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Inhalation toxicity of Brevetoxin 3 in rats exposed for 5 days
| Title: | Inhalation toxicity of Brevetoxin 3 in rats exposed for 5 days. |
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| Name(s): |
Benson, Janet M., creator Hahn, Fletcher F., creator March, Thomas H., creator McDonald, Jacob D., creator Sopori, Mohan L., creator Seagrave, JeanClare, creator Gomez, Andrea P., creator Bourdelais, Andrea J., creator Naar, Jerome, creator Zaias, Julia, creator Bossart, Gregory D., creator Baden, Daniel G., creator Harbor Branch Oceanographic Institute |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 2004 | |
| Publisher: | Taylor & Francis Inc. | |
| Extent: | 15 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 2796034 (digitool), FADT2796034 (IID), fau:5545 (fedora), 10.1080/15287390490483809 (doi) | |
| Note(s): |
Brevetoxins are potent neurotoxins produced by the marine dinoflagellate Karenia brevis. Exposure to brevetoxins may occur during a K. brevis red tide when the compounds become aerosolized by wind and surf. This study assesses possible adverse health effects associated with short-term inhalation exposure to brevetoxin 3. Male F344/Crl/Br rats were exposed to 500μ g brevetoxin 3/m3 by nose-only inhalation for 0.5 or 2h/d for 5 consecutive days. Control rats were sham exposed for 2h to vehicle. Calculated deposited brevetoxin doses were 8.3 and 33μ g/kg/d for the low- and highdose groups, respectively. This manuscript is a version of an article with the final publication found online at http://www.informaworld.com and may be cited as: Benson, Janet M., Fletcher F. Hahn, Thomas H. March, Jacob D. McDonald, Mohan L. Sopori, JeanClare Seagrave, Andrea P. Gomez, Andrea J. Bourdelais, Jerome Naar, Julia Zaias, Gregory D. Bossart, Daniel G. Baden (2004) Inhalation toxicity of Brevetoxin 3 in rats exposed for 5 days, Journal of Toxicology and Environmental Health, Part A 67(18):1443-1456 doi:10.1080/15287390490483809 Journal of Toxicology and Environmental Health, Part A is available online at: http://www.informaworld.com/openurl?genre=article&issn=1087-2620&volume=67&issue=18&spage=1443 Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1581. |
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| Subject(s): |
Dinoflagellates --Cytology Macrophages Red tide Neurotoxic agents --Analysis Neurotoxic agents --Physiological effect |
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| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/2796034 | |
| Links: | http://dx.doi.org/10.1080/15287390490483809 | |
| Restrictions on Access: | ©2004 Taylor & Francis Inc. | |
| Host Institution: | FAU | |
| Other Version: | This manuscript is a version of an article with the final publication found online at http://www.informaworld.com and may be cited as: Benson, Janet M., Fletcher F. Hahn, Thomas H. March, Jacob D. McDonald, Mohan L. Sopori, JeanClare Seagrave, Andrea P. Gomez, Andrea J. Bourdelais, Jerome Naar, Julia Zaias, Gregory D. Bossart, Daniel G. Baden (2004) Inhalation toxicity of Brevetoxin 3 in rats exposed for 5 days, Journal of Toxicology and Environmental Health, Part A 67(18):1443-1456 doi:10.1080/15287390490483809 Journal of Toxicology and Environmental Health, Part A is available online at: http://www.informaworld.com/openurl?genre=article&issn=1087-2620&volume=67&issue=18&spage=1443. |
