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Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers

Title: Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers.
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Name(s): Roner, Michael R., author
Carraher, Charles E., author
Shahi, Kimberly, author
Barot, Girish, author
Type of Resource: text
Genre: Article
Date Issued: 2011-05-27
Summary: Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth. As most DNA and some RNA viruses require, and even induce, infected cells to initiate DNA replication and subsequent cell division, compounds with antitumor activity will very likely also possess antiviral activity. This article examines the use of metal-containing polymers as a novel class of antivirals.
Identifier: 10.3390/ma4060991 (doi), http://www.mdpi.com/1996-1944/4/6/991/ (uri), FAUIR000008 (IID)
Persistent Link to This Record: http://purl.flvc.org/fau/fd/FAUIR000008
Use and Reproduction: publisher
Owner Institution: FAU
Is Part Of: Materials.
1996-1944