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The chemistry and biological activity of five marine sponges of the genus Aplysina

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Date Issued:
1991
Title: The chemistry and biological activity of five marine sponges of the genus Aplysina.
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Name(s): Gunasekera, Sarath P.
Cross, S. S.
Longley, Ross E.
Pomponi, Shirley A.
Type of Resource: text
Genre: Article
Date Issued: 1991
Publisher: University of Illinois
Place of Publication: Chicago, IL
Physical Form: pdf
Extent: 7 p.
Language(s): English
Identifier: FA00007303 (IID)
Note(s): Four species of the genus Aplysina, namely, A. fistularis fulva, A. archeri, A. lacunosa, and A. caulijormis have been studied, and fistularin-3 (1) has been identified as a compound active against feline leukemia virus. Antiviral activity found in the crude extracts was found to correlate to the concentration of fistularin-3 isolated by an hplc method. Similarly, the immunosuppressive agent in A. fistularis fulva has been isolated and identified as aerothionin (2). These two compounds have been reported previously from the genus Aplysina. This is the first report confirming the antiviral activity detected in different species of Aplysina with the presence of fistularin-3.
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution 899
This manuscript is an author version with the final publication available and may be cited as: Gunasekera, S. P., Cross, S. S., Longley, R. E., & Pomponi, S. A. (1991). The chemistry and biological activity of five marine sponges of the genus Aplysina. In J. M. Pezzuto, A. D. Kinghorn, H. H. S. Fong, & G. A. Cordell (Eds.), Progress on terrestrial and marine natural products of medicinal and biological interest: proceedings of a symposium held on the occasion of the 60th birthday of Norman R. Farnsworth (pp. 53-58). Chicago, IL: University of Illinois.
Subject(s): Sponges
Antiviral agents
Immunosuppressive agents
Bioactive compounds
Marine natural products
Persistent Link to This Record: http://purl.flvc.org/fau/fd/FA00007303
Owner Institution: FAU