You are here
Novel steroidal saponins, Sch 725737 and Sch 725739, from a marine starfish, Novodinia antillensis
| Title: | Novel steroidal saponins, Sch 725737 and Sch 725739, from a marine starfish, Novodinia antillensis. |
 107 views 20 downloads |
|---|---|---|
| Name(s): |
Yang, Shu-Wei, creator Chan, Tze-Ming, creator Buevich, Alexei, creator Priestley, T., creator Crona, J., creator Reed, John K., creator Wright, Amy E., creator Patel, Mahesh, creator Gullo, Vincent, creator Chen, Guodong, creator Pramanik, B., creator Chu, Min, creator |
|
| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 2007 | |
| Publisher: | Elsevier | |
| Extent: | 6 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3343845 (digitool), FADT3343845 (IID), fau:6454 (fedora), 10.1016/j.bmcl.2007.08.025 (doi) | |
| Note(s): |
Bioassay-guided fractionation of an active fraction from an extract of a marine starfish, Novodiniaantillensis, led to the isolation and identification of two new saponins, Sch 725737 (1) and Sch 725739 (2). Compound 1 was identified as the NaV1.8 inhibitor with IC50 of ∼9 μM. The purification and the structure elucidation of these two saponins are described. The final published version of this manuscript is available at http://www.sciencedirect.com/science/journal/0960894X and may be cited as: Yang, S.-W., Chan, T.-M., Buevich, A., Priestley, T., Crona, J., Reed, J., Wright, A. E., Patel, M., Gullo, V., Chen, G., Pramanik, B., & Chu, M. (2007). Novel steroidal saponins, Sch 725737 and Sch 725739, from a marine starfish, Novodinia antillensis. Bioorganic & Medicinal Chemistry Letters, 17(20), 5543-5547. doi:10.1016/j.bmcl.2007.08.025 Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1677. |
|
| Subject(s): |
Steroid saponins Starfishes |
|
| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3343845 | |
| Links: | http://dx.doi.org/10.1016/j.bmcl.2007.08.025 | |
| Restrictions on Access: | ©2007 Elsevier | |
| Host Institution: | FAU |
