pollu~ion control. Whoever pays for the costs, I found that the present market structure does not properly account for the costs of pollution control. These findings led me to the conclusion that pollution control is more of a problem than I suspected and that it deserves more complete analysis as to possible solutions.
Show less
Date Issued: 1973
PURL: http://purl.flvc.org/fcla/dt/13544
Subject Headings: Business Administration, General
Format: Document (PDF)

Title: Ecology of the barracudinas (Aulopiformes: Paralepididae), a ubiquitous but understudied mesopelagic predatory fish family, in the Gulf of Mexico.
Creator: Jones, Richard, Moore, Jon, Florida Atlantic University, Charles E. Schmidt College of Science, Center for Environmental Studies
Abstract/Description: The Deepwater Horizon oil spill in 2010 prompted an enormous survey effort to assess the under-studied, deep-ocean ecosystems of the Gulf of Mexico. The resulting samples and datasets afforded a unique opportunity to study the ecology of a poorly known group of mesopelagic fishes, the barracudinas (Aulopiformes: Paralepididae). Here we address several important data gaps regarding the ecology of the Paralepididae. Our results indicate that a majority of barracudina species are efficient at...
Show moreThe Deepwater Horizon oil spill in 2010 prompted an enormous survey effort to assess the under-studied, deep-ocean ecosystems of the Gulf of Mexico. The resulting samples and datasets afforded a unique opportunity to study the ecology of a poorly known group of mesopelagic fishes, the barracudinas (Aulopiformes: Paralepididae). Here we address several important data gaps regarding the ecology of the Paralepididae. Our results indicate that a majority of barracudina species are efficient at avoiding research-sized nets, suggesting that their overall abundance has been historically underestimated. Notable differences in vertical distribution, seasonal abundances of sizes classes, and diets were observed among the three major sub-groups of the family, with potential implications to ecosystem-based management of deep-pelagic fisheries. This thesis is dedicated to all the fish, squids, and shrimps that gave their lives to make these data and to those that endured the hardship of the Deepwater Horizon oil spill.
Show less
Date Issued: 2018
PURL: http://purl.flvc.org/fau/fd/FA00013075
Subject Headings: Barracudinas., Paralepididae., Fishes--Mexico, Gulf of., Fishes--Ecology.
Format: Document (PDF)

Title: A habitat suitability model for wading birds in a large subtropical lake: linking hydrologic fluctuations and nesting.
Creator: Botta, Richard A., Gawlik, Dale E., Florida Atlantic University, Charles E. Schmidt College of Science, Department of Biological Sciences
Abstract/Description: Anthropogenic hydrologic alterations can affect the quality of lake littoral zone habitats for wading birds, such as the great egret (Ardea alba), snowy egret (Egretta thula), and white ibis (Eudocimus albus). One such lake in Florida, Lake Okeechobee, has experienced a marked decline in wading bird nesting since the 1970’s, concomitant with changes in lake level management. It’s hypothesized that a reduction in foraging habitat has led to the nesting decline; however, there is little...
Show moreAnthropogenic hydrologic alterations can affect the quality of lake littoral zone habitats for wading birds, such as the great egret (Ardea alba), snowy egret (Egretta thula), and white ibis (Eudocimus albus). One such lake in Florida, Lake Okeechobee, has experienced a marked decline in wading bird nesting since the 1970’s, concomitant with changes in lake level management. It’s hypothesized that a reduction in foraging habitat has led to the nesting decline; however, there is little quantitative evidence of this link. A habitat suitability model was developed for Lake Okeechobee wading birds that incorporate the spatial and temporal dynamics of environmental factors that affect wading bird foraging and tests whether foraging habitat is linked to numbers of nests.
Show less
Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA00004082
Subject Headings: Birds -- Florida -- Lake Okeechobee -- Geographical distribution, Estuarine ecology -- Florida -- Lake Okeechobee, Restoration ecology -- Florida -- Lake Okeechobee, Water birds -- Habitat
Format: Document (PDF)

Title: Genetic and Neuronal Integration of Sleep and Feeding.
Creator: Murphy, Keith Richard, Ja, William W., Florida Atlantic University, Charles E. Schmidt College of Science, Department of Biological Sciences
Abstract/Description: Accumulating evidence points to a fundamental connection between sleep and feeding behavior. However, the temporal, genetic, and neuronal architecture that defines these relationships is poorly understood. Drosophila are amenable to high-throughput studies and offer numerous genetic tools which have advanced our understanding of the mechanistic relationships between these behaviors. However, certain features of the sleep-feeding axis have remained elusive, largely due to the separate...
Show moreAccumulating evidence points to a fundamental connection between sleep and feeding behavior. However, the temporal, genetic, and neuronal architecture that defines these relationships is poorly understood. Drosophila are amenable to high-throughput studies and offer numerous genetic tools which have advanced our understanding of the mechanistic relationships between these behaviors. However, certain features of the sleep-feeding axis have remained elusive, largely due to the separate measurement of sleep and feeding. Here, I develop a system which simultaneously measures sleep and feeding in individual animals by employing high resolution machine vision tracking and micro-controller interface functionality. Using this system, I show that food consumption drives a transient rise in sleep, which depends on food quality, quantity, and timing of a meal. The leucokinin system mediates these effects, particularly in response to protein ingestion. We further use the system to examine sleep homeostasis and demonstrate sleep dependence on energy expenditure and fat-brain communication. Collectively, these findings provide novel insight into the fundamental connections between sleep and feeding behavior.
Show less
Date Issued: 2018
PURL: http://purl.flvc.org/fau/fd/FA00005972
Subject Headings: Sleep, Feeding, Drosophila
Format: Document (PDF)

Title: HUMAN CALCITONIN: AN INVESTIGATION OF AMYLOID FORMATION AND INHIBITION.
Creator: Lantz, Richard, Du, Deguo, Florida Atlantic University, Department of Chemistry and Biochemistry, Charles E. Schmidt College of Science
Abstract/Description: Human calcitonin (hCT) is a peptide hormone that is produced by the thyroid gland where it regulates blood calcium and stimulates bone formation. However, increased concentrations can cause hCT to aggregate into amyloid fibrils where they can cause cellular toxicity. In this dissertation, we investigated the role of the N-terminal intramolecular disulfide bond, the effects cholesterol derivatives, the inhibitory effects of a group of polyphenolic molecules, and membrane interactions on hCT...
Show moreHuman calcitonin (hCT) is a peptide hormone that is produced by the thyroid gland where it regulates blood calcium and stimulates bone formation. However, increased concentrations can cause hCT to aggregate into amyloid fibrils where they can cause cellular toxicity. In this dissertation, we investigated the role of the N-terminal intramolecular disulfide bond, the effects cholesterol derivatives, the inhibitory effects of a group of polyphenolic molecules, and membrane interactions on hCT amyloid formation. To better understand hCT amyloid formation, we investigated the role of the N-terminal intramolecular disulfide bond has on the aggregation kinetics of hCT. Our results demonstrated that the presence of the disulfide bond is key to the formation of the oligomeric nucleus that is needed for amyloid formation. We also investigated the role of cholesterol, cholesterol sulfate, and 3β-[N-(dimethylaminoethane)carbamoyl]-cholesterol (DC-cholesterol) in moderating hCT fibril formation. We showed that cholesterol does not significantly affect hCT fibrillization while high concentrations of cholesterol sulfate has a moderate inhibiting effect. However, DC-cholesterol strongly inhibits hCT fibril formation in a concentration-dependent manner suggesting the role of electrostatic and hydrogen bonding interactions have in moderating the interactivity between hCT and the surface of DC-cholesterol vesicles. We also probed the inhibitory effects of a group of polyphenolic molecules on hCT fibril formation. Our results showed that molecules containing vicinal hydroxyl groups on the phenyl ring effectively inhibits hCT fibril formation though a plausible covalent linkage between the oxidized polyphenol and hCT.
Show less
Date Issued: 2020
PURL: http://purl.flvc.org/fau/fd/FA00013514
Subject Headings: Calcitonin, Amyloid
Format: Document (PDF)

Title: Hurricane Irma Impact and Post-Storm Beach Morphology Evolution in Boca Raton, FL.
Creator: Hart, Richard M., III, Roberts Briggs, Tiffany, Florida Atlantic University, Charles E. Schmidt College of Science, Department of Geosciences
Abstract/Description: Beach morphology changes naturally with seasonal and event-driven variability in the wave climate, as well as due to anthropogenic activities such as erosion mitigation efforts. In 2017, category four Hurricane Irma caused beach erosion and dune overwash in Boca Raton, FL. Immediate post-storm perigean spring tides coupled with typical winter high-wind conditions imposed a regime of spatially and temporally extended meteorologic and morphologic variability. This study evaluates the...
Show moreBeach morphology changes naturally with seasonal and event-driven variability in the wave climate, as well as due to anthropogenic activities such as erosion mitigation efforts. In 2017, category four Hurricane Irma caused beach erosion and dune overwash in Boca Raton, FL. Immediate post-storm perigean spring tides coupled with typical winter high-wind conditions imposed a regime of spatially and temporally extended meteorologic and morphologic variability. This study evaluates the morphologic evolution and post-storm recovery in the first year following Hurricane Irma. Time-series topographic surveys and surface sediment samples were collected. Patterns of accretion and erosion were evaluated with regionally measured water and wind levels. Recovery morphology was generally through berm-building, but lacked shoreline stability. Storm impact regime, mitigation structures, and sediment transport patterns drove the recovery. Total volume lost above the 0 m contour due to the storm was not fully recovered within the year, with a large volume measured in the south.
Show less
Date Issued: 2019
PURL: http://purl.flvc.org/fau/fd/FA00013213
Subject Headings: Hurricane Irma, 2017, Boca Raton (Fla.), Beach erosion
Format: Document (PDF)

Title: A COMPARISON OF SODIUM ABUNDANCES CALCULATED FROM DAYLIGHT ABSORPTION AND TWILIGHT EMISSION IN THE D(2) LINE.
Creator: LASHER, RICHARD WILLIAM, Florida Atlantic University, Burnett, Clyde R., Charles E. Schmidt College of Science, Department of Physics
Abstract/Description: A method is presented, in which the Pepsios is used to measure abundances of atomic sodium present in the upper atmosphere as calculated from the twilight glow. These abundances are compared with daylight absorption abundances, also measured using the Pepsios. Ten measurements taken during March, 1971 show an average twilight abundance of (6.1 +- 1.8) x 10^9 atoms/cm^2. This compares with an average absorption abundance of (3.3 +- 1.1) x 10^9 atoms/cm^2. These limited data and their attendant...
Show moreA method is presented, in which the Pepsios is used to measure abundances of atomic sodium present in the upper atmosphere as calculated from the twilight glow. These abundances are compared with daylight absorption abundances, also measured using the Pepsios. Ten measurements taken during March, 1971 show an average twilight abundance of (6.1 +- 1.8) x 10^9 atoms/cm^2. This compares with an average absorption abundance of (3.3 +- 1.1) x 10^9 atoms/cm^2. These limited data and their attendant uncertainties reveal no significant discrepancy between twilight and daytime sodium abundances.
Show less
Date Issued: 1971
PURL: http://purl.flvc.org/fcla/dt/13449
Subject Headings: Sodium--Spectra, Absorption spectra
Format: Document (PDF)

$New methods for estimating fractal dimensions of coastlines$

Title: New methods for estimating fractal dimensions of coastlines.
Creator: Klotzbach, Jonathan David, Florida Atlantic University, Voss, Richard, Charles E. Schmidt College of Science, Department of Mathematical Sciences
Abstract/Description: A coastline is an example of a statistically self-similar fractal. A standard characterization walks a ruler of fixed size along the coast and estimates fractal dimension from the power-law relationship between length and ruler size. Multiple intersection can lead to ambiguity in choosing the next step. The standard method always chooses the first intersection along the curve. Variations were developed to choose intersections which highlight geographic properties. The land method measures...
Show moreA coastline is an example of a statistically self-similar fractal. A standard characterization walks a ruler of fixed size along the coast and estimates fractal dimension from the power-law relationship between length and ruler size. Multiple intersection can lead to ambiguity in choosing the next step. The standard method always chooses the first intersection along the curve. Variations were developed to choose intersections which highlight geographic properties. The land method measures accessibility to the coast from land at each size while the water method probes water access. Measurements on sections of the East and West Coasts of the United States typically showed the land length exceeding water. Jumps in water length as step size decreased were often caused by narrow rivers or bays which have few corresponding land features. Simple recursive constructions were inadequate to model this asymmetry.
Show less
Date Issued: 1998
PURL: http://purl.flvc.org/fcla/dt/15545
Subject Headings: Fractals, Boundaries, Coasts
Format: Document (PDF)

Title: Orientation of hatchling loggerhead sea turtles in response to the inclination of the magnetic field.
Creator: Light, Phillip Richard, Florida Atlantic University, Salmon, Michael, Charles E. Schmidt College of Science, Department of Biological Sciences
Abstract/Description: Recent studies have shown that hatchling loggerhead sea turtles possess the ability to orient to the earth's magnetic field. These experiments did not identify the specific component of the field used by turtles to determine direction. One of the field's most important characteristics, inclination, has been implicated as the specific property used by birds to orient. This study investigated the possibility that sea turtles use the inclination of the earth's field in a similar manner. Results...
Show moreRecent studies have shown that hatchling loggerhead sea turtles possess the ability to orient to the earth's magnetic field. These experiments did not identify the specific component of the field used by turtles to determine direction. One of the field's most important characteristics, inclination, has been implicated as the specific property used by birds to orient. This study investigated the possibility that sea turtles use the inclination of the earth's field in a similar manner. Results show that turtles determine direction with the use of an inclination compass similar to the one used by birds to orient. This study has important implications regarding the mechanisms used by animals to orient and navigate.
Show less
Date Issued: 1992
PURL: http://purl.flvc.org/fcla/dt/14787
Subject Headings: Loggerhead turtle, Animal orientation, Magnetic fields, Sea turtles--Migration
Format: Document (PDF)

Title: “COMING AT THE WONDER ITSELF”: MISCLASSIFICATION, MISUNDERSTANDING AND THE INTEGRATED VISION OF RUSSELL HOBAN’S 1967 NOVEL THE MOUSE AND HIS CHILD.
Creator: Richards, Charles, Ulin, Julieann, Florida Atlantic University, Department of English, Dorothy F. Schmidt College of Arts and Letters
Abstract/Description: In 1967, Russell Hoban’s first novel, The Mouse and His Child was published and reviewed as a children’s book, despite the fact that the author considered it not to be directed towards a child audience. Since that time, it has been generally analyzed and evaluated as a work of children’s literature (specifically) and not as literature in the general sense. Because the book deals with adult subjects and concepts it has not fared well with those who have measured its success solely on the basis...
Show moreIn 1967, Russell Hoban’s first novel, The Mouse and His Child was published and reviewed as a children’s book, despite the fact that the author considered it not to be directed towards a child audience. Since that time, it has been generally analyzed and evaluated as a work of children’s literature (specifically) and not as literature in the general sense. Because the book deals with adult subjects and concepts it has not fared well with those who have measured its success solely on the basis of its being classified as a children’s book. This thesis hopes to liberate the work from this classification by carefully analyzing the concepts which underpin its action, specifically its ontological speculations, its personification of the fall from grace and the felix culpa, the relationship of the protagonists to their complex antagonist Manny Rat, and, finally, in the symbol of “the last visible dog” which represents the infinite and what lies beyond the self (which, in fact, is actually the self). This thesis also examines how Hoban continued working with these themes and concepts in the novels he wrote after publishing The Mouse and His Child.
Show less
Date Issued: 2022
PURL: http://purl.flvc.org/fau/fd/FA00014008
Subject Headings: Hoban, Russell--Criticism and interpretation, Literature
Format: Document (PDF)

FAU Theses and Dissertations (28)	+ -
FAU College Collections (2)	+ -
Political & Rights Issues & Social Movements Collection (1)	+ -
Speeches (1)	+ -

Artificial intelligence (2)	+ -
Absorption spectra (1)	+ -
Affective Computing (1)	+ -
Amyloid (1)	+ -
Animal orientation (1)	+ -

Aquaculture--Research (1)	+ -
Aristotle (1)	+ -
Barracudinas. (1)	+ -
Beach erosion (1)	+ -
Birds -- Florida -- Lake Okeechobee -- Geographical distribution (1)	+ -
Biscayne Aquifer (Fla.) (1)	+ -
Boca Raton (Fla.) (1)	+ -
Boundaries (1)	+ -
Bryozoa (1)	+ -
Business Administration, General (1)	+ -
Calcitonin (1)	+ -
Cell interaction (1)	+ -
Coasts (1)	+ -
Coherence (Optics) (1)	+ -
Cryobiology (1)	+ -
Database management (1)	+ -
Discourse analysis, Narrative. (1)	+ -
Doppler effect (1)	+ -
Drosophila (1)	+ -
Emotion recognition (1)	+ -
Epiphytes (1)	+ -
Estuarine ecology -- Florida -- Lake Okeechobee (1)	+ -
Feeding (1)	+ -
Fishes--Ecology. (1)	+ -
Fishes--Mexico, Gulf of. (1)	+ -

Electronic Thesis or Dissertation (28)	+ -
article (1)	+ -
pamphlet (1)	+ -
speech (1)	+ -

Florida Atlantic University (28)	+ -
Charles E. Schmidt College of Science (12)	+ -
Department of Biological Sciences (3)	+ -
Department of Psychology (3)	+ -
Corseri, Richard Alan (2)	+ -

Search In

Pages

Pages

Sort Results By:

Narrow results by:

Collection

Topical Subject

Genre

Type of Resource

Language

Creator

Format

Owner