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Antifungal activity of meridine, a natural product from the marine sponge Corticium sp.
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|Title:||Antifungal activity of meridine, a natural product from the marine sponge Corticium sp.||
McCarthy, Peter J., creator
Pitts, Tara P., creator
Gunawardana, G. P., creator
Kelly-Borges, M., creator
Pomponi, Shirley A., creator
|Type of Resource:||text|
|Publisher:||The American Chemical Society and American Society of Pharmacognosy|
|Identifier:||3333005 (digitool), FADT3333005 (IID), fau:6205 (fedora), 10.1021/np50089a016 (doi)|
Meridine , a polycyclic alkaloid derived from the marine sponge Corticium sp., was found to inhibit the growth of Candida albicans and Cryptococcus neoformans. Activity was also observed against Trichophyton mentagrophytes and Epidermophyton floccosum. Studies of the mechanism of action of this agent have shown an inhibition of nucleic acid biosynthesis.
This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50089a016. This article may be cited as: McCarthy, P. J., Pitts, T. P., Gunawardana, G. P., Kelly-Borges, M., & Pomponi, S. A. (1992). Antifungal activity of meridine, a natural product from the marine sponge Corticium sp. Journal of Natural Products, 55(11), 1664-1668. doi:10.1021/np50089a016
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #929.
Marine natural products
|Persistent Link to This Record:||http://purl.flvc.org/FCLA/DT/3333005|
|Restrictions on Access:||©1992 The American Chemical Society and American Society of Pharmacognosy|