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A new bicyclic guanidine alkaloid, Sch 575948, from amarine sponge, Ptilocaulis spiculifer

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Date Issued:
2003
Title: A new bicyclic guanidine alkaloid, Sch 575948, from amarine sponge, Ptilocaulis spiculifer.
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Name(s): Yang, Shu-Wei
Chan, Tze-Ming
Pomponi, Shirley A.
Chen, Guodong
Wright, Amy E.
Patel, Mahesh
Gullo, Vincent
Pramanik, B.
Chu, Min
Type of Resource: text
Genre: Article
Date Issued: 2003
Publisher: Japan Antibiotics Research Association
Place of Publication: Tokyo, Japan
Physical Form: pdf
Extent: 4 p.
Language(s): English
Identifier: FA00007361 (IID), 10.7164/antibiotics.56.970 (doi)
Note(s): In the course of our continuing search for novel antimicrobial agents, we have isolated a new antibacterial compound Sch 575948 (1) along with a known alkaloid ptilomycalin A (2) from a marine sponge Ptilocaulis spiculifer (or Crambe crambe). Sch 575948 was identified as a bicyclic bis-guanidine type of alkaloid, a homolog of crambcscin A (or crambine A (3)), identified as a major component of the homolog complex.
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution 1556
This manuscript is an author version with the final publication available and may be cited as: Yang, S. W., Chan, T. M., Pomponi, S. A., Chen, G., Wright, A. E., Patel, M., . . . Chu, M. (2003). A new bicyclic guanidine alkaloid, Sch 575948, from a marine sponge, Ptilocaulis spiculifer. The Journal of Antibiotics, 56(11), 970-972.
Subject(s): Sponges
Alkaloids
Guanidines
Antibacterial agents
Molecular structure
Persistent Link to This Record: http://purl.flvc.org/fau/fd/FA00007361
Links: http://doi.org/10.7164/antibiotics.56.970
Owner Institution: FAU