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Antifungal activity of meridine, a natural product from the marine sponge Corticium sp.

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Date Issued:
1992
Title: Antifungal activity of meridine, a natural product from the marine sponge Corticium sp.
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Name(s): McCarthy, Peter J., creator
Pitts, Tara P., creator
Gunawardana, G. P., creator
Kelly-Borges, M., creator
Pomponi, Shirley A., creator
Type of Resource: text
Genre: Article
Issuance: single unit
Date Issued: 1992
Publisher: The American Chemical Society and American Society of Pharmacognosy
Extent: 6 p.
Physical Description: pdf
Language(s): English
Identifier: 3333005 (digitool), FADT3333005 (IID), fau:6205 (fedora), 10.1021/np50089a016 (doi)
Note(s): Meridine [1], a polycyclic alkaloid derived from the marine sponge Corticium sp., was found to inhibit the growth of Candida albicans and Cryptococcus neoformans. Activity was also observed against Trichophyton mentagrophytes and Epidermophyton floccosum. Studies of the mechanism of action of this agent have shown an inhibition of nucleic acid biosynthesis.
This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50089a016. This article may be cited as: McCarthy, P. J., Pitts, T. P., Gunawardana, G. P., Kelly-Borges, M., & Pomponi, S. A. (1992). Antifungal activity of meridine, a natural product from the marine sponge Corticium sp. Journal of Natural Products, 55(11), 1664-1668. doi:10.1021/np50089a016
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #929.
Subject(s): Sponges
Alkaloids
Marine natural products
Antifungal agents
Persistent Link to This Record: http://purl.flvc.org/FCLA/DT/3333005
Links: http://dx.doi.org/10.1021/np50089a016
Restrictions on Access: ©1992 The American Chemical Society and American Society of Pharmacognosy
Owner Institution: FAU