You are here
Isolation and structure elucidation of onnamide a, a new bioactive metabolite of a marine sponge, Theonella sp.
| Title: | Isolation and structure elucidation of onnamide a, a new bioactive metabolite of a marine sponge, Theonella sp. |
 122 views 26 downloads |
|---|---|---|
| Name(s): |
Sakemi, S., creator Ichiba, T., creator Kohmoto, S., creator Saucy, G., creator Higa, T., creator Harbor Branch Oceanographic Institute |
|
| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 1988 | |
| Publisher: | American Chemical Society | |
| Extent: | 4 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3332945 (digitool), FADT3332945 (IID), fau:6175 (fedora), 10.1021/ja00222a068 (doi) | |
| Note(s): |
Marine sponges of the genus Theonella have been shown to elaborate diverse chemical structures with interesting biological activities.1 We have recently described the isolation of misakinolide A, a dimeric 40-membered lactone having antitumor activity from a species of Theonella. 1a In our screening for bioactivity in marine organisms occurring in Okinawan waters, another species of Theonella gave an extract showing antiviral activity. Bioassay-guided separation led to the isolation of an active constituent, onnamide A (1)2 which belonged to a class of metabolites new to Theonella species. We herein report the isolation and structure elucidation of onnamide A (1). This document is the accepted manuscript version of a published work that appeared in final form in Journal of the American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/ja00222a068. This article may be cited as: Sakemi, S., Ichiba, T., Kohmoto, S., Saucy, G., & Higa, T. (1988). Isolation and structure elucidation of onnamide a, a new bioactive metabolite of a marine sponge, Theonella sp. Journal of the American Chemical Society, 110(14), 4851-4853. doi:10.1021/ja00222a068 Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #647. |
|
| Subject(s): |
Sponges Bioactive compounds Marine metabolites Marine Toxins |
|
| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3332945 | |
| Links: | http://dx.doi.org/10.1021/ja00222a068 | |
| Restrictions on Access: | ©1988 American Chemical Society | |
| Host Institution: | FAU |
